公开(公告)号：US08506500B2

公开(公告)日：2013-08-13

申请号：US13043346

申请日：2011-03-08

申请人： Dan Li ,  Shelley M. Cazares ,  Jaeho Kim ,  Kent Lee

发明人： Dan Li ,  Shelley M. Cazares ,  Jaeho Kim ,  Kent Lee

IPC分类号： A61B5/0472 ,  A61B5/02

CPC分类号： A61B5/0464 ,  A61B5/7264 ,  A61N1/3621 ,  A61N1/36521 ,  A61N1/36542 ,  A61N1/36564 ,  A61N1/36571 ,  A61N1/36578 ,  A61N1/36585 ,  A61N1/3925 ,  A61N1/3962

摘要： A tachyarrhythmia detection and classification system classifies tachyarrhythmias based on an analysis of morphological features of a cardiac signal enhanced by using one or more physiological parameters indicative of hemodynamic stability and/or activity level. The tachyarrhythmia detection and classification system computes a measure of similarity between an arrhythmic waveform of the cardiac signal, a template waveform for that cardiac signal, such as a correlation coefficient representative of the correlation between morphological features of the arrhythmic waveform and morphological features of the template waveform. A detected tachyarrhythmia episode is classified by comparing the measure of similarity to a threshold that is dynamically adjusted using the one or more physiological parameters.

摘要翻译： 快速心律失常检测和分类系统基于通过使用指示血液动力学稳定性和/或活动水平的一个或多个生理参数来增强的心脏信号的形态学特征的分析来分类快速性心律失常。 快速心律失常检测和分类系统计算心脏信号的心律失常波形与该心脏信号的模板波形之间的相似性的度量，例如表示心律失常波形的形态特征与模板的形态特征之间的相关性的相关系数 波形 通过将相似性测量值与使用一个或多个生理参数动态调整的阈值进行比较来分类检测到的快速性心律失常发作。

公开(公告)号：US07912545B2

公开(公告)日：2011-03-22

申请号：US12536828

申请日：2009-08-06

申请人： Dan Li ,  Shelley M. Cazares ,  Jaeho Kim ,  Kent Lee

发明人： Dan Li ,  Shelley M. Cazares ,  Jaeho Kim ,  Kent Lee

IPC分类号： A61N1/362 ,  A61B5/04

CPC分类号： A61B5/0464 ,  A61B5/7264 ,  A61N1/3621 ,  A61N1/36521 ,  A61N1/36542 ,  A61N1/36564 ,  A61N1/36571 ,  A61N1/36578 ,  A61N1/36585 ,  A61N1/3925 ,  A61N1/3962

摘要： A tachyarrhythmia detection and classification system classifies tachyarrhythmias based on an analysis of morphological features of a cardiac signal enhanced by using one or more physiological parameters indicative of hemodynamic stability and/or activity level. The tachyarrhythmia detection and classification system computes a measure of similarity between an arrhythmic waveform of the cardiac signal, a template waveform for that cardiac signal, such as a correlation coefficient representative of the correlation between morphological features of the arrhythmic waveform and morphological features of the template waveform. A detected tachyarrhythmia episode is classified by comparing the measure of similarity to a threshold that is dynamically adjusted using the one or more physiological parameters.

摘要翻译： 快速心律失常检测和分类系统基于通过使用指示血液动力学稳定性和/或活动水平的一个或多个生理参数来增强的心脏信号的形态学特征的分析来分类快速性心律失常。 快速心律失常检测和分类系统计算心脏信号的心律失常波形与该心脏信号的模板波形之间的相似性的度量，例如表示心律失常波形的形态特征与模板的形态特征之间的相关性的相关系数 波形 通过将相似性测量值与使用一个或多个生理参数动态调整的阈值进行比较来分类检测到的快速性心律失常发作。

公开(公告)号：US20110160551A1

公开(公告)日：2011-06-30

申请号：US13043346

申请日：2011-03-08

申请人： Dan Li ,  Shelley Cazares ,  Jaeho Kim ,  Kent Lee

发明人： Dan Li ,  Shelley Cazares ,  Jaeho Kim ,  Kent Lee

IPC分类号： A61B5/02

CPC分类号： A61B5/0464 ,  A61B5/7264 ,  A61N1/3621 ,  A61N1/36521 ,  A61N1/36542 ,  A61N1/36564 ,  A61N1/36571 ,  A61N1/36578 ,  A61N1/36585 ,  A61N1/3925 ,  A61N1/3962

