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公开(公告)号：US09801902B2
公开(公告)日：2017-10-31
申请号：US12087837
申请日：2007-01-17
CPC分类号： A61K33/00 , A61K9/0014 , A61K9/7069 , A61K45/06 , A61K47/10 , A61K47/34 , A61L15/44 , A61L26/0066 , A61L2300/114
摘要： The present invention relates to methods for removal of dead tissue from wounds or skin using topical nitric oxide donor devices and/or compositions. In one embodiment, the present invention relates to a transdermal patch device that is designed to deliver nitric oxide. In another embodiment, the present invention relates to one or more devices and/or compositions that are designed to deliver nitric oxide and optionally one or more other compounds, where such devices/compositions include, without limitation, bandages, layered bandages, adhesive bandages, transdermal patches, creams, ointments, or a any combination of two or more thereof.
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公开(公告)号：US20090215917A1
公开(公告)日：2009-08-27
申请号：US12097087
申请日：2006-12-05
申请人： Patrick John Trotter , Paul William Watt , Robert Engel , JaimeLee Iolani Rizzo , Peter Wachtel , Jason Paul Knight
发明人： Patrick John Trotter , Paul William Watt , Robert Engel , JaimeLee Iolani Rizzo , Peter Wachtel , Jason Paul Knight
CPC分类号： C08G18/2875 , C08G18/0814 , C08G2101/00
摘要： This invention relates to antimicrobial polyurethane foams and to a method of making antimicrobial polyurethane foams. The invention also relates to the use of such foams in the production of medical devices and pharmaceutical compositions.
摘要翻译： 本发明涉及抗微生物聚氨酯泡沫以及制备抗微生物聚氨酯泡沫的方法。 本发明还涉及这种泡沫在生产医疗装置和药物组合物中的用途。
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3.发明授权Measurement of cytoskeletal proteins and uses thereof in diagnosis, prognosis and therapy 有权细胞骨架蛋白的测定及其在诊断，预后和治疗中的应用公开(公告)号：US09404931B2
公开(公告)日：2016-08-02
申请号：US11608906
申请日：2006-12-11
IPC分类号： G01N33/68
CPC分类号： G01N33/6893
摘要： The present invention relates to monitoring patients for an inflammatory condition or infection (preferably wound infection) by testing an extracellular fluid such as a wound fluid for an elevated level of: (i) vimentin; (ii) a vimentin breakdown product; or (iii) a marker indicative of the presence of vimentin. The present invention provides methods of diagnosis and prognosis, wound dressings, devices (e.g. biosensors) and kits for use in such methods.
摘要翻译： 本发明涉及通过测试诸如伤口液的细胞外液体升高的水平来监测患者的炎症状况或感染（优选伤口感染）：（i）波形蛋白; （ii）波形蛋白分解产物; 或（iii）指示波形蛋白存在的标志物。 本发明提供诊断和预后的方法，伤口敷料，用于这些方法的装置（例如生物传感器）和试剂盒。
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4.发明授权Diagnosis and prognosis of wound infection by measurement of a phospholipase A2 in wound fluid 有权伤口感染的诊断和预后通过测量伤口液中的磷脂酶A2公开(公告)号：US08685639B2
公开(公告)日：2014-04-01
申请号：US11608940
申请日：2005-06-09
IPC分类号： C12Q1/00
CPC分类号： G01N33/573 , G01N2333/918
摘要： The present invention relates to the diagnosis, prognosis and/or treatment of wound infection by testing wound fluid for the presence of a marker which is present in an amount which is indicative of infection. The marker may be high molecular weight phospholipase A2 (cPLA2) or a marker which is correlated with cPLA2.
摘要翻译： 本发明涉及通过测试伤口液体以存在指示感染量的标记物的存在来诊断，预后和/或治疗伤口感染。 标记物可以是高分子量磷脂酶A2（cPLA2）或与cPLA2相关的标记物。
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