公开(公告)号：US20230235297A1

公开(公告)日：2023-07-27

申请号：US18008939

申请日：2021-06-08

Applicant: ERBER AKTIENGESELLSCHAFT

Inventor： Bernhard Neumayer ,  Elisabeth Streit ,  Barbara Weber ,  Gudrun Vogtentanz

IPC: C12N9/02 ,  A23K20/189 ,  A23L29/00

CPC classification number: C12N9/0008 ,  A23K20/189 ,  A23L29/06 ,  C12Y197/00

Abstract: The present invention relates to a method of converting 3-keto-DON into 3-epi-DON, reducing the content of DON in a composition comprising DON or of reducing the toxicity of a composition comprising DON as well as a method for converting a trichothecene comprising a 3-oxo group into a trichothecene comprising a 3-hydroxy group using one or more polypeptide(s) comprising or consisting of SEQ ID NO. 1 or a sequence having a sequence identity of at least 72.0% to SEQ ID NO. 1. Also envisioned are feed or food additives or feed or food as well as pharmaceutical compositions comprising one or more polypeptide(s) comprising or consisting of a sequence of SEQ ID NO. 1 or a sequence having a sequence identity of at least 72.0% to SEQ ID NO. 1 as well as the manufacture thereof. Encompassed are further polypeptide(s) comprising or consisting of a sequence of SEQ ID NO. 1 or a sequence having a sequence identity of at least 88.5% to SEQ ID NO. 1. Also envisioned are host cells or plants.

公开(公告)号：US20220372450A1

公开(公告)日：2022-11-24

申请号：US17638756

申请日：2020-08-28

Applicant: ERBER AKTIENGESELLSCHAFT

Inventor： Bernhard Neumayer ,  Elisabeth Streit ,  Barbara Weber ,  Gudrun Vogtentanz

IPC: C12N9/02 ,  A61K47/02

Abstract: The present invention relates to compositions comprising one or more polypeptide(s) comprising or consisting of a sequence of SEQ ID NO. 1-14 or a sequence having a sequence identity of at least 75% to any one of SEQ ID NO. 1-14 and a carrier as well as uses and methods of these polypeptides.