公开(公告)号：US10815178B2

公开(公告)日：2020-10-27

申请号：US16720580

申请日：2019-12-19

Applicant: DSM IP Assets B.V.

Inventor： Ulla Letinois ,  Stephan Ackermann ,  Jonathan Alan Medlock ,  Hajo Lehmann

IPC: C07C41/30 ,  C07C37/07 ,  C07C37/50 ,  C07C43/178 ,  C07D311/72 ,  C07C46/08 ,  C07C41/36 ,  B01J31/18 ,  B01J31/22 ,  B01J31/24

Abstract: The present invention relates to a method of preparing ortho substituted phenols from 2,5-dimethylfuran and propargyl ethers in the presence of a gold(I) complex. It is particularly advantageous to use 2,5-dimethylfuran as this offers an ecological beneficial synthesis of said ortho substituted phenols.

公开(公告)号：US09809565B2

公开(公告)日：2017-11-07

申请号：US14902871

申请日：2014-07-03

Applicant: DSM IP ASSETS B.V.

Inventor： Ulla Letinois ,  Thomas Netscher ,  Stephan Ackermann

IPC: C07D311/00 ,  C07D311/22

CPC classification number: C07D311/22

Abstract: The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of formula of a specific type and of at least one urea or thiourea.