专利检索 ap:("DISTRETTO TECNOLOGICO SICILIA MICRO E NANO SISTEMI S.C.A.R.L.") AND inv:"Mario Zappia" 第 1 页

1.

发明授权
Conformational mimotopes for detecting specific antibodies 有权

公开(公告)号：US11982679B2

公开(公告)日：2024-05-14

申请号：US16464197

申请日：2017-11-27

申请人： DISTRETTO TECNOLOGICO SICILIA MICRO E NANO SISTEMI S.C.A.R.L.

发明人： Salvatore Guglielmino , Laura Maria De Plano , Santina Carnazza , Domenico Franco , Alessandra Nicoletti , Mario Zappia , Sabrina Conoci , Salvatore Petralia

IPC分类号： G01N33/68 , C07K7/08 , C12N15/10 , G16B15/00 , G16B45/00

CPC分类号： G01N33/6896 , C07K7/08 , C12N15/1037 , G16B15/00 , G16B45/00 , G01N2333/4709 , G01N2800/2821

摘要： The present invention relates to a method for obtaining protein mimotopes occurring in at least two distinct 3D conformations. In a further embodiment, a method for detecting antibodies with diagnostic relevance using said mimotopes is claimed. In a preferred embodiment, said methods are applied to Alzheimer's disease.