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公开(公告)号:US10919869B2
公开(公告)日:2021-02-16
申请号:US16302564
申请日:2017-05-17
发明人: Honglin Li , Yufang Xu , Rui Wang , Zhenjiang Zhao , Wenlin Song , Liuxin Xu
IPC分类号: C07D277/50 , A61P19/02 , A61P37/00 , A61P33/00 , A61K31/426 , A61P35/00 , A61P17/06 , A61P31/04
摘要: A thiazole derivative serving as a DHODH inhibitor, and applications thereof. The present invention specifically relates to a compound represented by formula I, a pharmaceutical composition containing the compound represented by formula (I), and applications of the compound in the preparation of drugs for treating diseases mediated by the DHODH or drugs for inhibiting the DHODH.