-
公开(公告)号：US12031991B2
公开(公告)日：2024-07-09
申请号：US16977003
申请日：2019-02-28
发明人： Monika Flügel , Stefan Pelzer , Frank Thiemann , Filip Van Immerseel , Richard Ducatelle , Evy Goossens , Bart Devreese , Griet Debyser
IPC分类号： G01N33/68 , G01N33/543
CPC分类号： G01N33/6893 , G01N33/543 , G01N33/54306 , G01N33/54388 , G01N2333/79 , G01N2800/06
摘要： The present invention pertains to an in vitro method for detecting intestinal barrier failure in an avian population, the method comprising the following steps: a) collecting a pooled fecal sample deriving from an avian population and b) determining the amount of at least one protein marker contained in said sample; wherein the at least one protein marker comprises or consists of an acute phase protein or a functional fragment thereof, and wherein an increased amount of said at least one protein marker contained in said sample versus a reference sample indicates intestinal barrier failure.
-
公开(公告)号：US11643696B2
公开(公告)日：2023-05-09
申请号：US16612398
申请日：2018-05-09
发明人： Monika Flügel , Stefan Pelzer , Filip Van Immerseel , Richard Ducatelle , Evy Goossens , Sarah Hark , Frank Thiemann , Florian Böhl
摘要： The present invention relates to a method for detecting C. perfringens induced diseases in animals, the method comprising: a) collecting sample material of a specific animal or of a specific group of animals at consecutive points in time; b) determining the amount of a first marker and a second marker contained in the sample material; and c) determining the ratio of the first marker to the second marker contained in the sample material; wherein the first marker comprises a polynucleotide sequence being specific for the C. perfringens sub-species inducing the targeted disease; and the second marker comprises a polynucleotide being specific for the species C. perfringens; and wherein an increase in the ratio of the first marker to the second marker in the analyzed sample material over time is an indication of the targeted disease.
-
搜索结果
2 条记录 (耗时 0.011 秒)
