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公开(公告)号：US20200061008A1
公开(公告)日：2020-02-27
申请号：US16107621
申请日：2018-08-21
申请人： David Michael Ott
发明人： David Michael Ott
摘要： The present disclosure relates to the use of lipophilic mercaptans for the treatment of pain sensitization. The lipophilic mercaptans disclosed can be used to decrease the formation of protein-aldehyde adducts within nociceptive nerves, thereby reducing sensitization to pain.
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公开(公告)号：US09968580B2
公开(公告)日：2018-05-15
申请号：US15251880
申请日：2016-08-30
申请人： David Michael Ott
发明人： David Michael Ott
CPC分类号： A61K31/22 , A23L33/10 , A23V2002/00 , A61K9/4858 , A61K31/19
摘要： Genetic and epigenetic diseases and disorders are treated with FDA approved dietary compositions in the form of dietary supplements and nutraceuticals. The diseases and disorders to be treated include Rett syndrome, trinucleotide repeat diseases such as Fragile X syndrome, memory impairment, chronic inflammation, pre-cancerous conditions which involve cancer stem cells, and post-cancerous conditions which involve cancer stem cells which have survived in spite of cancer treatment. Treatment options include prophylactic treatment which is initiated prior to the development of the symptoms of the disease or disorder.
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公开(公告)号：US20180228756A1
公开(公告)日：2018-08-16
申请号：US15950877
申请日：2018-04-11
申请人： David Michael Ott
发明人： David Michael Ott
CPC分类号： A61K31/22 , A23L33/10 , A23V2002/00 , A61K9/4858 , A61K31/19
摘要： Genetic and epigenetic diseases and disorders are treated with FDA approved dietary compositions in the form of dietary supplements and nutraceuticals. The diseases and disorders to be treated include Rett syndrome, trinucleotide repeat diseases such as Fragile X syndrome, memory impairment, chronic inflammation, pre-cancerous conditions which involve cancer stem cells, and post-cancerous conditions which involve cancer stem cells which have survived in spite of cancer treatment. Treatment options include prophylactic treatment which is initiated prior to the development of the symptoms of the disease or disorder.
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公开(公告)号：US20170100349A1
公开(公告)日：2017-04-13
申请号：US15387181
申请日：2016-12-21
申请人： David Michael Ott
发明人： David Michael Ott
CPC分类号： A61K31/10 , A23L33/10 , A61K9/48 , A61K31/198 , A61K33/06 , A61K47/542 , C07C319/24 , C07C323/59 , A61K2300/00
摘要： Divalent salts of S-allylmercapto-N-acetylcysteine and related compositions are disclosed which can be administered in order to provide protection from the formation of aldehyde-protein adducts, protein carbonylation, protein aggregation, and the resulting neuroinflammation. Various neurodegenerative diseases which are suitable for treatment using these compositions include Alzheimer's disease, senile dementia, Parkinson's disease, multiple sclerosis, Lewy body disease, peripheral neuropathy, spinal cord injury, stroke and cerebral ischemia.
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5.发明申请METHOD OF DIETARY TREATMENT FOR GENETIC AND EPIGENETIC DISEASES AND DISORDERS 审中-公开用于遗传和感染性疾病和疾病的膳食治疗方法公开(公告)号：US20170056357A1
公开(公告)日：2017-03-02
申请号：US15251880
申请日：2016-08-30
申请人： David Michael Ott
发明人： David Michael Ott
CPC分类号： A61K31/22 , A23L33/10 , A23V2002/00 , A61K9/4858 , A61K31/19
摘要： Genetic and epigenetic diseases and disorders are treated with FDA approved dietary compositions in the form of dietary supplements and nutraceuticals. The diseases and disorders to be treated include Rett syndrome, trinucleotide repeat diseases such as Fragile X syndrome, memory impairment, chronic inflammation, pre-cancerous conditions which involve cancer stem cells, and post-cancerous conditions which involve cancer stem cells which have survived in spite of cancer treatment. Treatment options include prophylactic treatment which is initiated prior to the development of the symptoms of the disease or disorder.
摘要翻译： 遗传和表观遗传疾病和病症以FDA批准的饮食组合物以膳食补充剂和营养品的形式进行治疗。 待治疗的疾病和病症包括Rett综合征，三核苷酸重复疾病如脆性X综合征，记忆障碍，慢性炎症，涉及癌症干细胞的癌前病症，以及涉及癌症干细胞的癌后病症 尽管癌症治疗。 治疗方案包括在发展疾病或病症症状之前开始的预防性治疗。
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6.发明申请公开(公告)号：US20140050677A1
公开(公告)日：2014-02-20
申请号：US13998297
申请日：2013-10-19
申请人： David Michael Ott
发明人： David Michael Ott
IPC分类号： A61K8/46 , A61K31/198 , A61Q19/00
CPC分类号： A61K8/46 , A61K8/97 , A61K31/198 , A61Q11/00 , A61Q19/00
摘要： Personal care products useful for the maintenance of personal appearance and good health and minor treatments that do not require professional health care, as well as products that provide a combination of anti-oxidant, anti-inflammatory, antimicrobial, and anti-aging properties and are suitable for use without a prescription. The products utilize biomembrane permeable organosulfur compounds that can redox cycle between thiol, disulfide, and thiosulfinate forms in response to antioxidants and oxidants that are inside and outside of cells. Example products include an antioxidant skin lotion with anti-inflammatory, antimicrobial, anti-arsenicosis, anti-aging, and deodorant properties.
