公开(公告)号：US20170197907A1

公开(公告)日：2017-07-13

申请号：US15313365

申请日：2015-05-29

申请人： E I DU PONT DE NEMOURS AND COMPANY

发明人： Stephen Ernest Jacobson ,  Donald J. Dumas ,  Rupert Spence ,  Sarah May Crawford ,  Venkateswara Rao Surisetty

IPC分类号： C07C201/12 ,  C07C253/14 ,  C07C231/02

CPC分类号： C07C201/12 ,  C07C231/02 ,  C07C253/14 ,  C07C205/57

摘要： A method for preparing 3-methyl-2-nitrobenzoic acid is disclosed wherein 1,3-dimethyl-2-nitrobenzene is combined with an oxidation catalyst in the presence of an oxygen source and an initiator, provided that less than 99% of the 1,3-dimethyl-2-nitrobenzene is oxidized.A method for preparing compounds of Formula 7 and Formula 11 is also disclosed wherein the method is characterized by using 3-methyl-2-nitrobenzoic acid as prepared by the method disclosed above. wherein R1 is C1-C7 alkyl, C3-C6 cycloalkyl or C4-C7 alkylcycloalkyl

公开(公告)号：US09828328B2

公开(公告)日：2017-11-28

申请号：US15313365

申请日：2015-05-29

申请人： E I DU PONT DE NEMOURS AND COMPANY

发明人： Stephen Ernest Jacobson ,  Donald J. Dumas ,  Rupert Spence ,  Sarah May Crawford ,  Venkateswara Rao Surisetty

IPC分类号： C07C201/12 ,  C07C231/02 ,  C07C253/14

CPC分类号： C07C201/12 ,  C07C231/02 ,  C07C253/14 ,  C07C205/57

摘要： A method for preparing 3-methyl-2-nitrobenzoic acid is disclosed wherein 1,3-dimethyl-2-nitrobenzene is combined with an oxidation catalyst in the presence of an oxygen source and an initiator, provided that less than 99% of the 1,3-dimethyl-2-nitrobenzene is oxidized.A method for preparing compounds of Formula 7 and Formula 11 is also disclosed wherein the method is characterized by using 3-methyl-2-nitrobenzoic acid as prepared by the method disclosed above. wherein R1 is C1-C7 alkyl, C3-C6 cycloalkyl or C4-C7 alkylcycloalkyl.