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公开(公告)号:US08765948B2
公开(公告)日:2014-07-01
申请号:US12741819
申请日:2008-11-07
申请人: Donald J. Gallagher , Laszlo R. Treiber , Robert Michael Hughes , Onorato Campopiano , Peng Wang , Yuxin Zhao , Michael Allen Ouellette , Donald Nicholas Hettinger , Helen Chou
发明人: Donald J. Gallagher , Laszlo R. Treiber , Robert Michael Hughes , Onorato Campopiano , Peng Wang , Yuxin Zhao , Shine K. Chou , Michael Allen Ouellette , Donald Nicholas Hettinger
IPC分类号: C07D239/02
CPC分类号: C07D239/54 , C07D239/553
摘要: The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.
摘要翻译: 本发明涉及用于制备结构(VI)的促性腺激素释放激素(GnRH)受体拮抗剂的方法和中间体; 及其立体异构体及其药学上可接受的盐。
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公开(公告)号:US20110098472A1
公开(公告)日:2011-04-28
申请号:US12741819
申请日:2008-11-07
申请人: Donald J. Gallagher , Laszio R. Treiber , Robert Michael Hughes , Onorato Campopiano , Peng Wang , Yuxin Zhao , Helen Chou , Michael Allen Ouellette , Donald Nicholas Hettinger
发明人: Donald J. Gallagher , Laszio R. Treiber , Robert Michael Hughes , Onorato Campopiano , Peng Wang , Yuxin Zhao , Helen Chou , Michael Allen Ouellette , Donald Nicholas Hettinger
IPC分类号: C07D239/54
CPC分类号: C07D239/54 , C07D239/553
摘要: The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.
摘要翻译: 本发明涉及用于制备结构(VI)的促性腺激素释放激素(GnRH)受体拮抗剂的方法和中间体; 及其立体异构体及其药学上可接受的盐。
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公开(公告)号:US20150018553A1
公开(公告)日:2015-01-15
申请号:US14309732
申请日:2014-06-19
发明人: Donald J. Gallagher , Laszlo R. Treiber , Robert Michael Hughes , Onorato Campopiano , Peng Wang , Yuxin Zhao , Shine K. Chou , Michael Allen Ouellette , Donald Nicholas Hettinger
IPC分类号: C07D239/54
CPC分类号: C07D239/54 , C07D239/553
摘要: The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.
摘要翻译: 本发明涉及用于制备结构(VI)的促性腺激素释放激素(GnRH)受体拮抗剂的方法和中间体; 及其立体异构体及其药学上可接受的盐。
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公开(公告)号:US20180346428A1
公开(公告)日:2018-12-06
申请号:US15833513
申请日:2017-12-06
发明人: Donald J. Gallagher , Laszio R. Treiber , Robert Michael Hughes , Onorato Campopiano , Peng Wang , Yuxin Zhao , Shine K. Chou , Michael Allen Ouellette , Donald Nicholas Hettinger
IPC分类号: C07D239/54 , C07D239/553
CPC分类号: C07D239/54 , C07D239/553
摘要: The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.
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公开(公告)号:US09382214B2
公开(公告)日:2016-07-05
申请号:US14309732
申请日:2014-06-19
发明人: Donald J. Gallagher , Laszlo R. Treiber , Robert Michael Hughes , Onorato Campopiano , Peng Wang , Yuxin Zhao , Shine K. Chou , Michael Allen Ouellette , Donald Nicholas Hettinger
IPC分类号: C07D239/02 , C07D239/54 , C07D239/553
CPC分类号: C07D239/54 , C07D239/553
摘要: The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.
摘要翻译: 本发明涉及用于制备结构(VI)的促性腺激素释放激素(GnRH)受体拮抗剂的方法和中间体; 及其立体异构体及其药学上可接受的盐。
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公开(公告)号:US09868706B2
公开(公告)日:2018-01-16
申请号:US15406476
申请日:2017-01-13
发明人: Donald J. Gallagher , Laszlo R. Treiber , Robert Michael Hughes , Onorato Campopiano , Peng Wang , Yuxin Zhao , Shine K. Chou , Michael Allen Ouellette , Donald Nicholas Hettinger
IPC分类号: C07D239/54 , C07D239/553
CPC分类号: C07D239/54 , C07D239/553
摘要: The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.
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公开(公告)号:US20170320836A1
公开(公告)日:2017-11-09
申请号:US15406476
申请日:2017-01-13
发明人: Donald J. Gallagher , Laszlo R. Treiber , Robert Michael Hughes , Onorato Campopiano , Peng Wang , Yuxin Zhao , Shine K. Chou , Michael Allen Ouellette , Donald Nicholas Hettinger
IPC分类号: C07D239/54 , C07D239/553
CPC分类号: C07D239/54 , C07D239/553
摘要: The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.
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