公开(公告)号：US20230151360A1

公开(公告)日：2023-05-18

申请号：US17791343

申请日：2021-01-28

Applicant: Eisai R&D Management Co., Ltd.

Inventor： Yuta SUZUKI ,  Kazuto YAMAZAKI ,  Kenji KUBARA ,  Tomohiko TAMURA ,  Daisuke KUROTAKI

IPC: C12N15/11 ,  A61K47/54 ,  C12N15/113

CPC classification number: C12N15/111 ,  A61K47/549 ,  C12N15/113 ,  C12N2310/315 ,  C12N2310/351

Abstract: Disclosed is a nucleic acid complex or a pharmaceutically acceptable salt thereof; the nucleic acid complex represented by the formula (I), wherein X is CH2 or O; Y is a sugar ligand having mannose or GalNAc; n is an integer of 1 to 8; and Z is a group comprising an oligonucleotide.