公开(公告)号：US08550799B2

公开(公告)日：2013-10-08

申请号：US13311616

申请日：2011-12-06

申请人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Giovanni Rodriguez

发明人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Giovanni Rodriguez

IPC分类号： B29C45/17 ,  B29C45/44

CPC分类号： B29C45/1701 ,  B29C37/0007 ,  B29C45/006 ,  B29C45/1753 ,  B29C45/40 ,  B29C45/42 ,  B29C2045/1797 ,  B29C2791/005

摘要： At least one of first and second mold portions defines a mold cavity to receive molten plastic and form therefrom at least one molded part, and is movable relative to the other between (i) a closed position for sealing the mold cavity or cavities and molding at least one part therein, and (ii) an open position defining a fluid passageway between the mold portions and permitting the passage of a fluid sterilant therein. A fluid sterilant source is connectable in fluid communication with the fluid passageway for introducing the sterilant therein in the open position, contacting with the sterilant the surfaces of the first and second mold portions forming the fluid passageway and located adjacent to the at least one mold cavity, but not contacting an interior surface of a molded part within the mold cavity, to sterilize the exposed mold surfaces and thereby prevent contamination of the molded part.

摘要翻译： 第一和第二模具部分中的至少一个限定了模腔以接收熔融塑料并从其形成至少一个模制部件，并且可以在（i）用于密封模腔或空腔的闭合位置和相对于另一模制部件 其中至少一部分，以及（ii）在模具部分之间限定流体通道并允许其中的流体灭菌剂通过的打开位置。 流体灭菌剂源可连接到流体通道，用于将灭菌剂在其中引入打开位置，与杀菌剂接触，形成第一和第二模具部分的形成流体通道的表面并且邻近于至少一个模腔 但是不与模腔内的模制部件的内表面接触，对暴露的模具表面进行消毒，从而防止模制部件的污染。

公开(公告)号：US08376003B2

公开(公告)日：2013-02-19

申请号：US12861354

申请日：2010-08-23

申请人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Brian Tulley ,  Jeffrey Willey

发明人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Brian Tulley ,  Jeffrey Willey

IPC分类号： B65B3/04 ,  A61J9/00

CPC分类号： A61J11/0005 ,  A61J1/1406 ,  A61J9/003 ,  A61J11/04 ,  B65D51/002

摘要： A container is provided for storing a product, such as a fat containing liquid product, and includes a body defining a chamber for receiving the product; and a container closure including a sealing portion for sealing the product within the chamber. The container closure includes a member forming a substantially fluid-tight seal between the container closure and the body; a nipple in fluid communication with the chamber that seals the chamber with respect to the ambient atmosphere during storage of the product in the chamber and that can be opened to dispense product from the chamber therethrough; and a needle penetrable and laser resealable portion that is penetrable by the needle for aseptically filling the chamber with the product, and that is thermally resealable by the application of laser radiation thereto to seal the product within the chamber.

摘要翻译： 提供容器用于储存诸如含脂肪的液体产品的产品，并且包括限定用于容纳产品的室的主体; 以及容器封闭件，其包括用于密封腔室内的产品的密封部分。 容器封闭件包括在容器封闭件和主体之间形成基本上流体密封的密封件; 与腔室流体连通的乳头，其在产品在腔室中储存期间相对于环境大气密封腔室，并且可以打开以从腔室通过其分配产品; 以及针可穿透和可激光重新密封的部分，其可由针穿透，用于用产品无菌填充腔室，并且通过施加激光辐射可热再密封以密封腔室内的产品。

