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公开(公告)号：US10426743B2
公开(公告)日：2019-10-01
申请号：US16255121
申请日：2019-01-23
发明人： Sujatha D. Sonti , Joey Roger Thomas , Jon Lenn , Leandro Santos , Justin Whiteman , Michael Quinn Doherty , Mary Bedard , Piyush Jain
IPC分类号： A61K9/107 , A61K47/44 , A61K31/05 , A61K9/00 , A61K9/113 , A61K9/06 , A61K47/06 , A61K47/08 , A61K47/10 , A61K47/22
摘要： The present invention relates to topical pharmaceutical emulsion compositions comprising a therapeutically effective amount of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a pharmaceutically acceptable salt thereof, an oil phase, a water phase, a surfactant, and an antioxidant, and wherein the emulsion composition is homogeneous and/or the active is solubilized in the oil phase. The invention also relates to methods of treating a dermatological condition or disorder in a patient by administering the present compositions to the skin of the patient.
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公开(公告)号：US11612573B2
公开(公告)日：2023-03-28
申请号：US16587833
申请日：2019-09-30
发明人： Sujatha D. Sonti , Joey Roger Thomas , Jon Lenn , Leandro Santos , Justin Whiteman , Michael Doherty , Mary Bedard , Piyush Jain
IPC分类号： A61K9/00 , A61K9/107 , A61K47/06 , A61K47/44 , A61K31/05 , A61K9/113 , A61K9/06 , A61K47/08 , A61K47/10 , A61K47/22
摘要： The present invention relates to topical pharmaceutical emulsion compositions comprising a therapeutically effective amount of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a pharmaceutically acceptable salt thereof, an oil phase, a water phase, a surfactant, and an antioxidant, and wherein the emulsion composition is homogeneous and/or the active is solubilized in the oil phase. The invention also relates to methods of treating a dermatological condition or disorder in a patient by administering the present compositions to the skin of the patient.
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公开(公告)号：US10195160B2
公开(公告)日：2019-02-05
申请号：US15158858
申请日：2016-05-19
发明人： Sujatha D. Sonti , Joey Roger Thomas , Jon Lenn , Leandro Santos , Justin Whiteman , Michael Quinn Doherty , Mary Bedard , Piyush Jain
IPC分类号： A61K9/00 , A61K47/06 , A61K9/107 , A61K31/05 , A61K9/113 , A61K9/06 , A61K47/08 , A61K47/10 , A61K47/22 , A61K47/44
摘要： The present invention relates to topical pharmaceutical emulsion compositions comprising a therapeutically effective amount of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a pharmaceutically acceptable salt thereof, an oil phase, a water phase, a surfactant, and an antioxidant, and wherein the emulsion composition is homogeneous and/or the active is solubilized in the oil phase. The invention also relates to methods of treating a dermatological condition or disorder in a patient by administering the present compositions to the skin of the patient.
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公开(公告)号：US11622945B2
公开(公告)日：2023-04-11
申请号：US16229145
申请日：2018-12-21
发明人： Sujatha D. Sonti , Joey Roger Thomas , Jon Lenn , Leandro Santos , Justin Whiteman , Michael Quinn Doherty , Mary Bedard , Piyush Jain
IPC分类号： A61K9/00 , A61K9/107 , A61K9/06 , A61K47/10 , A61K47/44 , A61K31/05 , A61K9/113 , A61K47/06 , A61K47/08 , A61K47/22
摘要： The present invention relates to topical pharmaceutical emulsion compositions comprising a therapeutically effective amount of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a pharmaceutically acceptable salt thereof, an oil phase, a water phase, a surfactant, and an antioxidant, and wherein the emulsion composition is homogeneous and/or the active is solubilized in the oil phase. The invention also relates to methods of treating a dermatological condition or disorder in a patient by administering the present compositions to the skin of the patient.
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公开(公告)号：US11617724B2
公开(公告)日：2023-04-04
申请号：US15807682
申请日：2017-11-09
发明人： Sujatha D. Sonti , Joey Roger Thomas , Jon Lenn , Leandro Santos , Justin Whiteman , Michael Quinn Doherty , Mary Bedard , Piyush Jain
IPC分类号： A61K9/107 , A61K9/06 , A61K9/00 , A61K47/26 , A61K47/06 , A61K47/14 , A61K9/10 , A61K31/05 , A61K47/10 , A61K9/113
摘要： The present invention relates to topical pharmaceutical emulsion compositions comprising a therapeutically effective amount of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a pharmaceutically acceptable salt thereof, an oil phase, a water phase, a surfactant, and an antioxidant, and wherein the emulsion composition is homogeneous and/or the active is solubilized in the oil phase. The invention also relates to methods of treating a dermatological condition or disorder in a patient by administering the present compositions to the skin of the patient.
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公开(公告)号：US11458108B2
公开(公告)日：2022-10-04
申请号：US16229080
申请日：2018-12-21
发明人： Sujatha D. Sonti , Joey Roger Thomas , Jon Lenn , Leandro Santos , Justin Whiteman , Michael Quinn Doherty , Mary Bedard , Piyush Jain
IPC分类号： A61K9/107 , A61K47/06 , A61K47/44 , A61K31/05 , A61K9/00 , A61K9/113 , A61K9/06 , A61K47/08 , A61K47/10 , A61K47/22
摘要： The present invention relates to topical pharmaceutical emulsion compositions comprising a therapeutically effective amount of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a pharmaceutically acceptable salt thereof, an oil phase, a water phase, a surfactant, and an antioxidant, and wherein the emulsion composition is homogeneous and/or the active is solubilized in the oil phase. The invention also relates to methods of treating a dermatological condition or disorder in a patient by administering the present compositions to the skin of the patient.
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