公开(公告)号：US10245307B2

公开(公告)日：2019-04-02

申请号：US15175644

申请日：2016-06-07

Applicant: Dyax Corp.

Inventor： Robert Charles Ladner ,  Arthur Charles Ley ,  Shirish Hirani ,  Anthony Williams

IPC: A61K38/55 ,  A61P7/00 ,  A61K38/57 ,  A61K9/00 ,  C12N9/64

Abstract: Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.

公开(公告)号：US20140349940A1

公开(公告)日：2014-11-27

申请号：US14263764

申请日：2014-04-28

Applicant: DYAX CORP.

Inventor： Robert C. Ladner ,  Arthur C. Ley ,  Shirish Hirani ,  Anthony Williams

IPC: A61K38/55

CPC classification number: A61K38/57 ,  A61K9/0019 ,  A61K38/55 ,  C12N9/6445

Abstract: Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.

Abstract translation: 描述了用于预防或减少患者中缺血和/或全身炎症反应的方法，例如进行心胸外科手术的患者中的围手术期失血和/或全身炎症反应。 冠状动脉旁路移植术等外科手术，特别是当此类手术涉及体外循环，如体外循环时。

公开(公告)号：US20190247477A1

公开(公告)日：2019-08-15

申请号：US16281276

申请日：2019-02-21

Applicant: Dyax Corp.

Inventor： Robert Charles Ladner ,  Arthur Charles Ley ,  Shirish Hirani ,  Anthony Williams

IPC: A61K38/57 ,  A61K38/55 ,  C12N9/64 ,  A61K9/00

CPC classification number: A61K38/57 ,  A61K9/0019 ,  A61K38/55 ,  C12N9/6445

Abstract: Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.

公开(公告)号：US09480733B2

公开(公告)日：2016-11-01

申请号：US14263764

申请日：2014-04-28

Applicant: DYAX CORP.

Inventor： Robert C. Ladner ,  Arthur C. Ley ,  Shirish Hirani ,  Anthony Williams

IPC: A61K38/55 ,  A61P7/00 ,  A61K38/57 ,  C12N9/64 ,  A61K9/00

CPC classification number: A61K38/57 ,  A61K9/0019 ,  A61K38/55 ,  C12N9/6445

Abstract: Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.

公开(公告)号：US20160361395A1

公开(公告)日：2016-12-15

申请号：US15175644

申请日：2016-06-07

Applicant: Dyax Corp.

Inventor： Robert Charles Ladner ,  Arthur Charles Ley ,  Shirish Hirani ,  Anthony Williams

IPC: A61K38/57 ,  A61K9/00

CPC classification number: A61K38/57 ,  A61K9/0019 ,  A61K38/55 ,  C12N9/6445

Abstract: Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.

Abstract translation: 描述了用于预防或减少患者中缺血和/或全身炎症反应的方法，例如进行心胸外科手术的患者中的围手术期失血和/或全身炎症反应。 冠状动脉旁路移植术等外科手术，特别是当此类手术涉及体外循环，如体外循环时。