公开(公告)号：US10145850B2

公开(公告)日：2018-12-04

申请号：US13000942

申请日：2009-06-18

Applicant: David Brian Galloway

Inventor： David Brian Galloway

IPC: G01N33/574 ,  G01N33/53 ,  C07K16/00

Abstract: This invention relates to a method of detecting or determining the presence of prostate cancer cells in a sample of body fluid from a subject comprising: (i) isolating cells from said sample to provide a cell sample; (ii) contacting said cell sample with a specific binding member capable of binding a prostate antigen; and/or (iii) contacting said cell sample with a specific binding member capable of binding a minichromosome maintenance (MCM) polypeptide(s); and (iv) determining the binding of said specific binding member(s) to the cell sample.

公开(公告)号：US20110184073A1

公开(公告)日：2011-07-28

申请号：US13000942

申请日：2009-06-18

Applicant: David Brian Galloway

Inventor： David Brian Galloway

IPC: A61K47/00 ,  G01N33/53 ,  A61P35/00

CPC classification number: G01N33/57434

Abstract: This invention relates to a method of detecting or determining the presence of prostate cancer cells in a sample of body fluid from a subject comprising: (i) isolating cells from said sample to provide a cell sample; (ii) contacting said cell sample with a specific binding member capable of binding a prostate antigen; and/or (iii) contacting said cell sample with a specific binding member capable of binding a minichromosome maintenance (MCM) polypeptide(s); and (iv) determining the binding of said specific binding member(s) to the cell sample.

Abstract translation: 本发明涉及一种检测或确定来自受试者的体液样品中前列腺癌细胞的存在的方法，包括：（i）从所述样品中分离细胞以提供细胞样品; （ii）使所述细胞样品与能够结合前列腺抗原的特异性结合成员接触; 和/或（iii）使所述细胞样品与能够结合微染色体维持（MCM）多肽的特异性结合成员接触; 和（iv）确定所述特异性结合成员与细胞样品的结合。