公开(公告)号：US20220170018A1

公开(公告)日：2022-06-02

申请号：US17593594

申请日：2021-03-13

申请人： DEVGEN NV

发明人： Lien DE SCHRIJVER ,  Kaat CAPPELLE ,  Lies DEGRAVE ,  Myriam BEGHYN ,  Yann NAUDET

IPC分类号： C12N15/113 ,  A01N63/60 ,  C12N15/82 ,  A01N63/50

摘要： Disclosed are double stranded RNA molecules that are toxic to flea beetles, particularly the flea beetle species Psylliodes chrysocephala, Phyllotreta nemorum, Phyllotreta striolata, Phyllotreta armoraciae, Phyllotreta atra and Phyllotreta cruciferae. In particular, interfering RNA molecules capable of interfering with pest target genes and that are toxic to the target pest are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants or as the active ingredient in a composition, to confer protection from insect damage are disclosed.

公开(公告)号：US20210123069A1

公开(公告)日：2021-04-29

申请号：US17051048

申请日：2019-04-17

申请人： DEVGEN NV

发明人： Lien DE SCHRIJVER ,  Kaat CAPPELLE ,  Lies DEGRAVE ,  Yann NAUDET ,  Steffy DENORME

IPC分类号： C12N15/82 ,  A01N63/60

摘要： Disclosed are double stranded RNA molecules that are toxic to flea beetles, particularly the flea beetle species Psylliodes chrysocephala, Phyllotreta nemorum, Phyllotreta striolata, Phyllotreta armoraciae, and Phyllotreta cruciferae. In particular, interfering RNA molecules capable of interfering with pest target genes and that are toxic to the target pest are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants or as the active ingredient in a composition, to confer protection from insect damage are disclosed.