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    REGIONAL RECONSTRUCTION AND QUANTITATIVE ASSESSMENT IN LIST MODE PET IMAGING
    1.
    发明申请
    REGIONAL RECONSTRUCTION AND QUANTITATIVE ASSESSMENT IN LIST MODE PET IMAGING 有权
    列表模式PET成像中的区域重建和定量评估

    公开(公告)号：US20120089015A1

    公开(公告)日：2012-04-12

    申请号：US13145115

    申请日：2009-12-23

    申请人： Daniel Gagnon ,  Piotr J. Maniawski

    发明人： Daniel Gagnon ,  Piotr J. Maniawski

    IPC分类号： A61B6/03 ,  A61B6/00 ,  G06K9/00

    CPC分类号： G06T11/006 ,  A61B6/037

    摘要： A method for reconstructing list mode data comprises: reconstructing all list mode data of a list mode data set (30, 160) to generate a first reconstructed image (32, 62); selecting a sub-set of the list mode data set; and reconstructing the sub-set of the list mode data set to generate an enhanced reconstructed image (84, 86). An image generation system comprises: a reconstruction module (24) configured to perform a standard reconstruction of a list mode data set to generate a standard reconstructed image (32, 62); and a re-reconstruction module (24, 70, 80, 82, 150, 152, 154) configured to perform a reconstruction other than the standard reconstruction of at least a portion of the list mode data set to generate an enhanced reconstructed image (84, 86).

    摘要翻译： 重建列表模式数据的方法包括：重建列表模式数据集（30,160）的所有列表模式数据，以生成第一重建图像（32,62）; 选择列表模式数据集的子集; 以及重建列表模式数据集的子集以生成增强的重建图像（84,86）。 一种图像生成系统包括：重建模块（24），被配置为执行列表模式数据集的标准重建以生成标准重建图像（32,62）; 以及重建重建模块（24,70,80,82,150,152,154），其被配置为执行不同于所述列表模式数据集的至少一部分的标准重建的生成增强重建图像（84 ，86）。

    Regional reconstruction and quantitative assessment in list mode PET imaging
    2.
    发明授权
    Regional reconstruction and quantitative assessment in list mode PET imaging 有权
    列表模式PET成像中的区域重建和定量评估

    公开(公告)号：US08660636B2

    公开(公告)日：2014-02-25

    申请号：US13145115

    申请日：2009-12-23

    申请人： Daniel Gagnon ,  Piotr J. Maniawski

    发明人： Daniel Gagnon ,  Piotr J. Maniawski

    IPC分类号： A61B5/00

    CPC分类号： G06T11/006 ,  A61B6/037

    摘要： A method for reconstructing list mode data comprises: reconstructing all list mode data of a list mode data set (30, 160) to generate a first reconstructed image (32, 62); selecting a sub-set of the list mode data set; and reconstructing the sub-set of the list mode data set to generate an enhanced reconstructed image (84, 86). An image generation system comprises: a reconstruction module (24) configured to perform a standard reconstruction of a list mode data set to generate a standard reconstructed image (32, 62); and a re-reconstruction module (24, 70, 80, 82, 150, 152, 154) configured to perform a reconstruction other than the standard reconstruction of at least a portion of the list mode data set to generate an enhanced reconstructed image (84, 86).

    摘要翻译： 重建列表模式数据的方法包括：重建列表模式数据集（30,160）的所有列表模式数据，以生成第一重建图像（32,62）; 选择列表模式数据集的子集; 以及重建列表模式数据集的子集以生成增强的重建图像（84,86）。 一种图像生成系统包括：重建模块（24），被配置为执行列表模式数据集的标准重建以生成标准重建图像（32,62）; 以及重建重建模块（24,70,80,82,150,152,154），其被配置为执行不同于所述列表模式数据集的至少一部分的标准重建的生成增强重建图像（84 ，86）。

    Large bore PET and hybrid PET/CT scanners and radiation therapy planning using same
    3.
    发明授权
    Large bore PET and hybrid PET/CT scanners and radiation therapy planning using same 有权
    大口径PET和混合PET / CT扫描仪和使用其的放射治疗计划

