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公开(公告)号：US20180237814A1
公开(公告)日：2018-08-23
申请号：US15952377
申请日：2018-04-13
发明人： Steffen Osswald , Heiko Schuster , Jurgen Roos , Andreas Karau , Ulrich Schwaneberg , Ronny Martinez , Hemanshu Mundhada , Ursula Holter
摘要： The present invention relates to it hydantoinase having an amino acid sequence selected from (i) or (ii), with (i) amino acid sequence selected from SEQ ID NO: 6-20 and SEQ ID NO: 73-119 (ii) amino acid sequence wherein in the amino acid sequence of SEQ ID NO: 6-20 and SEQ ID NO: 73-119, 1 to 75 amino acid residues have been substituted, deleted, inserted and/or added, and wherein further the catalytic activity of the hydantoinase is higher by a factor of at least 1.2 than the catalytic activity of the hydantoinase having amino acid sequence SEQ ID NO: 1. The present invention further relates to a process for preparing amino acids, wherein said hydantoinase is used.
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公开(公告)号：US10822627B2
公开(公告)日：2020-11-03
申请号：US15952377
申请日：2018-04-13
发明人： Steffen Osswald , Heiko Schuster , Jurgen Roos , Andreas Karau , Ulrich Schwaneberg , Ronny Martinez , Hemanshu Mundhada , Ursula Holter
摘要： The present invention relates to a hydantoinase having an amino acid sequence selected from (i) or (ii), with (i) amino acid sequence selected from SEQ ID NO: 6-20 and SEQ ID NO: 73-119 (ii) amino acid sequence wherein in the amino acid sequence of SEQ ID NO: 6-20 and SEQ ID NO: 73-119, 1 to 75 amino acid residues have been substituted, deleted, inserted and/or added, and wherein further the catalytic activity of the hydantoinase is higher by a factor of at least 1.2 than the catalytic activity of the hydantoinase having amino acid sequence SEQ ID NO: 1. The present invention further relates to a process for preparing amino acids, wherein said hydantoinase is used.
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