公开(公告)号：US20120138186A1

公开(公告)日：2012-06-07

申请号：US13352235

申请日：2012-01-17

申请人： Daniel Py ,  Benoit Adamo ,  John Guthy

发明人： Daniel Py ,  Benoit Adamo ,  John Guthy

IPC分类号： B65B1/04

CPC分类号： B65B3/006 ,  A61L2/10 ,  A61M5/1782 ,  B29C66/80 ,  B65B3/003 ,  B65B43/00 ,  B65B51/00 ,  Y10T29/49716

摘要： An assembly includes a support and drive assembly, a first structure and a second structure. The first structure is in operable communication with and supported by the support and drive assembly. The first structure includes at least one filling or needle assembly and is adjustable to receive a plurality of filling or needle assemblies. The second structure is supported by the support and drive assembly. The second structure includes at least one seal assembly and is adjustable to receive a plurality of seal assemblies. A method includes determining a number of containers or vials that are to be filled concurrently and adjusting an assembly to include at least one filling or needle assembly and at least one seal assembly. A number of the filling or needle assemblies and the seal assemblies equals the number of containers or vials.

摘要翻译： 组件包括支撑和驱动组件，第一结构和第二结构。 第一结构与支撑和驱动组件可操作地连通并由其支撑。 第一结构包括至少一个填充物或针头组件，并且可调节以容纳多个填充物或针头组件。 第二个结构由支撑和驱动组件支撑。 第二结构包括至少一个密封组件，并且可调节以接收多个密封组件。 一种方法包括确定要同时填充的多个容器或小瓶，并且调整组件以包括至少一个填充物或针组件和至少一个密封组件。 许多填充物或针组件和密封组件等于容器或小瓶的数量。

公开(公告)号：US07874129B2

公开(公告)日：2011-01-25

申请号：US12371601

申请日：2009-02-14

申请人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  M. Jeffrey Willey

发明人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  M. Jeffrey Willey

IPC分类号： B65B3/02 ,  B65B5/02

CPC分类号： B65B3/022

摘要： Apparatus for molding and filling a device having a body defining an opening in communication with an interior chamber for receiving a substance therein, and a closure including a penetrable and resealable portion for sealing the opening and substance received in the device. A mold includes within the aseptic chamber plural mold cavities shaped to form the closure and body, and substantially sterile surfaces extending about and contiguous to the peripheries of the mold cavities. An assembly device including end-of-arm tooling having an engaging portion engageable with each of the body and closure is movable relative to the mold to engage and de-mold the substantially sterile closures and bodies from the mold cavities. Flexible barriers are coupled to the mold and the tool to substantially prevent the passage of contaminants from the molding machine and tool therethrough.

摘要翻译： 用于模制和填充具有本体的装置的装置，该主体限定与用于在其中容纳物质的内部腔室连通的开口;以及封闭件，包括用于密封容纳在装置中的开口和物质的可穿透和可重新密封的部分。 模具包括在无菌室内的多个模具腔，其形状形成封闭件和主体，以及基本上无菌的表面，其围绕并邻近模具腔的周边延伸。 包括端臂工具的组装装置具有可与主体和闭合件中的每一个接合的接合部分，其可相对于模具移动以将基本无菌的闭合件和主体与模腔接合和脱模。 柔性屏障耦合到模具和工具，以基本上防止污染物从模制机器和工具通过。

公开(公告)号：US20070283666A1

公开(公告)日：2007-12-13

申请号：US11786206

申请日：2007-04-10

申请人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Brian Tulley ,  Jeffrey Willley

发明人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Brian Tulley ,  Jeffrey Willley

IPC分类号： B65B55/02

CPC分类号： A61J11/0005 ,  A61J1/1406 ,  A61J9/003 ,  A61J11/04 ,  B65D51/002

摘要： A container is provided for storing a product, such as a fat containing liquid product, and includes a body defining a chamber for receiving the product; and a container closure including a sealing portion for sealing the product within the chamber. The container closure includes a member forming a substantially fluid-tight seal between the container closure and the body; a nipple in fluid communication with the chamber that seals the chamber with respect to the ambient atmosphere during storage of the product in the chamber and that can be opened to dispense product from the chamber therethrough; and a needle penetrable and laser resealable portion that is penetrable by the needle for aseptically filling the chamber with the product, and that is thermally resealable by the application of laser radiation thereto to seal the product within the chamber.

