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公开(公告)号:US09427229B2
公开(公告)日:2016-08-30
申请号:US12209955
申请日:2008-09-12
申请人: Donald Gonazles , Roger Pisarnwongs , Tom Weisel , Jeff Wrana
发明人: Donald Gonazles , Roger Pisarnwongs , Tom Weisel , Jeff Wrana
IPC分类号: A61B17/10 , A61B17/068 , A61B17/064 , A61B17/04
CPC分类号: A61B17/068 , A61B17/064 , A61B17/24 , A61B2017/0445 , A61B2017/0647
摘要: A system and method for inserting an implant into soft tissue. The system may include an elongate arm having an implant at a first end of the elongate arm and an actuator at a second end of the elongate arm. The implants may be contained in a cartridge assembly. Methods of inserting an implant may be used during nasal septum reconstruction.
摘要翻译: 用于将植入物插入软组织的系统和方法。 该系统可以包括细长臂,其具有在细长臂的第一端处的植入物和在细长臂的第二端处的致动器。 植入物可以包含在盒组件中。 在鼻中隔重建期间可以使用插入植入物的方法。
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公开(公告)号:US20090099577A1
公开(公告)日:2009-04-16
申请号:US12209955
申请日:2008-09-12
申请人: Donald Gonzales , Roger Pisarnwongs , Tom Weisel , Jeff Wrana
发明人: Donald Gonzales , Roger Pisarnwongs , Tom Weisel , Jeff Wrana
CPC分类号: A61B17/068 , A61B17/064 , A61B17/24 , A61B2017/0445 , A61B2017/0647
摘要: A system and method for inserting an implant into soft tissue. The system may include an elongate arm having an implant at a first end of the elongate arm and an actuator at a second end of the elongate arm. The implants may be contained in a cartridge assembly. Methods of inserting an implant may be used during nasal septum reconstruction.
摘要翻译: 用于将植入物插入软组织的系统和方法。 该系统可以包括细长臂,其具有在细长臂的第一端处的植入物和在细长臂的第二端处的致动器。 植入物可以包含在盒组件中。 在鼻中隔重建期间可以使用插入植入物的方法。
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公开(公告)号:US20110257893A1
公开(公告)日:2011-10-20
申请号:US13123138
申请日:2009-10-09
申请人: Ian Taylor , Jeff Wrana
发明人: Ian Taylor , Jeff Wrana
IPC分类号: G06F19/00
摘要: Methods for classifying samples are based on alterations in network modularity. The methods are useful for the diagnosis, prognosis and monitoring of a biological state such as a disease state. In certain embodiments, methods for diagnosing disease or evaluating the prognosis of disease or identification of a disease state are computer-implemented.
摘要翻译: 分类样本的方法是基于网络模块化的改变。 该方法对于疾病状态等生物学状态的诊断,预后和监测是有用的。 在某些实施例中,计算机实现用于诊断疾病或评估疾病预后或疾病状态识别的方法。
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公开(公告)号:US20060099645A1
公开(公告)日:2006-05-11
申请号:US10526733
申请日:2003-09-05
申请人: Jeff Wrana , Miriam Barrios-Rodiles
发明人: Jeff Wrana , Miriam Barrios-Rodiles
IPC分类号: G01N33/53
CPC分类号: C40B30/04 , C12N15/1055 , C12Q1/66 , G01N33/5008 , G01N33/502 , G01N33/6845
摘要: The invention relates to methods and reagents for screening, identifying, and/or quantifying molecular interactions. In particular, the invention provides a method for identifying protein-protein interactions comprising prey proteins interacting with bait proteins comprising: (a) introducing one or more prey protein in cells, wherein a prey protein is labelled with an epitope tag permitting separation of the prey protein from other proteins in the cells; (b) introducing one or more bait protein in the cells, wherein a bait protein is labelled with a detectable substance permitting detection of protein-protein interactions comprising a prey protein and the bait protein; and (c) assaying for protein-protein interactions comprising a prey protein and bait protein by detecting the detectable substance.
摘要翻译: 本发明涉及用于筛选,鉴定和/或定量分子相互作用的方法和试剂。 特别地,本发明提供了一种用于鉴定蛋白质 - 蛋白质相互作用的方法,其包括与诱饵蛋白相互作用的猎物蛋白质,其包括:(a)在细胞中引入一种或多种猎物蛋白质,其中猎物蛋白用允许猎物分离的表位标签 细胞中其他蛋白质的蛋白质; (b)在细胞中引入一种或多种诱饵蛋白质,其中诱饵蛋白质用可检测物质进行标记,其允许检测包含猎物蛋白质和诱饵蛋白质的蛋白质 - 蛋白质相互作用; 和(c)通过检测可检测物质来测定包含猎物蛋白质和诱饵蛋白质的蛋白质 - 蛋白质相互作用。
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