摘要： A tachyarrhythmia detection and classification system classifies tachyarrhythmias based on an analysis of morphological features of a cardiac signal enhanced by using one or more physiological parameters indicative of hemodynamic stability and/or activity level. The tachyarrhythmia detection and classification system computes a measure of similarity between an arrhythmic waveform of the cardiac signal, a template waveform for that cardiac signal, such as a correlation coefficient representative of the correlation between morphological features of the arrhythmic waveform and morphological features of the template waveform. A detected tachyarrhythmia episode is classified by comparing the measure of similarity to a threshold that is dynamically adjusted using the one or more physiological parameters.

摘要翻译： 快速心律失常检测和分类系统基于通过使用指示血液动力学稳定性和/或活动水平的一个或多个生理参数来增强的心脏信号的形态学特征的分析来分类快速性心律失常。 快速心律失常检测和分类系统计算心脏信号的心律失常波形与该心脏信号的模板波形之间的相似性的度量，例如表示心律失常波形的形态特征与模板的形态特征之间的相关性的相关系数 波形 通过将相似性测量值与使用一个或多个生理参数动态调整的阈值进行比较来分类检测到的快速性心律失常发作。

公开(公告)号：US20090292332A1

公开(公告)日：2009-11-26

申请号：US12536828

申请日：2009-08-06

申请人： Dan Li ,  Shelley Cazares ,  Jaeho Kim ,  Kent Lee

发明人： Dan Li ,  Shelley Cazares ,  Jaeho Kim ,  Kent Lee

IPC分类号： A61N1/39 ,  A61B5/02 ,  A61B5/0205

CPC分类号： A61B5/0464 ,  A61B5/7264 ,  A61N1/3621 ,  A61N1/36521 ,  A61N1/36542 ,  A61N1/36564 ,  A61N1/36571 ,  A61N1/36578 ,  A61N1/36585 ,  A61N1/3925 ,  A61N1/3962

摘要： A tachyarrhythmia detection and classification system classifies tachyarrhythmias based on an analysis of morphological features of a cardiac signal enhanced by using one or more physiological parameters indicative of hemodynamic stability and/or activity level. The tachyarrhythmia detection and classification system computes a measure of similarity between an arrhythmic waveform of the cardiac signal a template waveform for that cardiac signal, such as a correlation coefficient representative of the correlation between morphological features of the arrhythmic waveform and morphological features of the template waveform. A detected tachyarrhythmia episode is classified by comparing the measure of similarity to a threshold that is dynamically adjusted using the one or more physiological parameters.

摘要翻译： 快速心律失常检测和分类系统基于通过使用指示血液动力学稳定性和/或活动水平的一个或多个生理参数来增强的心脏信号的形态学特征的分析来分类快速性心律失常。 快速心律失常检测和分类系统计算心脏信号的心律失常波形与该心脏信号的模板波形之间的相似性的度量，例如表示心律失常波形的形态特征与模板波形的形态特征之间的相关性的相关系数 。 通过将相似性测量值与使用一个或多个生理参数动态调整的阈值进行比较来分类检测到的快速性心律失常发作。

公开(公告)号：US20070149890A1

公开(公告)日：2007-06-28

申请号：US11316332

申请日：2005-12-22

申请人： Dan Li ,  Shelley Cazares ,  Jaeho Kim ,  Kent Lee

发明人： Dan Li ,  Shelley Cazares ,  Jaeho Kim ,  Kent Lee

IPC分类号： A61B5/04

CPC分类号： A61B5/0464 ,  A61B5/7264 ,  A61N1/3621 ,  A61N1/36521 ,  A61N1/36542 ,  A61N1/36564 ,  A61N1/36571 ,  A61N1/36578 ,  A61N1/36585 ,  A61N1/3925 ,  A61N1/3962

摘要： A tachyarrhythmia detection and classification system classifies tachyarrhythmias based on an analysis of morphological features of a cardiac signal enhanced by using one or more physiological parameters indicative of hemodynamic stability and/or activity level. The tachyarrhythmia detection and classification system computes a measure of similarity between an arrhythmic waveform of the cardiac signal a template waveform for that cardiac signal, such as a correlation coefficient representative of the correlation between morphological features of the arrhythmic waveform and morphological features of the template waveform. A detected tachyarrhythmia episode is classified by comparing the measure of similarity to a threshold that is dynamically adjusted using the one or more physiological parameters.

