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公开(公告)号：US20180028119A1
公开(公告)日：2018-02-01
申请号：US15716906
申请日：2017-09-27
发明人： Brian Jamieson , Jennette Mateo
CPC分类号： A61B5/04001 , A61B5/0084 , A61B5/6848 , A61B5/6868 , A61B2018/2266 , A61B2018/2272 , A61B2562/046 , A61N5/0622 , A61N2005/0612 , A61N2005/065
摘要： In certain embodiments, a neural probe comprises a substrate comprising elongated shanks for penetrating neural tissue, each comprising a proximal end and a distal end; at least one optical source integral to the neural probe for illuminating the neural tissue; and microelectrodes located proximate the distal end of the elongated shanks for monitoring neuronal activity. In certain embodiments, a method of monitoring neuronal activity comprises implanting the neural probe into a test subject such that the elongated shanks protrude into neural tissue of the test subject; illuminating the neural tissue with the at least one optical source; and measuring neuronal activity in response to illuminating the neural tissue. In certain embodiments, a device comprises a semiconductor chip; at least one optical source integral to the semiconductor chip; and sensor elements integral to the semiconductor chip for collecting data responsive to light emitted from the at least one optical source.
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公开(公告)号：US10285605B2
公开(公告)日：2019-05-14
申请号：US15716906
申请日：2017-09-27
发明人： Brian Jamieson , Jennette Mateo
IPC分类号： A61B5/04 , A61B5/0478 , A61B5/00 , A61N5/06 , A61B18/22
摘要： In certain embodiments, a neural probe comprises a substrate comprising elongated shanks for penetrating neural tissue, each comprising a proximal end and a distal end; at least one optical source integral to the neural probe for illuminating the neural tissue; and microelectrodes located proximate the distal end of the elongated shanks for monitoring neuronal activity. In certain embodiments, a method of monitoring neuronal activity comprises implanting the neural probe into a test subject such that the elongated shanks protrude into neural tissue of the test subject; illuminating the neural tissue with the at least one optical source; and measuring neuronal activity in response to illuminating the neural tissue. In certain embodiments, a device comprises a semiconductor chip; at least one optical source integral to the semiconductor chip; and sensor elements integral to the semiconductor chip for collecting data responsive to light emitted from the at least one optical source.
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