公开(公告)号：US20190328258A1

公开(公告)日：2019-10-31

申请号：US16397618

申请日：2019-04-29

申请人： Duke University

发明人： Stephen Gaeta

IPC分类号： A61B5/04 ,  A61B5/0408

摘要： Systems and methods for quantifying cardiac electrophysiologic signals. An electronic processor receives a unipolar electrogram signal from each of a plurality of electrodes positioned at different locations of a heart. The electronic processor then calculates or measures a bipolar electrogram signal based on a difference between the unipolar electrogram signal for a first electrode and the unipolar electrogram signal for a second electrode. A local activation time (LAT) difference between a location of the first electrode and a local of the second electrode is then determined based on a voltage amplitude of the bipolar electrogram signal. The LAT difference is indicative of an amount of time between a local activation of a propagating wavefront at the location of the first electrode and a local activation of the propagating wavefront at the location of the second electrode.

公开(公告)号：US11382551B2

公开(公告)日：2022-07-12

申请号：US16867065

申请日：2020-05-05

申请人： Duke University

发明人： Stephen Gaeta

IPC分类号： A61B5/333 ,  A61B5/287 ,  A61B5/367

摘要： Systems and methods for recording bipolar electrogram signals by dynamically selecting electrode pairs. For a particular electrode of interest, a reference electrode is identified as the physically closest electrode to the electrode of interest that satisfies at least one selection criterion indicative of an absence of concurrent electrical activation.

公开(公告)号：US11350867B2

公开(公告)日：2022-06-07

申请号：US16397618

申请日：2019-04-29

申请人： Duke University

发明人： Stephen Gaeta

IPC分类号： A61B5/316 ,  A61B5/25 ,  A61B5/341 ,  A61B5/352 ,  A61B5/361

摘要： Systems and methods for quantifying cardiac electrophysiologic signals. An electronic processor receives a unipolar electrogram signal from each of a plurality of electrodes positioned at different locations of a heart. The electronic processor then calculates or measures a bipolar electrogram signal based on a difference between the unipolar electrogram signal for a first electrode and the unipolar electrogram signal for a second electrode. A local activation time (LAT) difference between a location of the first electrode and a local of the second electrode is then determined based on a voltage amplitude of the bipolar electrogram signal. The LAT difference is indicative of an amount of time between a local activation of a propagating wavefront at the location of the first electrode and a local activation of the propagating wavefront at the location of the second electrode.