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公开(公告)号：US20240351966A1
公开(公告)日：2024-10-24
申请号：US18290268
申请日：2022-05-11
发明人： Fajun NAN , Jingya LI , Zheng ZHANG , Yanan DUAN , Yangming ZHANG , Dandan CHEN , Chengqiu DAI
IPC分类号： C07C39/19 , A61K31/05 , A61K31/09 , A61K31/136 , A61K31/145 , A61K31/167 , A61K31/341 , A61K31/381 , A61K31/40 , A61K31/44 , A61K31/505 , C07C43/215 , C07C43/23 , C07C215/76 , C07C233/88 , C07D213/69 , C07D213/74 , C07D239/10 , C07D307/36 , C07D333/06 , C07D333/34
CPC分类号： C07C39/19 , A61K31/05 , A61K31/09 , A61K31/136 , A61K31/145 , A61K31/167 , A61K31/341 , A61K31/381 , A61K31/40 , A61K31/44 , A61K31/505 , C07C43/215 , C07C43/23 , C07C215/76 , C07C233/88 , C07D213/69 , C07D213/74 , C07D239/10 , C07D307/36 , C07D333/06 , C07D333/34
摘要： Provided are a class of alkylphenol compounds and a preparation method therefor. Specifically provided are a new alkyl polyphenol compound as represented by chemical formula I, and a preparation method therefor and the use thereof in the treatment of metabolic syndrome.
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公开(公告)号：US20230332008A1
公开(公告)日：2023-10-19
申请号：US18029934
申请日：2021-10-14
发明人： Koji HASEGAWA , Shiori NONAKA , Osamu WATANABE
IPC分类号： C09D11/52 , C09D11/037 , C09D11/102 , C07C43/23 , C07C39/16 , C07C39/19 , C07C69/50 , C07F7/08 , H01B1/22 , H01B5/14 , H01B13/00
CPC分类号： C09D11/52 , C09D11/037 , C09D11/102 , C07C43/23 , C07C39/16 , C07C39/19 , C07C69/50 , C07F7/081 , C07F7/0838 , H01B1/22 , H01B5/14 , H01B13/0016
摘要： The present invention is a phenol compound represented by the following general formula (1A). This phenol compound makes it possible to provide a phenol compound as an additive for a conductive paste composition having a small decrease in electric conductivity in repetitive elongations and shrinkages and excellent printing processability, a conductive paste composition containing the additive, and a conductive wire made by using the conductive paste composition.
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3.发明公开公开(公告)号：US20230278942A1
公开(公告)日：2023-09-07
申请号：US18053589
申请日：2022-11-08
申请人： DREXEL UNIVERSITY , The Government of the United States of America, as represented by The Secretary of the Army
IPC分类号： C07C39/19 , C08F222/20
CPC分类号： C07C39/19 , C08F222/20
摘要： A polymerizable monomer prepared by reacting at least one epoxidized cardanol with (meth)acrylic anhydride or (meth)acryloyl chloride in the presence of one or more of triethylamine, tertiary amines, pyridines and pyridine derivatives; wherein the epoxidized cardanol is formed by epoxidation of an unsaturation site of a cardanol having the formula:
wherein R is selected from hydrogen and an alkyl, or alkenyl group having 1-6 carbon atoms, and n is 7, 10, or 13, a polymer and resin made form the polymerizable monomer, and a method of preparing such a polymer. The resin created from this monomer is suitable for moderate temperature composites and coatings applications.-
公开(公告)号：US11732141B2
公开(公告)日：2023-08-22
申请号：US16277473
申请日：2019-02-15
IPC分类号： C08F12/22 , C09D4/00 , C08F293/00 , C07C69/54 , C08F12/24 , C07C49/794 , C07C39/20 , C07C63/04 , C07C39/19 , C07C63/64 , C07C69/017 , C07C47/548
CPC分类号： C09D4/00 , C07C69/54 , C08F293/005 , C07C39/19 , C07C39/20 , C07C47/548 , C07C49/794 , C07C63/04 , C07C63/64 , C07C69/017 , C08F12/22 , C08F12/24 , C08F2438/03 , C09D4/00 , C08F220/282
摘要： Dimethoxyphenol-based monomers containing polymerizable functional groups such as [meth]acrylate groups are useful for the preparation of polymers, wherein one or more dimethoxyphenyl moieties are part of side chains pendant to the backbones of the polymers. The polymers thereby obtained may have different, improved properties, such as higher glass transition temperatures, thermal stability and solvent resistance, as compared to polymers based on other types of lignin-derived monomers.
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公开(公告)号：US20210276936A1
公开(公告)日：2021-09-09
申请号：US17324419
申请日：2021-05-19
发明人： Thomas Smeltzer , Robert Davis , Sean Colvin , Jacob Black
IPC分类号： C07C39/19 , C07C37/11 , C07C37/68 , C07C43/285 , B01J27/128 , B01J31/02 , B01J27/232 , B01J27/08 , B01J27/138 , C07F7/08
摘要： Multiple methods of synthesizing cannabigerol are presented. Combining olivetol with geraniol derivatives are provided. Cross-coupling methods of combing functionalized resorcinols are provided. Useful intermediates are formed during such cross-coupling steps.