摘要翻译： 快速心律失常检测和分类系统基于通过使用指示血液动力学稳定性和/或活动水平的一个或多个生理参数来增强的心脏信号的形态学特征的分析来分类快速性心律失常。 快速心律失常检测和分类系统计算心脏信号的心律失常波形与该心脏信号的模板波形之间的相似性的度量，例如表示心律失常波形的形态特征与模板波形的形态特征之间的相关性的相关系数 。 通过将相似性测量值与使用一个或多个生理参数动态调整的阈值进行比较来分类检测到的快速性心律失常发作。

公开(公告)号：US07582061B2

公开(公告)日：2009-09-01

申请号：US11316332

申请日：2005-12-22

申请人： Dan Li ,  Shelley Cazares ,  Jaeho Kim ,  Kent Lee

发明人： Dan Li ,  Shelley Cazares ,  Jaeho Kim ,  Kent Lee

IPC分类号： A61B5/02

CPC分类号： A61B5/0464 ,  A61B5/7264 ,  A61N1/3621 ,  A61N1/36521 ,  A61N1/36542 ,  A61N1/36564 ,  A61N1/36571 ,  A61N1/36578 ,  A61N1/36585 ,  A61N1/3925 ,  A61N1/3962

摘要： A tachyarrhythmia detection and classification system classifies tachyarrhythmias based on an analysis of morphological features of a cardiac signal enhanced by using one or more physiological parameters indicative of hemodynamic stability and/or activity level. The tachyarrhythmia detection and classification system computes a measure of similarity between an arrhythmic waveform of the cardiac signal a template waveform for that cardiac signal, such as a correlation coefficient representative of the correlation between morphological features of the arrhythmic waveform and morphological features of the template waveform. A detected tachyarrhythmia episode is classified by comparing the measure of similarity to a threshold that is dynamically adjusted using the one or more physiological parameters.

摘要翻译： 快速心律失常检测和分类系统基于通过使用指示血液动力学稳定性和/或活动水平的一个或多个生理参数来增强的心脏信号的形态学特征的分析来分类快速性心律失常。 快速心律失常检测和分类系统计算心脏信号的心律失常波形与该心脏信号的模板波形之间的相似性的度量，例如表示心律失常波形的形态特征与模板波形的形态特征之间的相关性的相关系数 。 通过将相似性测量值与使用一个或多个生理参数动态调整的阈值进行比较来分类检测到的快速性心律失常发作。

公开(公告)号：US08688204B2

公开(公告)日：2014-04-01

申请号：US13104439

申请日：2011-05-10

申请人： William H. Sauer ,  Shelley M. Cazares ,  Dan Li

发明人： William H. Sauer ,  Shelley M. Cazares ,  Dan Li

IPC分类号： A61B5/04

CPC分类号： A61N1/3622 ,  A61N1/3627

摘要： Methods and systems for identifying tachyarrhythmia episode types and delivering therapy to mitigate the identified tachyarrhythmia episode types are described. Electrogram signals of cardiac activity are sensed and stored by an implantable cardiac device. Tachyarrhythmia episodes are detected and tachyarrhythmia episode types are identified based on characteristics of the electrogram signals. In preparation for performing ablation, a tachyarrhythmia episode is induced. The features of the induced tachyarrhythmia episode are compared to characteristics of the identified episode types. A similarity between the induced tachyarrhythmia episode and at least one of the episode types identified from the stored electrogram signals is indicated to facilitate performing the ablation.

摘要翻译： 描述了用于鉴定快速性心律失常发作类型并递送治疗以减轻所鉴定的快速性心律失常发作类型的方法和系统。 心脏活动的电图信号由可植入的心脏装置感测和储存。 检测到快速性心律失常发作，并根据电描记图信号的特征识别快速性心律失常发作类型。 为准备进行消融，诱发快速性心律失常发作。 将诱发的快速性心律失常发作的特征与鉴定的发作类型的特征进行比较。 指示诱导的快速性心律失常发作与从存储的电描记图信号识别的至少一种发作类型之间的相似性，以便于进行消融。

公开(公告)号：US08521289B2

公开(公告)日：2013-08-27

申请号：US13603934

申请日：2012-09-05

申请人： Shelley M. Cazares ,  Dan Li ,  Jonathan Kwok

发明人： Shelley M. Cazares ,  Dan Li ,  Jonathan Kwok

IPC分类号： A61N1/362

CPC分类号： A61B5/0031 ,  G06F19/00

摘要： This document discusses, among other things, methods and systems for facilitating automated device programming at changeout. A method comprises receiving, from a first device, physiological data at a temporary storage device; and processing the received physiological data, wherein the processing includes determining if a first signal processing function was used by the first device and substantially offsetting the first signal processing function if the first signal processing function was used by the first device; and processing the resultant physiological data to be compatible with a second device. The method further comprising providing the processed resultant physiological data to the second device.

