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公开(公告)号：US09046292B2
公开(公告)日：2015-06-02
申请号：US13654595
申请日：2012-10-18
Applicant: EMD Millipore Corporation
Inventor： Aaron Burke , Michael Felo , Brian Pereira , Elias Noukas , Dennis Wong
CPC classification number: F25D29/00 , A01N1/0263 , F25D2331/802 , F25D2400/28 , F25D2400/30 , F25D2600/06 , F25D2700/12 , Y10T29/53
Abstract: The biocontainer of the present invention provides a low cost, simple solution of many of the problems encountered during shipping, freezing and thawing of biopharmaceutical materials. The present invention enables a user to monitor the temperature profile of each biopharmaceutical container during the cryogenic process, so as to ensure the integrity of materials within each biocontainer by using a pre-installed and pre-sterilized temperature sensor. In some embodiments, the sensor assembly includes a wireless transmitter and is capable of transmitting information regarding the measured reading. In other embodiments, the sensor assembly includes a processing unit, which determines whether the temperature profile is acceptable. In a further embodiment, an indicator is included, such that the processing unit may indicate whether the biopharmaceutical material has been properly frozen. In other embodiments, the sensor assembly also includes a storage element, which is capable of storing various parameters during the freezing process.
Abstract translation: 本发明的生物容器提供了在生物药物材料的运输，冷冻和解冻期间遇到的许多问题的低成本，简单的解决方案。 本发明使得用户能够在低温过程期间监测每个生物药物容器的温度曲线，以便通过使用预先安装和预灭菌的温度传感器来确保每个生物容器内的材料的完整性。 在一些实施例中，传感器组件包括无线发射器，并且能够发送关于测量读数的信息。 在其他实施例中，传感器组件包括处理单元，其确定温度分布是否可接受。 在另一实施例中，包括指示器，使得处理单元可以指示生物药物材料是否已被适当地冷冻。 在其他实施例中，传感器组件还包括存储元件，其能够在冷冻过程期间存储各种参数。
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公开(公告)号：US09027356B2
公开(公告)日：2015-05-12
申请号：US13654593
申请日：2012-10-18
Applicant: EMD Millipore Corporation
Inventor： Aaron Burke , Michael Felo , Brian Pereira , Elias Noukas , Dennis Wong
CPC classification number: F25D29/00 , A01N1/0263 , F25D2331/802 , F25D2400/28 , F25D2400/30 , F25D2600/06 , F25D2700/12 , Y10T29/53
Abstract: The biocontainer of the present invention provides a low cost, simple solution of many of the problems encountered during shipping, freezing and thawing of biopharmaceutical materials. The present invention enables a user to monitor the temperature profile of each biopharmaceutical container during the cryogenic process, so as to ensure the integrity of materials within each biocontainer by using a pre-installed and pre-sterilized temperature sensor. In some embodiments, the sensor assembly includes a wireless transmitter and is capable of transmitting information regarding the measured reading. In other embodiments, the sensor assembly includes a processing unit, which determines whether the temperature profile is acceptable. In a further embodiment, an indicator is included, such that the processing unit may indicate whether the biopharmaceutical material has been properly frozen. In other embodiments, the sensor assembly also includes a storage element, which is capable of storing various parameters during the freezing process.
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公开(公告)号：US20130039382A1
公开(公告)日：2013-02-14
申请号：US13654595
申请日：2012-10-18
Applicant: EMD Millipore Corporation
Inventor： Aaron Burke , Michael Felo , Brian Pereira , Elias Noukas , Dennis Wong
IPC: G01N25/00
CPC classification number: F25D29/00 , A01N1/0263 , F25D2331/802 , F25D2400/28 , F25D2400/30 , F25D2600/06 , F25D2700/12 , Y10T29/53
Abstract: The biocontainer of the present invention provides a low cost, simple solution of many of the problems encountered during shipping, freezing and thawing of biopharmaceutical materials. The present invention enables a user to monitor the temperature profile of each biopharmaceutical container during the cryogenic process, so as to ensure the integrity of materials within each biocontainer by using a pre-installed and pre-sterilized temperature sensor. In some embodiments, the sensor assembly includes a wireless transmitter and is capable of transmitting information regarding the measured reading. In other embodiments, the sensor assembly includes a processing unit, which determines whether the temperature profile is acceptable. In a further embodiment, an indicator is included, such that the processing unit may indicate whether the biopharmaceutical material has been properly frozen. In other embodiments, the sensor assembly also includes a storage element, which is capable of storing various parameters during the freezing process.
Abstract translation: 本发明的生物容器提供了在生物药物材料的运输，冷冻和解冻期间遇到的许多问题的低成本，简单的解决方案。 本发明使得用户能够在低温过程期间监测每个生物药物容器的温度曲线，以便通过使用预先安装和预灭菌的温度传感器来确保每个生物容器内的材料的完整性。 在一些实施例中，传感器组件包括无线发射器，并且能够发送关于测量读数的信息。 在其他实施例中，传感器组件包括处理单元，其确定温度分布是否可接受。 在另一实施例中，包括指示器，使得处理单元可以指示生物药物材料是否已被适当地冷冻。 在其他实施例中，传感器组件还包括存储元件，其能够在冷冻过程期间存储各种参数。
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公开(公告)号：US20130038469A1
公开(公告)日：2013-02-14
申请号：US13654593
申请日：2012-10-18
Applicant: EMD Millipore Corporation
Inventor： Aaron Burke , Michael Felo , Brian Pereira , Elias Noukas , Dennis Wong
IPC: G08C19/00
CPC classification number: F25D29/00 , A01N1/0263 , F25D2331/802 , F25D2400/28 , F25D2400/30 , F25D2600/06 , F25D2700/12 , Y10T29/53
Abstract: The biocontainer of the present invention provides a low cost, simple solution of many of the problems encountered during shipping, freezing and thawing of biopharmaceutical materials. The present invention enables a user to monitor the temperature profile of each biopharmaceutical container during the cryogenic process, so as to ensure the integrity of materials within each biocontainer by using a pre-installed and pre-sterilized temperature sensor. In some embodiments, the sensor assembly includes a wireless transmitter and is capable of transmitting information regarding the measured reading. In other embodiments, the sensor assembly includes a processing unit, which determines whether the temperature profile is acceptable. In a further embodiment, an indicator is included, such that the processing unit may indicate whether the biopharmaceutical material has been properly frozen. In other embodiments, the sensor assembly also includes a storage element, which is capable of storing various parameters during the freezing process.
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