公开(公告)号：US20210087152A1

公开(公告)日：2021-03-25

申请号：US16764698

申请日：2018-10-10

Applicant: East China University of Science and Technology

Inventor： Zhong LI ,  Guobin REN ,  Xiaoyorig XU ,  Minghui QI ,  Jian HU ,  Chengyu GONG

IPC: C07D249/08 ,  A01N43/653

Abstract: A tebuconazole polymorph and a preparation method therefor are described. In particular, a polymorph of (RS)-1-(4-chloropheny)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl) pentan-3-ol, a preparation method therefor and use thereof are provided. The tebuconazole polymorph has a high purity and excellent crystallization properties, is stable under high humidity, high temperature and light conditions, has excellent solubility, and has high processing properties for formulations, high biological activities and good sterilization effects. The preparation method is simple, has stable processes, and can be implemented on a large scale. The polymorph can greatly improve the quality control and industrial application of tebuconazole-containing pesticides.