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1.
公开(公告)号:US20180355039A1
公开(公告)日:2018-12-13
申请号:US15758515
申请日:2016-09-16
申请人: Dana-Farber Cancer Institute, Inc. , Emory University School of Medicine , President and Fellows Harvard College
IPC分类号: C07K16/28 , C07K14/705 , A61K39/395 , A61P35/00 , A61P1/16 , A61K41/00
CPC分类号: C07K16/2818 , A61K39/3955 , A61K39/39558 , A61K41/0038 , A61K2039/505 , A61K2039/545 , A61K2039/572 , A61P1/16 , A61P35/00 , C07K14/70503 , C07K2317/73 , C07K2319/30
摘要: The present invention relates to methods of reducing liver PD-1-expressing CD8+ T cells using PD-1 Fc fusion proteins that bind Fc receptors, as well as diagnostic, prognostic, therapeutic methods and compositions related thereto.
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公开(公告)号:US11124569B2
公开(公告)日:2021-09-21
申请号:US15758515
申请日:2016-09-16
申请人: Dana-Farber Cancer Institute, Inc. , Emory University , President and Fellows of Harvard College
IPC分类号: C07K16/28 , A61K39/395 , C07K14/705 , A61P1/16 , A61P35/00 , A61K41/00 , A61K39/00
摘要: The present invention relates to methods of reducing liver PD-1-expressing CD8+ T cells using PD-1 Fc fusion proteins that bind Fc receptors, as well as diagnostic, prognostic, therapeutic methods and compositions related thereto.
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