公开(公告)号：US20070138692A1

公开(公告)日：2007-06-21

申请号：US11555133

申请日：2006-10-31

申请人： James Ford ,  Diana Zanini ,  Karen Altheim

发明人： James Ford ,  Diana Zanini ,  Karen Altheim

IPC分类号： B29C71/02 ,  C08J5/00

CPC分类号： B29D11/00134 ,  A61L27/18 ,  G02B1/043 ,  C08L83/04 ,  C08L51/085

摘要： The present invention is a process for forming ophthalmic devices such as contact lenses, comprising at least one silicone containing component, at least one hydrophilic component, at least one hydrophilic polymer and at least one diluent with a Hansen solubility parameter of about 2 to about 7. The processing of the ophthalmic device may be done using only aqueous solutions.

摘要翻译： 本发明是用于形成眼科装置如隐形眼镜的方法，其包括至少一种含硅氧烷的组分，至少一种亲水组分，至少一种亲水性聚合物和至少一种稀释剂，汉森溶解度参数为约2至约7 眼科装置的处理可以仅使用水溶液进行。

公开(公告)号：US20080103231A1

公开(公告)日：2008-05-01

申请号：US11874313

申请日：2007-10-18

申请人： Diana Zanini ,  Karen Altheim

发明人： Diana Zanini ,  Karen Altheim

IPC分类号： C08L43/04

CPC分类号： B29D11/00125 ,  G02B1/043 ,  C08L83/04

摘要： The present invention is a process for forming ophthalmic devices such as contact lenses, comprising the steps of curing a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component and at least one protonated diluent or protonatable diluent having a Hansen solubility parameter, δp between about 2 and about 7 to form an ophthalmic device having an advancing contact angle of less than about 80°; contacting the ophthalmic device with an aqueous solution which is capable of changing the Hansen solubility parameter, δp of the protonated or protonatable co-diluent to enhance water solubility and removing said diluent(s) with said aqueous solution.

摘要翻译： 本发明是用于形成眼科装置如隐形眼镜的方法，包括以下步骤：固化包含至少一种含硅氧烷的组分，至少一种亲水组分和至少一种质子化稀释剂或可质子化的稀释剂的反应性混合物，其具有Hansen溶解度 参数，约2至约7之间的差异，以形成具有小于约80°的前进接触角的眼科装置; 使眼科装置与水溶液接触，该水溶液能够改变Hansen溶解度参数，质子化或可质子化的共稀释剂的去除，以增强水溶性并用所述水溶液除去所述稀释剂。

公开(公告)号：US08507577B2

公开(公告)日：2013-08-13

申请号：US11874313

申请日：2007-10-18

申请人： Diana Zanini ,  Karen Altheim

发明人： Diana Zanini ,  Karen Altheim

IPC分类号： G02B1/04 ,  C08F290/06 ,  G02C7/04

CPC分类号： B29D11/00125 ,  G02B1/043 ,  C08L83/04

摘要： The present invention is a process for forming ophthalmic devices such as contact lenses, comprising the steps of curing a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component and at least one protonated diluent or protonatable diluent having a Hansen solubility parameter, δp between about 2 and about 7 to form an ophthalmic device having an advancing contact angle of less than about 80°; contacting the ophthalmic device with an aqueous solution which is capable of changing the Hansen solubility parameter, δp of the protonated or protonatable co-diluent to enhance water solubility and removing said diluent(s) with said aqueous solution.

摘要翻译： 本发明是用于形成眼科装置如隐形眼镜的方法，包括以下步骤：固化包含至少一种含硅氧烷的组分，至少一种亲水组分和至少一种质子化稀释剂或可质子化的稀释剂的反应性混合物，其具有Hansen溶解度 参数，约2至约7之间的差异，以形成具有小于约80°的前进接触角的眼科装置; 使眼科装置与水溶液接触，该水溶液能够改变Hansen溶解度参数，质子化或可质子化的共稀释剂的去除，以增强水溶性并用所述水溶液除去所述稀释剂。

公开(公告)号：US20100081772A1

公开(公告)日：2010-04-01

申请号：US12241468

申请日：2008-09-30

申请人： Diana Zanini ,  Karen Altheim

发明人： Diana Zanini ,  Karen Altheim

IPC分类号： C08L83/06 ,  C08G77/06 ,  C08G77/18 ,  C08L33/10 ,  C08L39/06 ,  C08L43/04

CPC分类号： G02B1/043 ,  B29D11/00134 ,  C08L51/085 ,  C08L43/04

摘要： The present invention relates to a process comprising the steps of reacting a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component, and at least one diluent to form an ophthalmic device having an advancing contact angle of less than about 80°; and contacting the ophthalmic device with an aqueous extraction solution at an elevated extraction temperature, wherein said at least one diluent has a boiling point at least about 10° higher than said extraction temperature.

摘要翻译： 本发明涉及一种方法，其包括以下步骤：使包含至少一种含硅氧烷的组分，至少一种亲水组分和至少一种稀释剂的反应性混合物反应以形成具有小于约80的前进接触角的眼科装置 °; 并且在升高的提取温度下使眼科装置与水提取溶液接触，其中所述至少一种稀释剂的沸点比所述提取温度高至少约10°。