公开(公告)号：US20210047452A1

公开(公告)日：2021-02-18

申请号：US17043041

申请日：2019-03-29

Applicant: DUBLIN CITY UNIVERSITY

Inventor： Colm DELANEY ,  Larisa Elena FLOREA ,  Danielle BRUEN ,  Dermot DIAMOND

IPC: C08F230/06 ,  C08J5/18 ,  C07F5/02 ,  G01N33/66 ,  C07C309/12 ,  A61B5/145

Abstract: A polymerizable boronic acid salt has the general structure (I): A+.X− (I) in which: A represents a quaternised ammonium boronic acid cation; and X represents an anion, wherein either A or X contains a free-radical polymerizable group. Diol-sensing hydrogels comprising a crosslinked polymeric matrix formed from the polymerizable boronic acid salt monomer are also described.

公开(公告)号：US20160158754A1

公开(公告)日：2016-06-09

申请号：US14907162

申请日：2014-07-23

Applicant: DUBLIN CITY UNIVERSITY

Inventor： Bartosz ZIOLKOWSKI ,  Larisa Elena FLOREA ,  Dermot DIAMOND

IPC: B01L3/00 ,  C08J9/26 ,  C08F220/54

CPC classification number: B01L3/502738 ,  B01L2200/06 ,  B01L2300/12 ,  B01L2400/0672 ,  C08F2/48 ,  C08F220/54 ,  C08J9/26 ,  C08J2201/046 ,  C08J2205/022 ,  C08J2333/24 ,  C08F220/36 ,  C08F222/38

Abstract: The present teaching relates to photo-responsive hydrogels comprising a copolymer comprising N-isopropylacrylamide (NIPAM), a polymerisable derivative of benzospiropyran, a cross-linking agent and an acid, the acid having a pKa of less than 6, wherein the hydrogel is operably responsive to exposure to water so as to undergo spontaneous protonation and swelling. The photo-responsive hydrogels described can be used in the field of microfluidic platforms.

Abstract translation: 本教导涉及光响应性水凝胶，其包含包含N-异丙基丙烯酰胺（NIPAM），苯并吡喃的可聚合衍生物，交联剂和酸的共聚物，所述酸的pKa小于6，其中所述水凝胶是可操作地 响应于暴露于水以便经历自发的质子化和溶胀。 所描述的光敏水凝胶可用于微流体平台领域。