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公开(公告)号：US20240293520A1
公开(公告)日：2024-09-05
申请号：US18654304
申请日：2024-05-03
申请人： ENTEROME S.A.
CPC分类号： A61K39/001119 , A61K39/00115 , A61K39/001152 , A61K39/001154 , A61P35/00 , A61K2039/55566
摘要： The present invention relates to antigen-based immunotherapy, in particular cancer immunotherapy. In particular, the present invention provides antigenic peptides, which are distinct from, but have amino acid similarity to, fragments of human tumor antigens. The present invention further provides immunogenic compounds, nanoparticles, cells and pharmaceutical compositions comprising such antigenic peptides and nucleic acids encoding such antigenic peptides.
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公开(公告)号：US20240342261A1
公开(公告)日：2024-10-17
申请号：US18751502
申请日：2024-06-24
申请人： ENTEROME S.A.
发明人： Laurent CHENE , Alban MATHIEU , Matthieu PICHAUD
CPC分类号： A61K39/0011 , A61K39/00114 , A61K39/39 , A61P35/00 , A61K2039/5158 , A61K2039/53 , A61K2039/55555 , A61K2039/572 , A61K2039/6031
摘要： The invention relates to an immunogenic compound comprising an antigenic peptide having amino acid similarity with a tumor antigen, which antigenic peptide is selected in the group consisting of peptides having amino acid similarity with IL13RA2, the said antigenic peptide being selected in the group consisting of sequences described in the specification.
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3.发明公开公开(公告)号：US20230221331A1
公开(公告)日：2023-07-13
申请号：US17794085
申请日：2021-01-22
申请人： ENTEROME S.A.
IPC分类号： G01N33/68 , C12N15/10 , G01N33/569 , A61P37/02 , A61K38/16
CPC分类号： G01N33/6842 , A61K38/164 , A61P37/02 , C12N15/1055 , G01N33/56911
摘要： The present invention relates to the treatment of diseases relating to proteins of the human microbiome metasecretome and, thus, to microbiome interactions, especially microbiome-host interactions. In particular the present invention relates to a method for identification of secreted peptides and proteins of the human microbiome. The present invention also relates to methods for generating a database of human microbiome metasecretome protein sequences. Furthermore, the present invention relates to a method for preparing a protein of the human microbiome metasecretome as well as to the use of such proteins in medicine.
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公开(公告)号：US20240075117A1
公开(公告)日：2024-03-07
申请号：US18341337
申请日：2023-06-26
申请人： ENTEROME S.A.
IPC分类号： A61K39/00 , A61P35/00 , G01N33/574 , G01N33/68 , G16B30/00
CPC分类号： A61K39/0011 , A61P35/00 , G01N33/574 , G01N33/6878 , G16B30/00 , A61K39/0208
摘要： The present invention relates to cancer immunotherapy, in particular to sequence variants of tumor-related antigenic epitope sequences. Namely, the present invention provides a method for identification of microbiota sequence variants of tumor-related antigenic epitope sequences. Such microbiota sequence variants are useful for the preparation of anticancer medicaments, since they differ from self-antigens and, thus, they may elicit a strong immune response. Accordingly, medicaments comprising microbiota sequence variants, methods of preparing such medicaments and uses of such medicaments are provided.
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公开(公告)号：US20200256877A1
公开(公告)日：2020-08-13
申请号：US16753657
申请日：2018-10-09
申请人： ENTEROME S.A.
IPC分类号： G01N33/68 , G01N33/574 , G16B30/10 , G16B45/00 , G01N33/569 , A61K39/00 , A61K39/39 , A61K9/51
摘要： The present invention relates to cancer immunotherapy, in particular to sequence variants of tumor-related antigenic epitope sequences. Namely, the present invention provides a method for identification of microbiota sequence variants of tumor-related antigenic epitope sequences. Such microbiota sequence variants are useful for the preparation of anticancer medicaments, since they differ from self-antigens and, thus, they may elicit a strong immune response. Accordingly, medicaments comprising microbiota sequence variants, methods of preparing such medicaments and uses of such medicaments are provided.
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公开(公告)号：US20240033335A1
公开(公告)日：2024-02-01
申请号：US18354966
申请日：2023-07-19
申请人： ENTEROME S.A.
CPC分类号： A61K39/001112 , A61P35/00 , A61K39/001124 , A61K39/001129 , A61K39/001113 , A61K39/001117 , A61K2039/55516 , A61K2039/55566
摘要： The present invention relates to antigen-based immunotherapy, in particular cancer immunotherapy. In particular, the present invention provides antigenic peptides, which are distinct from, but have amino acid similarity to, especially share the same core sequence with epitopes of human tumor antigens. The present invention further provides immunogenic compounds, nanoparticles, cells and pharmaceutical compositions comprising such antigenic peptides and nucleic acids encoding such antigenic peptides.
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公开(公告)号：US20230080443A1
公开(公告)日：2023-03-16
申请号：US17929063
申请日：2022-09-01
申请人： ENTEROME S.A.
发明人： Laurent CHENE , Alban Mathieu , Matthiew Pichaud
摘要： The invention relates to an immunogenic compound comprising an antigenic peptide having amino acid similarity with a tumor antigen, which antigenic peptide is selected in the group consisting of peptides having amino acid similarity with IL13RA2, the said antigenic peptide being selected in the group consisting of sequences described in the specification.
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公开(公告)号：US20210113678A1
公开(公告)日：2021-04-22
申请号：US17043192
申请日：2019-04-11
申请人： ENTEROME S.A.
摘要： The present invention relates to antigen-based immunotherapy, in particular cancer immunotherapy. In particular, the present invention provides antigenic peptides, which are distinct from, but have amino acid similarity to, fragments of human tumor antigens. The present invention further provides immunogenic compounds, nanoparticles, cells and pharmaceutical compositions comprising such antigenic peptides and nucleic acids encoding such antigenic peptides.
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公开(公告)号：US20200025774A1
公开(公告)日：2020-01-23
申请号：US16338954
申请日：2017-10-09
申请人： ENTEROME S.A.
IPC分类号： G01N33/68 , G01N33/574 , A61K39/00
摘要： The present invention relates to cancer immunotherapy, in particular to sequence variants of tumor-related antigenic epitope sequences. Namely, the present invention provides a method for identification of microbiota sequence variants of tumor-related antigenic epitope sequences. Such microbiota sequence variants are useful for the preparation of anticancer medicaments, since they differ from self-antigens and, thus, they may elicit a strong immune response. Accordingly, medicaments comprising microbiota sequence variants, methods of preparing such medicaments and uses of such medicaments are provided.
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公开(公告)号：US20190388532A1
公开(公告)日：2019-12-26
申请号：US16338955
申请日：2017-10-09
申请人： ENTEROME S.A.
发明人： Laurent CHENE , Alban MATHIEU , Matthieu PICHAUD
摘要： The invention relates to an immunogenic compound comprising an antigenic peptide having amino acid similarity with a tumor antigen, which antigenic peptide is selected in the group consisting of peptides having amino acid similarity with IL13RA2, the said antigenic peptide being selected in the group consisting of sequences described in the specification.
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