摘要:
Compounds of formula I, ##STR1## in which A is a 5 or 6 membered, fully unsaturated, carbocyclic or heterocyclic ring,B is a 5 or 6 membered, fully unsaturated, nitrogen containing heterocyclic ring,X is NR.sub.19, O or S,R.sub.19 is hydrogen or alkyl optionally substituted by --OCOR,n is 0 or 1,R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9 and R.sub.10 have various significances,R.sub.1 and R.sub.2, are hydrogen or alkyl or together with the ring carbon atoms to which they are attached, form a benzene or pyridine ring, which ring carries substituents R.sub.15, R.sub.16, R.sub.17 and R.sub.18,R.sub.15, R.sub.16, R.sub.17 and R.sub.18, have varioussignificances, with certain provisos are described.Processes for making the compounds and pharmaceutical formulations containing them, e.g. for the treatment of conditions including excess gastric acid secretion, are also described.
摘要:
There are described compounds of formula I, ##STR1## in which A is a benzene or heterocyclic ring, y is 0 or 1,L is a group containing 1 or 2 carbon atoms, or is a single bond,R.sub.9 and R.sub.10 have a variety of significances, e.g.R.sub.10 may form part of a double bond with L, orthe group --NR.sub.9 R.sub.10 forms a ring carrying substituents R.sub.1 and R.sub.8, orwhen L is a single bond --NR.sub.10 and R.sub.8 may form a ring carrying substituents R.sub.16 to R.sub.25, orthe group --LNR.sub.9 R.sub.10 forms a heterocyclic ring carrying substituents R.sub.26 to R.sub.33,R.sub.1 to R.sub.8 and R.sub.16 to R.sub.33 have a variety of significancesn is 0, 1 or 2,x is 3, 4 or 5,X is S, O or NR.sub.15,R.sub.15 is hydrogen, --COR, --COOR or alkyl optionally substituted by --OCOR,and certain provisos.Processes for making the compounds and pharmaceutical formulations containing them, e.g. for the treatment of conditions involving excess gastric acid secretion, are also described.
摘要翻译:描述了式I化合物,其中A是苯或杂环,y是0或1,L是含有1或2个碳原子的基团,或是单键,R 9和R 10具有 各种意义,例如 R 10可以与L形成双键的一部分,或者-NR 9 R 10基团形成携带取代基R 1和R 8的环,或者当L是单键-NR 10时,R 8可以形成携带取代基R 16〜R 25的环, LNR9R10形成携带取代基R26至R33的杂环,R1至R8和R16至R33具有各种含义,n为0,1或2,x为3,4或5,X为S,O或NR15,R15为氢 ,-COR,-COOR或任选被-OCOR取代的烷基,以及某些条件。 制备化合物和含有它们的药物制剂的方法,例如 也描述了治疗涉及过多胃酸分泌的病症。
摘要:
A Exercise Pool is disclosed herein having a rigid frame modular in design to allow for improved delivery and assembling. As shown the system may be configured with a box like structure providing containment of the flow head and may be configured with a removable deck having an air gap built in. As disclosed the treadmill swimming pool system as its general configuration is safer for users as it inhibits and/or eliminates hair and body entrapment. As disclosed it has a balanced flow which better replicates or reproduces actual swimming conditions for an enhanced user experience. The propulsion system may be controlled with a variable frequency drive (VFD) to allow for improved swimming conditions and control of same.
摘要:
A Exercise Pool is disclosed herein having a rigid frame modular in design to allow for improved delivery and assembling. As shown the system may be configured with a box like structure providing containment of the flow head and may be configured with a removable walk deck having an air gap built in. As disclosed the treadmill swimming pool system as its general configuration is safer for users as it inhibits and/or eliminates hair and body entrapment. As disclosed it has a balanced flow which better replicates or reproduces actual swimming conditions for an enhanced user experience. The propulsion system may be controlled with a variable frequency drive (VFD) to allow for improved swimming conditions and control of same.
摘要:
A self-contained swimming pool for containment of water and generation of water currents therein for exercise, therapy and/or rehabilitation of a user comprising a rigid frame exteriorly located in relation to an inner water containment area. A set of water return channels in communication with the inner water containment area. A propulsion system in communication with the set of water return channels and the inner water containment area. A hydraulic system for driving the propulsion system using a hydraulic fluid to produce a current in the inner water containment area allowing positioning of a user in the current for exercise, therapy and or rehabilitation therein and wherein the hydraulic system is self-contained and mounted external of the rigid frame.
摘要:
A self-contained swimming pool for containment of water and generation of water currents therein for exercise, therapy and or rehabilitation of a user comprising a rigid frame 1 exteriorly located in relation to an inner water containment area 2. A set of water return channels 3 in communication with the inner water containment area 2. A propulsion system 4 in communication with the set of water return channels 3 and the inner water containment area 2. A hydraulic system 5 for driving the propulsion system 4 using a hydraulic fluid 6 to produce a current 7 in the inner water containment area 2 allowing positioning of a user 12 in the current 7 for exercise, therapy and or rehabilitation therein and wherein the hydraulic system 5 is self-contained and mounted external of the rigid frame 1.
摘要:
A blind fastener has a nut with a threaded bore, a core bolt having external threads for receipt by the nut, and a sleeve for expansion by the head of the core bolt and a shoulder of the nut to form a blind side folded bulb against the backside sheet of a joint. A thin-walled, tapered section of the sleeve fits over a relieved section of the nut and bears against the shoulder of the nut. The taper is such that the thin wall increases in thickness away from the shoulder. An axially adjacent thick-walled section of the sleeve bears on the core bolt head and resists sleeve tuck-out over the core bolt head, concentrically aligns the sleeve on the core bolt, and assures that the thin-walled section of the sleeve is the section that bulbs. During setting, the sleeve expands by compression exerted on it by the core bolt head and the shoulder. The thin wall section folds against the backside sheet with an ever-increasing area as tightening continues. The fold always develops against the backside sheet because the portion of the sleeve free of the sheet is weakest in compression there. Axial clamp-up force is spread over a large area of the sheet but unit loading is low.
摘要:
A self-contained swimming pool for containment of water and generation of water currents therein for exercise, therapy and/or rehabilitation of a user comprising a rigid frame exteriorly located in relation to an inner water containment area. A set of water return channels in communication with the inner water containment area. A propulsion system in communication with the set of water return channels and the inner water containment area. A hydraulic system for driving the propulsion system using a hydraulic fluid to produce a current in the inner water containment area allowing positioning of a user in the current for exercise, therapy and or rehabilitation therein and wherein the hydraulic system is self-contained and mounted external of the rigid frame.
摘要:
A modular vehicle and an associated method of constructing a modular vehicle are provided. A modular vehicle includes a chassis and a plurality of docking fixtures carried by the chassis. The docking fixtures may include an electrical power connection and optionally a fluid connection. The docking fixtures may provide for data communications via data communication connections or via the electrical power connections. The modular vehicle may also include a plurality of modules removably connected to respective ones of the docking fixtures. The plurality of modules may include at least one of an energy supply module an energy storage module or a cooling module. At least one module may include an electrical power connection coupled to the electrical power connection of a docking fixture and optionally a fluid connection coupled to the fluid connection of a docking fixture. At least one module may also provide for data communications with a docking fixture.