    公开(公告)号：US08063376B2

    公开(公告)日：2011-11-22

    申请号：US12535722

    申请日：2009-08-05

    申请人： Piotr J. Maniawski ,  Daniel Gagnon

    发明人： Piotr J. Maniawski ,  Daniel Gagnon

    IPC分类号： G01T1/161

    CPC分类号： A61N5/103 ,  A61B6/032 ,  A61B6/037 ,  A61B6/5235 ,  A61N5/1039 ,  A61N2005/1052 ,  A61N2005/1061 ,  G01T1/2985

    摘要： An imaging system comprises: a ring of positron emission tomography (PET) detectors; a PET housing at least partially surrounding the ring of PET detectors and defining a patient aperture of at least 80 cm; a coincidence detection processor or circuitry configured to identify substantially simultaneous 511 keV radiation detection events corresponding to electron-positron annihilation events; and a PET reconstruction processor configured to reconstruct into a PET image the identified substantially simultaneous 511 keV radiation detection events based on lines of response defined by the substantially simultaneous 511 keV radiation detection events. Radiation planning utilizing such an imaging system comprises: acquiring PET imaging data for a human subject arranged in a radiation therapy position requiring a patient aperture of at least about 80 cm; reconstructing said imaging data into a PET image encompassing an anatomical region to undergo radiation therapy; and generating a radiation therapy plan based on at least the PET image.

    摘要翻译： 成像系统包括：正电子发射断层摄影（PET）检测器环; PET壳体，其至少部分地围绕PET检测器的环并限定至少80cm的患者孔; 符合检测处理器或电路，被配置为基本上同时识别对应于电子 - 正电子湮灭事件的511keV辐射检测事件; 以及PET重建处理器，其被配置为基于由基本上同时的511keV辐射检测事件限定的响应线，将所识别的基本上同时的511keV辐射检测事件重建成PET图像。 利用这种成像系统的辐射规划包括：获取布置在放射治疗位置的人类对象的PET成像数据，其需要至少约80cm的患者孔径; 将所述成像数据重建成包含解剖区域的PET图像进行放射治疗; 以及至少基于PET图像生成放射治疗计划。

    Negativity bias reduction
    6.
    发明授权
    Negativity bias reduction 失效
    负偏差降低

    公开(公告)号：US5663566A

    公开(公告)日：1997-09-02

    申请号：US633206

    申请日：1996-04-16

    申请人： Piotr J. Maniawski ,  Stephen D. Miller

    发明人： Piotr J. Maniawski ,  Stephen D. Miller

    IPC分类号： A61B5/00 ,  G01T1/164 ,  G06T1/00 ,  G06T5/20 ,  G01T1/20

    CPC分类号： G06T5/20 ,  G01T1/1647 ,  Y10S378/901

    摘要： Radiation indicative of an object being imaged is detected and a data set indicative of the detected radiation is generated. Negative cells within the data set are located and ordered for processing. A negative cell is selected for processing. A mask region is defined in relation to the selected cell, and positive cells within the mask region are identified. A correction factor is determined, the value of the positive cells is adjusted accordingly. The value of the selected cell is also adjusted so that the count value of the data set remains constant. If the value of the selected cell is still negative, new correction factors are determined and the values of the positive cells and the selected cell are again adjusted. The process is repeated until all of the negative cells within the data set have been processed. An image indicative of the object is then generated.

    摘要翻译： 检测到指示被成像物体的辐射，并产生指示检测到的辐射的数据集。 数据集中的负数单元被定位和排序用于处理。 选择负细胞进行处理。 相对于所选择的细胞定义掩模区域，并且识别掩模区域内的阳性细胞。 确定校正因子，相应地调整阳性细胞的值。 还调整所选单元格的值，使得数据集的计数值保持不变。 如果所选单元格的值仍然为负，则确定新的校正因子，并再次调整正单元格和所选单元格的值。 重复该过程，直到数据集中的所有负细胞已被处理。 然后生成指示对象的图像。

