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公开(公告)号:US06261793B1
公开(公告)日:2001-07-17
申请号:US09262749
申请日:1999-03-04
申请人: David Whyte , Marnie McGuirk , Irma Nuñez-Oliva , Tish Hockenberry , James Pai
发明人: David Whyte , Marnie McGuirk , Irma Nuñez-Oliva , Tish Hockenberry , James Pai
IPC分类号: C12Q148
CPC分类号: C12N9/6421 , C12Q1/37 , G01N2500/00
摘要: The present invention provides human ras converting endoprotease (RCE), the encoding nucleic acids, recombinant vectors, transformed host cells and methods of making human RCE. More particularly, the invention provides methods of using human RCE in screening systems to identify inhibitors of human RCE useful for the treatment of various medical conditions. This invention further relates to inhibitors of human RCE.
摘要翻译: 本发明提供人ras转化内蛋白酶(RCE),编码核酸,重组载体,转化的宿主细胞和制备人RCE的方法。 更具体地,本发明提供了使用人RCE在筛选系统中鉴定可用于治疗各种医学病症的人RCE抑制剂的方法。 本发明还涉及人类RCE的抑制剂。