公开(公告)号：US08945448B2

公开(公告)日：2015-02-03

申请号：US13491385

申请日：2012-06-07

申请人： Derek Rinderknecht ,  Hasham Azizgolshani ,  Mortez Gharib

发明人： Derek Rinderknecht ,  Hasham Azizgolshani ,  Mortez Gharib

IPC分类号： B29C39/10 ,  B29C39/12

CPC分类号： A61M5/14276 ,  A61M5/14224 ,  A61M37/00 ,  A61M2205/8206 ,  A61M2205/8212 ,  A61M2205/8243 ,  A61M2207/00 ,  A61M2210/0612 ,  A61M2210/0662 ,  A61M2210/0693 ,  G01F11/08

摘要： Described herein are systems, devices, and methods for the delivery of substances to, or the sampling of substances from, a patient using a portable and preferably implantable device. The substances introduced to and/or taken from the patient are preferably fluidic and are driven by a miniature pump, such as a microimpedance pump. A number of design variations are explicitly and implicitly described, such as the use of multiple pumps and multiple reservoirs for containing medicaments. Methods of manufacture of these systems and devices are also described, for instance, using molding, micromachining, or lithographic processes.

摘要翻译： 本文描述了用于使用便携式和优选可植入装置向患者输送物质或从其中取样物质的系统，装置和方法。 引入和/或从患者取出的物质优选是流体性的，并且由诸如微阻抗泵的微型泵驱动。 明确和隐含地描述了许多设计变化，例如使用多个泵和多个储存器来容纳药物。 还描述了这些系统和装置的制造方法，例如使用成型，微加工或光刻工艺。

公开(公告)号：US20130041319A1

公开(公告)日：2013-02-14

申请号：US13491385

申请日：2012-06-07

申请人： Derek Rinderknecht ,  Hasham Azizgolshani ,  Mortez Gharib

发明人： Derek Rinderknecht ,  Hasham Azizgolshani ,  Mortez Gharib

IPC分类号： A61M5/142

CPC分类号： A61M5/14276 ,  A61M5/14224 ,  A61M37/00 ,  A61M2205/8206 ,  A61M2205/8212 ,  A61M2205/8243 ,  A61M2207/00 ,  A61M2210/0612 ,  A61M2210/0662 ,  A61M2210/0693 ,  G01F11/08

摘要： Described herein are systems, devices, and methods for the delivery of substances to, or the sampling of substances from, a patient using a portable and preferably implantable device. The substances introduced to and/or taken from the patient are preferably fluidic and are driven by a miniature pump, such as a microimpedance pump. A number of design variations are explicitly and implicitly described, such as the use of multiple pumps and multiple reservoirs for containing medicaments. Methods of manufacture of these systems and devices are also described, for instance, using molding, micromachining, or lithographic processes.

摘要翻译： 本文描述了用于使用便携式和优选可植入装置向患者输送物质或从其中取样物质的系统，装置和方法。 引入和/或从患者取出的物质优选是流体性的，并且由微型泵例如微阻抗泵驱动。 明确和隐含地描述了许多设计变化，例如使用多个泵和多个储存器来容纳药物。 还描述了这些系统和装置的制造方法，例如使用成型，微加工或光刻工艺。

公开(公告)号：US20110301418A1

公开(公告)日：2011-12-08

申请号：US13087202

申请日：2011-04-14

申请人： Mortez Gharib ,  Jian Lu ,  David Jeon

发明人： Mortez Gharib ,  Jian Lu ,  David Jeon

IPC分类号： A61B1/07

CPC分类号： A61B5/0073 ,  A61B5/0044 ,  A61B5/6852

摘要： A catheter based defocusing imaging system for 3-D tomography reconstruction of endovascular features of interest is disclosed. Without limitation, target sites for imaging include heart valves, calcified heart valves, calcium plastered valve on the heart valve or plaque on the inner wall of the blood vessel of a patient.

摘要翻译： 公开了一种用于感兴趣的血管内特征的3-D层析成像重建的基于导管的散焦成像系统。 不限于此，用于成像的目标部位包括心脏瓣膜，钙化心脏瓣膜，心脏瓣膜上的钙质贴壁或患者血管内壁上的斑块。