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公开(公告)号:US09801888B2
公开(公告)日:2017-10-31
申请号:US15002806
申请日:2016-01-21
发明人: Mann-Yan Kuo , Ying-Shuan Lee , Paonien Chen , Li Jung Chen , Yann Yu Lu , Yi-Ting Huang , Hung-Yi Hsu , Ping-Kuei Tsai
IPC分类号: A61K31/5377 , A61K31/541 , C07D413/04 , C07D413/14 , C07D417/14 , C07D403/12 , C07D401/14 , C07D239/47 , C07D409/12 , C07D413/12 , A61K45/06 , C07D401/04
CPC分类号: A61K31/5377 , A61K31/541 , A61K45/06 , C07D239/47 , C07D401/04 , C07D401/14 , C07D403/12 , C07D409/12 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/14 , A61K2300/00
摘要: The present invention relates to pyrimidine compounds of formula (I): which are useful in treating mTOR kinase- or PI3K kinase-related diseases.
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公开(公告)号:US20140178360A1
公开(公告)日:2014-06-26
申请号:US14192301
申请日:2014-02-27
发明人: Mann-Yan KUO , Ying-Shuan Lee , Paonien Chen , Li Jung Chen , Yann Yu Lu , Yi-Ting Huang , Hung-Yi Hsu , Ping-Kuei Tsai
IPC分类号: C07D413/04 , A61K31/541 , A61K45/06 , A61K31/5377 , C07D413/14 , C07D417/14
CPC分类号: A61K31/5377 , A61K31/541 , A61K45/06 , C07D239/47 , C07D401/04 , C07D401/14 , C07D403/12 , C07D409/12 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/14 , A61K2300/00
摘要: The present invention relates to pyrimidine compounds of formula (I): which are useful in treating mTOR kinase- or PI3K kinase-related diseases.
摘要翻译: 本发明涉及式(I)的嘧啶化合物:其可用于治疗mTOR激酶或PI3K激酶相关疾病。
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公开(公告)号:US09315491B2
公开(公告)日:2016-04-19
申请号:US14192301
申请日:2014-02-27
发明人: Mann-Yan Kuo , Ying-Shuan Lee , Paonien Chen , Li Jung Chen , Yann Yu Lu , Yi-Ting Huang , Hung-Yi Hsu , Ping-Kuei Tsai
IPC分类号: A61K31/5377 , C07D239/47 , A61K31/506 , C07D401/04 , C07D401/14 , C07D413/04 , A61K31/541 , A61K45/06 , C07D413/14 , C07D417/14 , C07D403/12 , C07D409/12 , C07D413/12
CPC分类号: A61K31/5377 , A61K31/541 , A61K45/06 , C07D239/47 , C07D401/04 , C07D401/14 , C07D403/12 , C07D409/12 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/14 , A61K2300/00
摘要: The present invention relates to pyrimidine compounds of formula (I): which are useful in treating mTOR kinase- or PI3K kinase-related diseases.
摘要翻译: 本发明涉及式(I)的嘧啶化合物:其可用于治疗mTOR激酶或PI3K激酶相关疾病。
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