公开(公告)号：US11427814B2

公开(公告)日：2022-08-30

申请号：US17213169

申请日：2021-03-25

申请人： Encodia, Inc.

发明人： Kevin Desai ,  Kevin L. Gunderson ,  Robert C. James ,  Lei Shi ,  Stephen Verespy, III

IPC分类号： C12N9/48 ,  C12P21/06

摘要： Provided herein are modified cleavases for removing amino acids from peptides, polypeptides, and proteins. Also provided are methods of using the modified cleavases for treating polypeptides, and kits comprising the modified cleavase. In some embodiments, the methods and the kits also include other components for macromolecule sequencing and/or analysis.

公开(公告)号：US11788080B2

公开(公告)日：2023-10-17

申请号：US17850516

申请日：2022-06-27

申请人： Encodia, Inc.

发明人： Kevin Desai ,  Kevin L. Gunderson ,  Robert C. James ,  Lei Shi ,  Stephen Verespy, III

IPC分类号： C12N9/48 ,  C12P21/06

CPC分类号： C12N9/485 ,  C12P21/06

摘要： Provided herein are modified cleavases for removing amino acids from peptides, polypeptides, and proteins. Also provided are methods of using the modified cleavases for treating polypeptides, and kits comprising the modified cleavase. In some embodiments, the methods and the kits also include other components for macromolecule sequencing and/or analysis.