摘要翻译： 提供容器用于储存诸如含脂肪的液体产品的产品，并且包括限定用于容纳产品的室的主体; 以及容器封闭件，其包括用于密封腔室内的产品的密封部分。 容器封闭件包括在容器封闭件和主体之间形成基本上流体密封的密封件; 与腔室流体连通的乳头，其在产品在腔室中储存期间相对于环境大气密封腔室，并且可以打开以从腔室通过其分配产品; 以及针可穿透和可激光重新密封的部分，其可由针穿透，用于用产品无菌填充腔室，并且通过施加激光辐射可热再密封以密封腔室内的产品。

公开(公告)号：US08096333B2

公开(公告)日：2012-01-17

申请号：US12627655

申请日：2009-11-30

申请人： Daniel Py ,  Benoit Adamo ,  John Guthy

发明人： Daniel Py ,  Benoit Adamo ,  John Guthy

IPC分类号： B65B1/04

CPC分类号： B65B3/006 ,  A61L2/10 ,  A61M5/1782 ,  B29C66/80 ,  B65B3/003 ,  B65B43/00 ,  B65B51/00 ,  Y10T29/49716

摘要： An assembly includes a support and drive assembly, a first structure and a second structure. The first structure is in operable communication with and supported by the support and drive assembly. The first structure includes at least one needle assembly and is adjustable to receive a plurality of needle assemblies. The second structure is supported by the support and drive assembly. The second structure includes at least one seal assembly and is adjustable to receive a plurality of seal assemblies. A method includes determining a number of vials that are to be filled concurrently and adjusting an assembly to include at least one needle assembly and at least one seal assembly. A number of the needle assemblies and the seal assemblies equals the number of vials.

摘要翻译： 组件包括支撑和驱动组件，第一结构和第二结构。 第一结构与支撑和驱动组件可操作地连通并由其支撑。 第一结构包括至少一个针组件，并且可调节以接收多个针组件。 第二个结构由支撑和驱动组件支撑。 第二结构包括至少一个密封组件，并且可调节以接收多个密封组件。 一种方法包括确定要同时填充的小瓶的数量并且调整组件以包括至少一个针组件和至少一个密封组件。 许多针组件和密封组件等于小瓶的数量。

公开(公告)号：US07490453B2

公开(公告)日：2009-02-17

申请号：US11374522

申请日：2006-03-13

申请人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Jeffrey Willey

发明人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Jeffrey Willey

IPC分类号： B65B3/02 ,  B65B5/02

CPC分类号： B65B3/022

摘要： Apparatus for molding and filling a container having a container body defining an opening in communication with an interior chamber for receiving a substance therein, and a container closure including stopper receivable within the opening for sealing the opening and substance received in the container. A mold includes within the aseptic chamber plural mold cavities shaped to form the container closure and container body, and substantially sterile surfaces extending about and contiguous to the peripheries of the mold cavities. An assembly device including end-of-arm tooling having an engaging portion engageable with each of the container body and container closure is movable relative to the mold to engage and de-mold the substantially sterile container closure and container bodies from the mold cavities. Flexible barriers are coupled to the mold and the tool to substantially prevent the passage of contaminants from the molding machine and tool therethrough.

摘要翻译： 用于模制和填充具有容器主体的容器的装置，所述容器主体限定与用于在其中容纳物质的内部腔室连通的开口，容器封闭件包括可接收在开口内的止动件，用于密封容纳在容器中的开口和物质。 模具包括在无菌室内的多个模腔，其形状形成容器封闭件和容器主体，以及基本上无菌的表面，其围绕并邻近模具腔的周边延伸。 一种组装装置，其包括具有可与容器主体和容器封闭件中的每一个接合的接合部分的臂端工具相对于模具可移动以将基本无菌的容器封闭物和容器主体与模腔接合和脱模。 柔性屏障耦合到模具和工具，以基本上防止污染物从模制机器和工具通过。