    Methodology to optimize positioning of multi-detector gamma cameras utilizing tangential detector motion
    7.
    发明授权
    Methodology to optimize positioning of multi-detector gamma cameras utilizing tangential detector motion 失效
    使用切向检测器运动来优化多检测器伽马相机的定位的方法

    公开(公告)号：US06577890B1

    公开(公告)日：2003-06-10

    申请号：US09659436

    申请日：2000-09-08

    申请人： John M. Hayes ,  Piotr J. Maniawski ,  Stephen Miller

    发明人： John M. Hayes ,  Piotr J. Maniawski ,  Stephen Miller

    IPC分类号： A61B600

    CPC分类号： G01T1/1642 ,  A61B6/037 ,  A61B6/102 ,  A61B6/4258

    摘要： A nuclear medicine imaging device includes a plurality of detector heads (10) mounted to a movable gantry for rotation around an examination region (12). The detector heads (10) include a housing (28) which surrounds a radiation sensitive crystal (26) which converts received radiation events. A positioning mechanism on the gantry maintains a relationship between the detector heads (10) such that the housing for one detector head lies adjacent to and overlaps the housing for another detector head. During an imaging event, the gantry rotates the detector heads (10) about a region of interest (12) while radiation events are sampled. At a predetermined position relative to the area of interest, the overlapping of the detector heads is reversed.

    摘要翻译： 核医学成像装置包括安装到可移动机架的多个检测器头（10），用于围绕检查区域（12）旋转。 检测器头（10）包括围绕辐射敏感晶体（26）的壳体（28），其转换接收的辐射事件。 台架上的定位机构保持检测器头（10）之间的关系，使得用于一个检测器头的壳体邻近并与另一检测器头的壳体重叠。 在成像事件期间，在对辐射事件进行采样的同时，台架绕感兴趣区域（12）旋转检测器头（10）。 在相对于感兴趣区域的预定位置处，检测器头的重叠相反。

    Split window scatter correction
    8.
    发明授权
    Split window scatter correction 失效
    拆分窗口散射校正

    公开(公告)号：US5633500A

    公开(公告)日：1997-05-27

    申请号：US561936

    申请日：1995-11-22

    申请人： Hugh T. Morgan ,  Gary G. Jarkewicz ,  Piotr J. Maniawski ,  Stephen D. Miller

    发明人： Hugh T. Morgan ,  Gary G. Jarkewicz ,  Piotr J. Maniawski ,  Stephen D. Miller

    IPC分类号： G01T1/164 ,  G01T1/161

    CPC分类号： G01T1/1647 ,  G01T1/1642

    摘要： A method of scatter correction for use with gamma cameras includes the steps of detecting and producing a first count value indicative of gamma radiation falling within a first energy range generally associated with a radionuclide photopeak. Gamma radiation falling within second and third energy ranges is also detected and a corresponding count produced. The second and third ranges are above and below the photopeak, respectively. The location of the second and third energy ranges is determined based on the energy resolution of the gamma camera such that a predetermined percentage of the radiation falling within the second and third ranges results from primary radiation. The second and third energy ranges may be located such that they are non-contiguous with the first energy range. Based on the count of radiation falling within the second and third ranges, the scatter radiation falling within the first energy range can be estimated, and the first count value corrected. The method is suitable for use with radionuclides having multiple closely spaced photopeaks as well as with multiple widely spaced photopeaks.

    摘要翻译： 用于伽马照相机的散射校正方法包括以下步骤：检测并产生指示伽马辐射落在通常与放射性核素光峰相关联的第一能量范围内的第一计数值。 也检测到落在第二和第三能量范围内的伽马辐射，并产生相应的计数。 第二和第三范围分别在光峰之上和之下。 基于γ相机的能量分辨率来确定第二和第三能量范围的位置，使得落入第二和第三范围内的预定百分比的辐射源自初级辐射。 第二和第三能量范围可以被定位成使得它们与第一能量范围不连续。 基于落在第二和第三范围内的辐射计数，可以估计落在第一能量范围内的散射辐射，并且校正第一计数值。 该方法适用于具有多个紧密间隔的光峰的放射性核素以及多个宽间隔的光峰。