METHOD OF PREVENTION AND ALLEVIATION OF TOXICITY BY MODULATION OF IRF3
    3.
    发明申请
    METHOD OF PREVENTION AND ALLEVIATION OF TOXICITY BY MODULATION OF IRF3 审中-公开
    通过IRF3调节预防和治疗毒性的方法

    公开(公告)号:US20090181910A1

    公开(公告)日:2009-07-16

    申请号:US11867589

    申请日:2007-10-04

    摘要: The invention provides compounds, compositions, animal models, drug screening methods, pharmaceutical compositions, and methods of treatment which relate to the modulation of the metabolism of xenobiotic compounds by administering agents which act on IRF3 or an IRF3 control pathway to modulate the activity, expression, or levels of cytochrome P450 enzymes involved in the metabolism of xenobiotic compounds in a subject.

    摘要翻译: 本发明提供化合物,组合物,动物模型,药物筛选方法,药物组合物和治疗方法,这些方法涉及通过施用于IRF3或IRF3对照途径以调节活性,表达的施用试剂对异生物化合物的代谢的调节 ,或参与受试者中异种生物化合物代谢的细胞色素P450酶水平。