公开(公告)号：US07410050B2

公开(公告)日：2008-08-12

申请号：US11388811

申请日：2006-03-24

申请人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Giovanni Rodriguez

发明人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Giovanni Rodriguez

IPC分类号： A45C11/04 ,  B65B1/04

CPC分类号： A45C11/005 ,  Y10S134/901

摘要： A contact lens container includes a body defining a cavity that is sized to hold a contact lens. A stopper is in fluid communication with the cavity and the stopper includes a resealable portion that is received into a channel. The resealable portion has a predetermined wall thickness in an axial direction thereof, the resealable portion defines a needle penetration region that is pierceable with a needle to form a needle aperture therethrough, and is heat resealable to hermetically seal the needle aperture.

摘要翻译： 隐形眼镜容器包括限定腔体的主体，其尺​​寸被设计成保持隐形眼镜。 止动器与空腔流体连通，并且止动件包括接收到通道中的可重新密封部分。 可重新密封的部分在其轴向上具有预定的壁厚，可重新密封部分限定了用针刺穿的针穿透区域，以形成穿过其中的针孔，并且是可热再密封的，以密封针孔。

公开(公告)号：US20060237335A1

公开(公告)日：2006-10-26

申请号：US11388811

申请日：2006-03-24

申请人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Giovanni Rodriguez

发明人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Giovanni Rodriguez

IPC分类号： A45C11/04

CPC分类号： A45C11/005 ,  Y10S134/901

摘要： A contact lens container includes a body defining a cavity that is sized to hold a contact lens. A stopper is in fluid communication with the cavity and the stopper includes a resealable portion that is received into a channel. The resealable portion has a predetermined wall thickness in an axial direction thereof, the resealable portion defines a needle penetration region that is pierceable with a needle to form a needle aperture therethrough, and is heat resealable to hermetically seal the needle aperture.

摘要翻译： 隐形眼镜容器包括限定腔体的主体，其尺​​寸被设计成保持隐形眼镜。 止动器与空腔流体连通，并且止动件包括接收到通道中的可重新密封部分。 可重新密封的部分在其轴向上具有预定的壁厚，可重新密封部分限定了用针刺穿的针穿透区域，以形成穿过其中的针孔，并且是可热再密封的，以密封针孔。

公开(公告)号：US08181431B2

公开(公告)日：2012-05-22

申请号：US13012074

申请日：2011-01-24

申请人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  M. Jeffrey Willey

发明人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  M. Jeffrey Willey

IPC分类号： B65B3/02 ,  B65B5/02

CPC分类号： B65B3/022

摘要： Apparatus for molding and filling a device having a body defining an opening in communication with an interior chamber for receiving a substance therein, and a closure including a penetrable and resealable portion for sealing the opening and substance received in the device. A mold includes within the aseptic chamber plural mold cavities shaped to form the closure and body, and substantially sterile surfaces extending about and contiguous to the peripheries of the mold cavities. An assembly device including end-of-arm tooling having an engaging portion engageable with each of the body and closure is movable relative to the mold to engage and de-mold the substantially sterile closures and bodies from the mold cavities. Flexible barriers are coupled to the mold and the tool to substantially prevent the passage of contaminants from the molding machine and tool therethrough.

摘要翻译： 用于模制和填充具有本体的装置的装置，该主体限定与用于在其中容纳物质的内部腔室连通的开口;以及封闭件，包括用于密封容纳在装置中的开口和物质的可穿透和可重新密封的部分。 模具包括在无菌室内的多个模具腔，其形状形成封闭件和主体，以及基本上无菌的表面，其围绕并邻近模具腔的周边延伸。 包括端臂工具的组装装置具有可与主体和闭合件中的每一个接合的接合部分，其可相对于模具移动以将基本无菌的闭合件和主体与模腔接合和脱模。 柔性屏障耦合到模具和工具，以基本上防止污染物从模制机器和工具通过。