公开(公告)号：US20170319841A1

公开(公告)日：2017-11-09

申请号：US15150112

申请日：2016-05-09

申请人： Elwha LLC

发明人： JESSE R. CHEATHAM, III ,  JOEL CHERKIS ,  PAUL H. DIETZ ,  TOM DRISCOLL ,  WILLIAM GATES ,  RODERICK A. HYDE ,  MURIEL Y. ISHIKAWA ,  NEIL JORDAN ,  JORDIN T. KARE ,  ERIC C. LEUTHARDT ,  NATHAN P. MYHRVOLD ,  PATRICK NEILL ,  TONY S. PAN ,  ROBERT C. PETROSKI ,  DAVID R. SMITH ,  ELIZABETH A. SWEENEY ,  DESNY S. TAN ,  CLARENCE T. TEGREENE ,  DAVID LAWRENCE TENNENHOUSE ,  YAROSLAV A. URZHUMOV ,  GARY WACHOWICZ ,  LOWELL L. WOOD, JR. ,  VICTORIA Y.H. WOOD

IPC分类号： A61M37/00 ,  A61M35/00

CPC分类号： A61M37/0092 ,  A61M2037/0007

摘要： Described embodiments include a system, method, and apparatus. A system includes a medicament-eluting device configured to be positioned at a location on a skin of a mammal. The system includes an ultrasonic wave transmitter configured to emit ultrasonic shear waves directable at the location. The ultrasonic shear waves have a frequency or amplitude selected to increase a permeability of the skin of the mammal to a medicament released by the medicament-eluting device. In an embodiment, the system includes a structure carrying the medicament-eluting device and the ultrasonic wave transmitter. In an embodiment, the system includes a cavitation sensor configured to detect a cavitation event in the mammal. In an embodiment, the system includes a cavitation controller configured to limit a power of the ultrasonic shear waves directed at the location to a level below a cavitation threshold of the mammal.

公开(公告)号：US20170319840A1

公开(公告)日：2017-11-09

申请号：US15150086

申请日：2016-05-09

申请人： Elwha LLC

发明人： JESSE R. CHEATHAM, III ,  JOEL CHERKIS ,  PAUL H. DIETZ ,  TOM DRISCOLL ,  WILLIAM GATES ,  RODERICK A. HYDE ,  MURIEL Y. ISHIKAWA ,  NEIL JORDAN ,  JORDIN T. KARE ,  ERIC C. LEUTHARDT ,  NATHAN P. MYHRVOLD ,  PATRICK NEILL ,  TONY S. PAN ,  ROBERT C. PETROSKI ,  DAVID R. SMITH ,  ELIZABETH A. SWEENEY ,  DESNY S. TAN ,  CLARENCE T. TEGREENE ,  DAVID LAWRENCE TENNENHOUSE ,  YAROSLAV A. URZHUMOV ,  GARY WACHOWICZ ,  LOWELL L. WOOD, JR. ,  VICTORIA Y.H. WOOD

IPC分类号： A61M37/00 ,  A61F13/15 ,  A61M1/00

CPC分类号： A61M37/0092 ,  A61B2010/008 ,  A61M1/0023 ,  A61M2037/0007 ,  A61M2037/0061 ,  A61M2205/3303 ,  A61M2205/3375

摘要： Described embodiments include a system, method, and apparatus. A system includes an extracellular-fluid collection device configured to be positioned at a location on a skin of a mammal. In an embodiment, the mammal includes a live human. The system includes an ultrasonic wave transmitter configured to emit ultrasonic shear waves directable at the location. The ultrasonic shear waves have a frequency or amplitude selected to increase a permeability of the skin of the mammal to an extracellular-fluid. In an embodiment, the system includes a sensor configured to determine a rate or amount of extracellular-fluid collected by the extracellular-fluid collection device. In an embodiment, the system includes a fluid collection controller configured to regulate a parameter of ultrasonic shear waves transmitted by the ultrasonic wave transmitter in response to a determined rate or amount of fluid collected by the extracellular-fluid collection device.

公开(公告)号：US20170181849A1

公开(公告)日：2017-06-29

申请号：US14982689

申请日：2015-12-29

申请人： ELWHA LLC

发明人： RODERICK A. HYDE ,  ELIZABETH A. SWEENEY ,  LOWELL L. WOOD, JR.

IPC分类号： A61F2/16 ,  G02C7/04 ,  G02C7/08

CPC分类号： A61F2/1627 ,  A61B3/04 ,  A61B3/10 ,  A61F2250/0002 ,  G02C7/04 ,  G02C7/041 ,  G02C7/08 ,  G02C7/083

摘要： Described embodiments include a vision system and a method. A vision system includes a receiver circuit configured to receive data indicative of a presence of a wearable ophthalmic element in an optical path incident on a vision correction device. The vision correction device includes an electronically controllable vision parameter and configured to be placed in an eye of a human subject. The vision system includes a controller circuit coupled to the vision correction device and configured to change the electronically controllable vision parameter of the vision correction device at least partially in response to the received data indicative of the presence of the wearable ophthalmic element in the optical path.

公开(公告)号：US20140303540A1

公开(公告)日：2014-10-09

申请号：US13858738

申请日：2013-04-08

申请人： ELWHA LLC

发明人： MICHAEL H. BAYM ,  RODERICK A. HYDE ,  ELIZABETH A. SWEENEY ,  LOWELL L. WOOD, JR.

IPC分类号： A61F5/01

摘要： Apparatus, system, and method are disclosed herein for controlling movement of an artificial orthopedic joint prosthesis in a mammalian subject. The apparatus, system, or method includes an orthopedic brace configured to control movement of an orthopedic joint prosthesis. The apparatus, system, or method includes one or more sensors and one or more controllers in communication with the one or more sensors. The one or more sensors are configured to detect a change in an orientation of a subject's position in an environment and configured to detect one or more alignment orientations of the orthopedic joint prosthesis.

摘要翻译： 本文公开了用于控制哺乳动物受试者中的人造整形外科关节假体的移动的装置，系统和方法。 该装置，系统或方法包括构造成控制整形外科关节假体运动的矫形支架。 装置，系统或方法包括与一个或多个传感器通信的一个或多个传感器和一个或多个控制器。 一个或多个传感器被配置为检测对象在环境中的位置的取向的变化并且被配置为检测整形外科关节假体的一个或多个对准取向。