摘要翻译： 个人护理产品有助于维护个人外观和良好的健康状况以及不需要专业保健的微小治疗，以及提供抗氧化剂，抗炎，抗微生物和抗衰老性能组合的产品， 适合无处方使用。 该产品利用生物膜可渗透的有机硫化合物，其响应于细胞内部和外部的抗氧化剂和氧化剂，可以在硫醇，二硫键和硫代亚磺酸盐形式之间进行氧化还原循环。 示例产品包括具有抗炎，抗微生物，抗砷，抗衰老和除臭性能的抗氧化皮肤乳液。
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7.发明申请Organosulfur Compounds for the Prevention and Treatment of Neurodegenerative Diseases 有权用于预防和治疗神经退行性疾病的有机硫化合物公开(公告)号：US20130165515A1
公开(公告)日：2013-06-27
申请号：US13694447
申请日：2012-12-03
申请人： David Michael Ott
发明人： David Michael Ott
IPC分类号： C07C323/59 , C07C319/24
CPC分类号： A61K31/10 , A23L33/10 , A61K9/48 , A61K31/198 , A61K33/06 , A61K47/542 , C07C319/24 , C07C323/59 , A61K2300/00
摘要： Divalent salts of S-allylmercapto-N-acetylcysteine and related compositions are disclosed which can be administered in order to provide protection from the formation of aldehyde-protein adducts, protein carbonylation, protein aggregation, and the resulting neuroinflammation. Various neurodegenerative diseases which are suitable for treatment using these compositions include Alzheimer's disease, senile dementia, Parkinson's disease, multiple sclerosis, Lewy body disease, peripheral neuropathy, spinal cord injury, stroke and cerebral ischemia.
摘要翻译： 公开了S-烯丙基巯基-N-乙酰半胱氨酸和相关组合物的二价盐，其可以被施用以提供保护免于形成醛 - 蛋白质加合物，蛋白质羰基化，蛋白质聚集和所产生的神经炎症。 适用于使用这些组合物治疗的各种神经变性疾病包括阿尔茨海默氏病，老年性痴呆，帕金森病，多发性硬化，路易体病，周围神经病，脊髓损伤，中风和脑缺血。
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公开(公告)号：US11026911B2
公开(公告)日：2021-06-08
申请号：US16555885
申请日：2019-08-29
申请人： David Michael Ott
发明人： David Michael Ott
摘要： Genetic and epigenetic diseases and disorders are treated with FDA approved dietary compositions in the form of dietary supplements and nutraceuticals. The diseases and disorders to be treated include Rett syndrome, trinucleotide repeat diseases such as Fragile X syndrome, memory impairment, chronic inflammation, pre-cancerous conditions which involve cancer stem cells, and post-cancerous conditions which involve cancer stem cells which have survived in spite of cancer treatment. Treatment options include prophylactic treatment which is initiated prior to the development of the symptoms of the disease or disorder.
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公开(公告)号：US10258581B2
公开(公告)日：2019-04-16
申请号：US15387181
申请日：2016-12-21
申请人： David Michael Ott
发明人： David Michael Ott
IPC分类号： A61K9/48 , A61K31/10 , A61K33/06 , A61K47/54 , A61K31/198 , C07C323/59 , C07C319/24 , A23L33/10
摘要： Divalent salts of S-allylmercapto-N-acetylcysteine and related compositions are disclosed which can be administered in order to provide protection from the formation of aldehyde-protein adducts, protein carbonylation, protein aggregation, and the resulting neuroinflammation. Various neurodegenerative diseases which are suitable for treatment using these compositions include Alzheimer's disease, senile dementia, Parkinson's disease, multiple sclerosis, Lewy body disease, peripheral neuropathy, spinal cord injury, stroke and cerebral ischemia.
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10.发明申请公开(公告)号：US20190076377A1
公开(公告)日：2019-03-14
申请号：US16186077
申请日：2018-11-09
申请人： David Michael Ott
发明人： David Michael Ott
IPC分类号： A61K31/10 , A61K47/54 , A61K9/48 , A23L33/10 , A61K31/198 , C07C319/24 , C07C323/59
摘要： Divalent salts of S-allylmercapto-N-acetylcysteine and related compositions are disclosed which can be administered in order to provide protection from the formation of aldehyde-protein adducts, protein carbonylation, protein aggregation, and the resulting neuroinflammation. Various neurodegenerative diseases which are suitable for treatment using these compositions include Alzheimer's disease, senile dementia, Parkinson's disease, multiple sclerosis, Lewy body disease, peripheral neuropathy, spinal cord injury, stroke and cerebral ischemia.
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