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公开(公告)号:US20180008561A1
公开(公告)日:2018-01-11
申请号:US15712026
申请日:2017-09-21
IPC分类号: A61K31/155 , A61K9/00 , C07D307/52 , C07D255/02 , C07D251/18 , C07D251/10 , C07D249/14 , A61K45/06 , A61K31/55 , A61K31/53 , A61K31/4196 , A61K31/36 , A61K9/28 , A61K9/20 , C07D317/58 , C07D405/12
CPC分类号: A61K31/155 , A61K9/0053 , A61K9/2054 , A61K9/2813 , A61K9/282 , A61K9/2846 , A61K9/2866 , A61K31/36 , A61K31/4196 , A61K31/53 , A61K31/55 , A61K45/06 , C07D249/14 , C07D251/10 , C07D251/18 , C07D255/02 , C07D307/52 , C07D317/58 , C07D405/12 , A61K2300/00
摘要: Methods for improving the gastrointestinal tolerability of biguanide compounds and for treating metabolic disorders and/or inducing weight loss in patients in need thereof, particularly in individuals having a contraindication for treatment with biguanide compounds, are provided comprising administering delayed release formulations of such biguanide compounds, including metformin, targeted to the small intestine.
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公开(公告)号:US20160095828A1
公开(公告)日:2016-04-07
申请号:US14968696
申请日:2015-12-14
IPC分类号: A61K31/155 , A61K9/28 , A61K45/06 , A61K9/00
CPC分类号: A61K31/155 , A61K9/0053 , A61K9/2054 , A61K9/2813 , A61K9/282 , A61K9/2846 , A61K9/2866 , A61K31/36 , A61K31/4196 , A61K31/53 , A61K31/55 , A61K45/06 , C07D249/14 , C07D251/10 , C07D251/18 , C07D255/02 , C07D307/52 , C07D317/58 , C07D405/12 , A61K2300/00
摘要: Methods for improving the gastrointestinal tolerability of biguanide compounds and for treating metabolic disorders and/or inducing weight loss in patients in need thereof, particularly in individuals having a contraindication for treatment with biguanide compounds, are provided comprising administering delayed release formulations of such biguanide compounds, including metformin, targeted to the small intestine.
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