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公开(公告)号：US20150182496A1
公开(公告)日：2015-07-02
申请号：US14595746
申请日：2015-01-13
Applicant: Eisai R&D Management Co., Ltd.
Inventor： Sergei Agoulnik , Bruce Decosta , Hong Du , Yimin Jiang , Xiang-Yi Li , Kenichi Nomoto , John (Yuan) Wang , Huiming Zhang
IPC: A61K31/365 , A61K31/496 , A61K45/06 , A61K31/4025 , A61K31/422 , A61K31/665 , A61K31/4178 , A61K31/5377
CPC classification number: A61K31/365 , A61K31/4025 , A61K31/4178 , A61K31/422 , A61K31/4523 , A61K31/496 , A61K31/5377 , A61K31/665 , A61K45/06
Abstract: The present invention provides compounds, pharmaceutical compositions and methods for the treatment of specific cancers. Such compositions may generally comprise a compound of formula (I): wherein R1-R3 are as defined herein, or pharmaceutically acceptable salts or esters thereof; and a pharmaceutically acceptable carrier.
Abstract translation: 本发明提供了用于治疗特定癌症的化合物，药物组合物和方法。 这样的组合物通常可以包含式（I）的化合物：其中R 1 -R 3如本文所定义，或其药学上可接受的盐或酯; 和药学上可接受的载体。
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公开(公告)号：US20180353468A1
公开(公告)日：2018-12-13
申请号：US15960259
申请日：2018-04-23
Applicant: Eisai R&D Management Co., LTD.
Inventor： Sergei Agoulnik , Bruce Decosta , Hong Du , Yimin Jiang , Xiang-Yi Li , Kenichi Nomoto , John (Yuan) Wang , Huiming Zhang
IPC: A61K31/365 , A61K45/06 , A61K31/4025 , A61K31/4178 , A61K31/422 , A61K31/496 , A61K31/5377 , A61K31/665 , A61K31/4523
CPC classification number: A61K31/365 , A61K31/4025 , A61K31/4178 , A61K31/422 , A61K31/4523 , A61K31/496 , A61K31/5377 , A61K31/665 , A61K45/06
Abstract: The present invention provides compounds, pharmaceutical compositions and methods for the treatment of specific cancers. Such compositions may generally comprise a compound of formula (I): wherein R1-R3 are as defined herein, or pharmaceutically acceptable salts or esters thereof; and a pharmaceutically acceptable carrier.
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公开(公告)号：US08937056B2
公开(公告)日：2015-01-20
申请号：US13794635
申请日：2013-03-11
Applicant: Eisai R&D Management Co., Ltd.
Inventor： Sergei Agoulnik , Bruce Decosta , Hong Du , Yimin Jiang , Xiang-Yi Li , Kenichi Nomoto , John (Yuan) Wang , Huiming Zhang
IPC: A01N57/00 , A61K31/665 , A01N43/02 , A61K31/335 , A01N43/76 , A61K31/42 , A61K31/415 , A61K31/497 , A61K31/535 , A61K31/4178 , A61K31/365 , A61K31/422 , A61K31/5377 , A61K45/06 , A61K31/496 , A61K31/4025 , A61K31/4523
CPC classification number: A61K31/365 , A61K31/4025 , A61K31/4178 , A61K31/422 , A61K31/4523 , A61K31/496 , A61K31/5377 , A61K31/665 , A61K45/06
Abstract: The present invention provides compounds, pharmaceutical compositions and methods for the treatment of specific cancers. Such compositions may generally comprise a compound of formula (I): wherein R1-R3 are as defined herein, or pharmaceutically acceptable salts or esters thereof; and a pharmaceutically acceptable carrier.
Abstract translation: 本发明提供了用于治疗特定癌症的化合物，药物组合物和方法。 这样的组合物通常可以包含式（I）的化合物：其中R 1 -R 3如本文所定义，或其药学上可接受的盐或酯; 和药学上可接受的载体。
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公开(公告)号：US11160783B2
公开(公告)日：2021-11-02
申请号：US15960259
申请日：2018-04-23
Applicant: Eisai R&D Management Co., LTD.
Inventor： Sergei Agoulnik , Bruce Decosta , Hong Du , Yimin Jiang , Xiang-Yi Li , Kenichi Nomoto , John (Yuan) Wang , Huiming Zhang
IPC: A61K31/365 , A61P35/00 , A61K31/4025 , A61K31/4178 , A61K31/422 , A61K31/4523 , A61K31/496 , A61K31/5377 , A61K31/665 , A61K45/06
Abstract: The present invention provides compounds, pharmaceutical compositions and methods for the treatment of specific cancers. Such compositions may generally comprise a compound of formula (I): wherein R1-R3 are as defined herein, or pharmaceutically acceptable salts or esters thereof; and a pharmaceutically acceptable carrier.
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