公开(公告)号：US20240424175A1

公开(公告)日：2024-12-26

申请号：US18672288

申请日：2024-05-23

Applicant: Elixir Medical Corporation

Inventor： John YAN ,  Xiaoxia ZHENG ,  Vinayak D. BHAT ,  Motasim SIRHAN

IPC: A61L31/16 ,  A61L31/08

Abstract: Devices, systems, and methods are provided including a structure having one or more surfaces configured for internal use within a patient's body and one or more therapeutic compositions comprising one or more active substances including at least one of a chelating agent, a direct factor Xa inhibitor, a direct factor IIa inhibitor, and a factor XI/XIa inhibitor disposed in or on the structure. The structure is configured to be positioned adjacent a target site in the patient's body. The therapeutic composition is formulated to release the one or more active substances to the target site to provide one or more of inhibit clot formation, promote clot dissolution, inhibit or dissolute inflammation, inhibit vessel injury, increase time before clotting, and/or inhibit cell proliferation. Delayed or other controlled release of the therapeutic composition from the structure may be provided.