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公开(公告)号：US11021424B2
公开(公告)日：2021-06-01
申请号：US12777179
申请日：2010-05-10
申请人： Guy M. Miller , Sidney M. Hecht
发明人： Guy M. Miller , Sidney M. Hecht
IPC分类号： C07C37/07 , A61K31/355 , C07C39/08 , C07C39/19 , C07C39/24 , C07C46/00 , C07C46/02 , C07C46/08 , C07C50/02 , C07C50/06 , C07C50/28 , A61P25/00
摘要： Methods of treating or suppressing mitochondrial diseases, such as Friedreich's ataxia (FRDA), Leber's Hereditary Optic Neuropathy (LHON), mitochondrial myopathy, encephalopathy, lactacidosis, stroke (MELAS), or Kearns-Sayre Syndrome (KSS) are disclosed, as well as compounds useful in the methods of the invention, such as alpha-tocopherol quinone. Methods and compounds useful in treating other disorders are also disclosed. Energy biomarkers useful in assessing the metabolic state of a subject and the efficacy of treatment are also disclosed. Methods of modulating, normalizing, or enhancing energy biomarkers, as well as compounds useful for such methods, are also disclosed.
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公开(公告)号：US20190062272A1
公开(公告)日：2019-02-28
申请号：US16093294
申请日：2017-04-12
发明人： Dinesh CHIMMANAMADA , Weiwen YING
IPC分类号： C07C323/25 , A61P35/00 , C07C323/41 , C07C39/08 , C07C39/19 , C07C50/02
摘要： The present invention relates to new compounds for immunogenic treatment of cancer. The compounds can be administered as a single agent or in combination with an anticancer drug including modulators of other immune pathways, especially immune checkpoint inhibitors that target CTLA-4, PD-1, and PD-L1 proteins. The compounds can produce neoantigens through irreversible protein binding in cancer cells and generate immune response.
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8.发明申请公开(公告)号：US20180237399A1
公开(公告)日：2018-08-23
申请号：US15772105
申请日：2016-11-01
发明人： Fajun NAN , Xin XIE , Yang LIU , Qing ZHANG , Linhai CHEN , Hui YANG
IPC分类号： C07D239/60 , C07D239/52 , C07D213/69 , C07C49/825 , C07C39/19
CPC分类号： C07D239/60 , A61K31/505 , C07C39/08 , C07C39/19 , C07C49/825 , C07D213/69 , C07D239/48 , C07D239/52 , C07D239/54 , C07D239/545 , C07D239/56 , C07D251/20 , C07D309/38
摘要： The present invention relates to a class of compounds represented by the formula I, or pharmaceutically acceptable salts thereof, methods for their preparation, and application as small molecule tools that function as GPR84 agonists, and their use in preparing a medicament for the treatment of septicemia.
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公开(公告)号：US20180035669A1
公开(公告)日：2018-02-08
申请号：US15546910
申请日：2016-01-25
发明人： Katy Paulina DIAZ PERALTA , Luis Javier ESPINOZA CATALAN , Floreal Andres OLEA CARRASCO , Hugo Alberto PEÑA CORTES , Lautaro Liber TABORGA MORALES
摘要： The present invention discloses a synthesis process for obtaining linear derivative compounds from geranylorcinoles, said linear derivative compounds from geraniylorcinol, the acetylated derivatives compounds therefrom, the method for encapsulating the compounds in a polymer matrix and the use of said encapsulated compounds as antifungal against Botrytis Cinerea.
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公开(公告)号：US09469836B2
公开(公告)日：2016-10-18
申请号：US13360240
申请日：2012-01-27
IPC分类号： A01N49/00 , C12N1/14 , C07D309/06 , C07D321/00 , C12P7/22 , C12P7/40 , C12P17/08 , C12R1/645 , C07C39/19 , A01N43/16 , A01N37/42 , A01N43/24
CPC分类号： C12N1/14 , A01N37/42 , A01N43/16 , A01N43/24 , A01N49/00 , C07C39/19 , C07D309/06 , C07D321/00 , C12P7/22 , C12P7/40 , C12P17/08 , C12R1/645
摘要： The disclosure pertains to isolated white pine toxigenic endophytes and the compounds produced by the fungal endophytes as well as methods and uses of the white pine endophytes. The isolated white pine toxigenic endophytes are useful for preparing white pine seedlings and plants that have increased tolerance to a pest and are prepared by inoculating a white pine seedling during the susceptible time window.
摘要翻译： 本公开涉及分离的白松产生内生真菌和由真菌内生菌产生的化合物以及白松内生菌的方法和用途。 分离的白松产生内生真菌可用于制备具有增加的对害虫耐受性的白松幼苗和植物，并且通过在易感时间窗口期间接种白松幼苗来制备。
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