公开(公告)号：US07241936B2

公开(公告)日：2007-07-10

申请号：US10705197

申请日：2003-11-12

申请人： Elena Babiychuk ,  Sergei Kushnir ,  Marc De Block

发明人： Elena Babiychuk ,  Sergei Kushnir ,  Marc De Block

IPC分类号： C12N15/82 ,  A01H5/00 ,  A01H5/10

CPC分类号： C12N15/8289 ,  C12N9/1077 ,  C12N15/8263 ,  Y10T436/143333

摘要： The invention provides for the use of isolated polynucleotides encoding maize poly (ADP-ribose) polymerase (PARP) proteins to produce eukaryotic cells and organisms, particularly plant cells and plants, with modified programmed cell death. Eukaryotic cells and organisms particularly plant cells and plants, are provided wherein either in at least part of the cells, preferably selected cells, the programmed cell death (PCD) is provoked, or wherein, on the contrary, PCD of the cells or of at least part of the cells in an organism is inhibited, by modulation of the level or activity or PARP proteins in those cells.

摘要翻译： 本发明提供编码玉米多聚（ADP-核糖）聚合酶（PARP）蛋白的分离的多核苷酸用于产生具有修饰的程序性细胞死亡的真核细胞和生物体，特别是植物细胞和植物的用途。 提供真核细胞和生物体，特别是植物细胞和植物，其中在至少部分细胞中，优选选择的细胞，程序性细胞死亡（PCD）被激发，或者相反地，细胞的PCD或 通过调节这些细胞中的水平或活性或PARP蛋白，抑制生物体中的最少部分细胞。

公开(公告)号：US20120164650A1

公开(公告)日：2012-06-28

申请号：US13244200

申请日：2011-09-23

申请人： Elena BABIYCHUK ,  Sergei Kushnir ,  Marc De Block

发明人： Elena BABIYCHUK ,  Sergei Kushnir ,  Marc De Block

IPC分类号： C12Q1/68 ,  C12N15/82 ,  G01N33/50

CPC分类号： C12N15/8289 ,  C12N9/1077 ,  C12N15/8263 ,  Y10T436/143333

摘要： The invention provides for the use of isolated polynucleotides encoding maize poly (ADP-ribose) polymerase (PARP) proteins to produce eukaryotic cells and organisms, particularly plant cells and plants, with modified programmed cell death. Eukaryotic cells and organisms particularly plant cells and plants, are provided wherein either in at least part of the cells, preferably selected cells, the programmed cell death (PCD) is provoked, or wherein, on the contrary, PCD of the cells or of at least part of the cells in an organism is inhibited, by modulation of the level or activity or PARP proteins in those cells.

摘要翻译： 本发明提供编码玉米多聚（ADP-核糖）聚合酶（PARP）蛋白的分离的多核苷酸用于产生具有修饰的程序性细胞死亡的真核细胞和生物体，特别是植物细胞和植物的用途。 提供真核细胞和生物体，特别是植物细胞和植物，其中在至少部分细胞中，优选选择的细胞，程序性细胞死亡（PCD）被激发，或者相反地，细胞的PCD或 通过调节这些细胞中的水平或活性或PARP蛋白，抑制生物体中的最少部分细胞。

公开(公告)号：US08058510B2

公开(公告)日：2011-11-15

申请号：US11802343

申请日：2007-05-22

申请人： Elena Babiychuk ,  Sergei Kushnir ,  Marc De Block

发明人： Elena Babiychuk ,  Sergei Kushnir ,  Marc De Block

IPC分类号： C12N15/82 ,  A01H5/00 ,  A01H5/10

CPC分类号： C12N15/8289 ,  C12N9/1077 ,  C12N15/8263 ,  Y10T436/143333

摘要： The invention provides for the use of isolated polynucleotides encoding maize poly (ADP-ribose) polymerase (PARP) proteins to produce eukaryotic cells and organisms, particularly plant cells and plants, with modified programmed cell death. Eukaryotic cells and organisms particularly plant cells and plants, are provided wherein either in at least part of the cells, preferably selected cells, the programmed cell death (PCD) is provoked, or wherein, on the contrary, PCD of the cells or of at least part of the cells in an organism is inhibited, by modulation of the level or activity or PARP proteins in those cells.

摘要翻译： 本发明提供编码玉米多聚（ADP-核糖）聚合酶（PARP）蛋白的分离的多核苷酸用于产生具有修饰的程序性细胞死亡的真核细胞和生物体，特别是植物细胞和植物的用途。 提供真核细胞和生物体，特别是植物细胞和植物，其中在至少部分细胞中，优选选择的细胞，程序性细胞死亡（PCD）被激发，或者相反地，细胞的PCD或 通过调节这些细胞中的水平或活性或PARP蛋白，抑制生物体中的最少部分细胞。

公开(公告)号：US20090205069A1

公开(公告)日：2009-08-13

申请号：US11802343

申请日：2007-05-22

申请人： Elena Babiychuk ,  Sergei Kushnir ,  Marc De Block

发明人： Elena Babiychuk ,  Sergei Kushnir ,  Marc De Block

IPC分类号： C12N15/82 ,  A01H5/00 ,  C07H21/04

CPC分类号： C12N15/8289 ,  C12N9/1077 ,  C12N15/8263 ,  Y10T436/143333

摘要： The invention provides for the use of isolated polynucleotides encoding maize poly (ADP-ribose) polymerase (PARP) proteins to produce eukaryotic cells and organisms, particularly plant cells and plants, with modified programmed cell death. Eukaryotic cells and organisms particularly plant cells and plants, are provided wherein either in at least part of the cells, preferably selected cells, the programmed cell death (PCD) is provoked, or wherein, on the contrary, PCD of the cells or of at least part of the cells in an organism is inhibited, by modulation of the level or activity or PARP proteins in those cells.

摘要翻译： 本发明提供编码玉米多聚（ADP-核糖）聚合酶（PARP）蛋白的分离的多核苷酸用于产生具有修饰的程序性细胞死亡的真核细胞和生物体，特别是植物细胞和植物的用途。 提供真核细胞和生物体，特别是植物细胞和植物，其中在至少部分细胞中，优选选择的细胞，程序性细胞死亡（PCD）被激发，或者相反地，细胞的PCD或 通过调节这些细胞中的水平或活性或PARP蛋白，抑制生物体中的最少部分细胞。

公开(公告)号：US06693185B2

公开(公告)日：2004-02-17

申请号：US09118276

申请日：1998-07-17

申请人： Elena Babiychuk ,  Sergei Kushnir ,  Marc De Block

发明人： Elena Babiychuk ,  Sergei Kushnir ,  Marc De Block

IPC分类号： C12N1529

CPC分类号： C12N15/8289 ,  C12N9/1077 ,  C12N15/8263 ,  Y10T436/143333

摘要： The invention provides for the use of isolated polynucleotides encoding maize poly (ADP-ribose) polymerase (PARP) proteins to produce eukaryotic cells and organisms, particularly plant cells and plants, with modified programmed cell death. Eukaryotic cells and organisms particularly plant cells and plants, are provided wherein either in at least part of the cells, preferably selected cells, the programmed cell death (PCD) is provoked, or wherein, on the contrary, PCD of the cells or of at least part of the cells in an organism is inhibited, by modulation of the level or activity or PARP proteins in those cells.