摘要翻译： 本文档除了其他内容之外还讨论了用于在切换时实现自动化设备编程的方法和系统。 一种方法包括从临时存储装置接收来自第一装置的生理数据; 以及处理所接收的生理数据，其中所述处理包括确定所述第一设备是否使用第一信号处理功能，并且如果所述第一设备使用所述第一信号处理功能，则基本上抵消所述第一信号处理功能; 以及将所生成的生理数据处理为与第二设备兼容。 该方法还包括向第二设备提供经处理的合成生理数据。

公开(公告)号：US20090043355A1

公开(公告)日：2009-02-12

申请号：US11835812

申请日：2007-08-08

申请人： Shelley M. Cazares ,  Haresh G. Sachanandani ,  Benjamin Ettori ,  Dan Li ,  Yanting Dong

发明人： Shelley M. Cazares ,  Haresh G. Sachanandani ,  Benjamin Ettori ,  Dan Li ,  Yanting Dong

IPC分类号： A61N1/02

CPC分类号： A61N1/37282 ,  A61B5/0031 ,  A61N1/3627 ,  A61N1/36585 ,  G06F19/00 ,  G06F19/3418 ,  G16H40/63

摘要： A system evaluates the performance of an implantable medical device, such as by using a remote external server and a user interface and stored historical physiological data of a population of congestive heart failure (CHF) patients. A processor is coupled to a patient data storage device to apply multiple algorithm variations against the same implantable physiological data from the patient to produce corresponding resulting CHF indicators. The user interface includes a display that is configured to display to a user information allowing comparison between the resulting CHF indicators from the multiple algorithm variations. The display also includes a population data selector to permit the user to select physiological data from a population that includes a different set of one or more patients or physiological data collected over a period of time from the patient. This permits optimization of an algorithm parameter or selection of a best performing algorithm.

摘要翻译： 系统评估可植入医疗装置的性能，例如通过使用远程外部服务器和用户界面以及存储充血性心力衰竭（CHF）患者群体的历史生理数据。 处理器耦合到患者数据存储装置，以对来自患者的相同的可植入生理数据应用多个算法变化，以产生相应的所得CHF指示符。 用户界面包括被配置为向用户显示信息的显示器，允许根据多个算法变化比较所得到的CHF指示符。 显示器还包括种群数据选择器，以允许用户从包括不同组的一个或多个患者或在患者的一段时间内收集的生理数据的群体中选择生理数据。 这允许优化算法参数或选择最佳执行算法。

公开(公告)号：US08271088B2

公开(公告)日：2012-09-18

申请号：US12839913

申请日：2010-07-20

申请人： Shelley M. Cazares ,  Dan Li ,  Jonathan Kwok

发明人： Shelley M. Cazares ,  Dan Li ,  Jonathan Kwok

IPC分类号： A61N1/362

CPC分类号： A61B5/0031 ,  G06F19/00

摘要： This document discusses, among other things, methods and systems for facilitating automated device programming at changeout. A method comprises receiving, from a first device, physiological data at a temporary storage device; and processing the received physiological data, wherein the processing includes determining if a first signal processing function was used by the first device and substantially offsetting the first signal processing function if the first signal processing function was used by the first device; and processing the resultant physiological data to be compatible with a second device. The method further comprising providing the processed resultant physiological data to the second device.

摘要翻译： 本文档除了其他内容之外还讨论了用于在切换时实现自动化设备编程的方法和系统。 一种方法包括从临时存储装置接收来自第一装置的生理数据; 以及处理所接收的生理数据，其中所述处理包括确定所述第一设备是否使用第一信号处理功能，并且如果所述第一设备使用所述第一信号处理功能，则基本上抵消所述第一信号处理功能; 以及将所生成的生理数据处理为与第二设备兼容。 该方法还包括向第二设备提供经处理的合成生理数据。