公开(公告)号：US11993563B2

公开(公告)日：2024-05-28

申请号：US17286949

申请日：2019-10-31

申请人： ENANTIA S.L.

发明人： Nicolas Tesson ,  Montserrat Trilla Castaño ,  Alexander Christian Comely

IPC分类号： C07C37/84 ,  A61K31/05 ,  A61K31/352 ,  C07C37/88 ,  C07C39/19 ,  C07C39/23 ,  C07C229/12 ,  C07C229/22 ,  C07D311/80 ,  A61K9/20 ,  A61K9/48

CPC分类号： C07C37/84 ,  A61K31/05 ,  A61K31/352 ,  C07C37/88 ,  C07C39/19 ,  C07C39/23 ,  C07C229/12 ,  C07C229/22 ,  C07D311/80 ,  A61K9/2013 ,  A61K9/2095 ,  A61K9/4808 ,  A61K9/4858 ,  C07B2200/13 ,  C07C2601/16 ,  C07C37/84 ,  C07C39/19 ,  C07C37/84 ,  C07C39/23

摘要： The present invention relates to solid compositions comprising cocrystals of cannabinoids, processes for their preparation, and their use as in therapy or in cosmetics or for the purification of cannabinoids. It also relates to cocrystals of cannabinoids.

公开(公告)号：US11168047B2

公开(公告)日：2021-11-09

申请号：US16636888

申请日：2018-08-06

申请人： ENANTIA, S.L.

发明人： Alexander Christian Comely ,  Nicolas Tesson ,  Carmen Jiménez González

IPC分类号： C07C39/17 ,  C07C37/84 ,  C07C229/12 ,  C07C229/22 ,  C07D209/42

摘要： The present invention relates to cocrystals of 2-[(1R,6R)-6-isopropenyl-3-methylcyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol and a zwitterion coformer, processes for their preparation, and their use as a medicament and for the purification of 2-[(1R,6R)-6-isopropenyl-3-methylcyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol. The invention also relates to compositions comprising the cocrystal.

公开(公告)号：US20150087686A1

公开(公告)日：2015-03-26

申请号：US14396370

申请日：2013-04-24

申请人： ENANTIA, S.L.

发明人： Nicolas Tesson ,  Montserrat Trilla Castaño ,  Lydia Cárdenas Romaña ,  Llorenç Rafecas Jané

IPC分类号： C07D209/52

CPC分类号： C07D209/52

摘要： It comprises a cocrystal of saxagliptin hydrochloride and a compound selected from the group consisting of saxagliptin, glycolic acid, malonic acid, and urea; or a solvate thereof, or a hydrate thereof. It also comprises a salt of saxagliptin with glycolic acid 1:1 hydrate. It also comprises their preparation processes, as well as their use as antidiabetics.

摘要翻译： 它包括盐酸沙格列汀的共结晶体和选自沙格列汀，乙醇酸，丙二酸和尿素的化合物; 或其溶剂合物，或其水合物。 它还包含沙格列汀与乙醇酸1：1水合物的盐。 它还包括其制备过程，以及它们作为抗糖尿病药物的用途。