专利检索 ap:("ENZYCHEM LIFESCIENCES CORPORATION" OR "KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY") AND inv:"Young Sik Jung" 第 1 页

1.

发明授权
Compositions containing monoacetyldiacylglycerol compound as an active ingredient for preventing or treating rheumatoid arthritis 有权

公开(公告)号：US09895337B2

公开(公告)日：2018-02-20

申请号：US15048732

申请日：2016-02-19

申请人： ENZYCHEM LIFESCIENCES CORPORATION , KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY

发明人： Jae Wha Kim , Sei Ryang Oh , Kyung Seop Ahn , Ho Bum Kang , Beom Su Park , Tae Suk Lee , Jong Koo Kang , Young Sik Jung , Ki-Young Sohn

IPC分类号： A61K31/231 , A61K9/00 , A61K9/48 , A61K31/23

CPC分类号： A61K31/231 , A61K9/0053 , A61K9/4825 , A61K31/23

摘要： The invention relates to pharmaceutical compositions, as well as health functional food compositions and quasi-drug compositions, for preventing, treating, or improving rheumatoid arthritis, comprising a monoacetyldiacylglycerol compound as an active ingredient. The monoacetyldiacylglycerol of the invention is effective in inhibiting the phosphorylation of STAT-3 known to be a therapeutic target for rheumatoid arthritis. As the monoacetyldiacylglycerol is an effective therapeutic agent without toxicity, the monoacetyldiacylglycerol can overcome the side effects of the medicines currently used in the treatment of rheumatoid arthritis. Thus, the monoacetyldiacylglycerol can be used for preventing, treating or improving rheumatoid arthritis.