公开(公告)号：US20240424175A1

公开(公告)日：2024-12-26

申请号：US18672288

申请日：2024-05-23

Applicant: Elixir Medical Corporation

Inventor： John YAN ,  Xiaoxia ZHENG ,  Vinayak D. BHAT ,  Motasim SIRHAN

IPC: A61L31/16 ,  A61L31/08

Abstract: Devices, systems, and methods are provided including a structure having one or more surfaces configured for internal use within a patient's body and one or more therapeutic compositions comprising one or more active substances including at least one of a chelating agent, a direct factor Xa inhibitor, a direct factor IIa inhibitor, and a factor XI/XIa inhibitor disposed in or on the structure. The structure is configured to be positioned adjacent a target site in the patient's body. The therapeutic composition is formulated to release the one or more active substances to the target site to provide one or more of inhibit clot formation, promote clot dissolution, inhibit or dissolute inflammation, inhibit vessel injury, increase time before clotting, and/or inhibit cell proliferation. Delayed or other controlled release of the therapeutic composition from the structure may be provided.

公开(公告)号：US20250127529A1

公开(公告)日：2025-04-24

申请号：US18918647

申请日：2024-10-17

Applicant: Elixir Medical Corporation

Inventor： Motasim SIRHAN ,  Benjamyn SERNA ,  John YAN ,  Bozena TREADWELL ,  Russell PONG

IPC: A61B17/22 ,  A61B17/00

Abstract: Balloon catheters, sleeves, cages, cylindrical structures and endoluminal prostheses are provided with stress-applying and spacing features coupled to expandable surfaces thereof. At least one or at least some stress-applying features are immobilized onto the surface or into pre-formed indentations formed in the expandable surface. The stress-applying and spacing features may have blunt and/or rounded contact regions which contact tissue or calcified regions in the vasculature. The contact regions dent or fracture occlusive material on the wall of a vascular lumen and/or patient valve leaflets when expanded. The spacing of features can permit blood, drug, and contrast perfusion past structures expanded in the vasculature, particularly balloon catheters.

公开(公告)号：US20220183843A1

公开(公告)日：2022-06-16

申请号：US17684874

申请日：2022-03-02

Applicant: Elixir Medical Corporation

Inventor： Motasim SIRHAN ,  John YAN ,  Vinayak BHAT ,  Joseph PARASCHAC ,  Benjamyn SERNA

IPC: A61F2/24

Abstract: A catheter system for delivering an anchor to a valve annulus in a heart valve includes a locating catheter and an anchor delivery catheter. The locating catheter has a distal end which can be advanced beneath the valve annulus near a target site on an upper surface of the valve annulus. The anchor delivery catheter has a distal end which can be advanced over the valve annulus to deliver an anchor along a delivery path to the target site. The distal end of the locating catheter has at least one magnetic element, and the distal end of the anchor delivery catheter has at least one magnetic element which attracts the at least one magnetic element on the locating catheter to pivotally couple the distal end of the anchor delivery catheter to the distal end of the locating catheter. In this way, the deliver catheter can be pivoted relative to the locating catheter to orient the delivery path away from the locating catheter.