公开(公告)号：US07087402B2

公开(公告)日：2006-08-08

申请号：US10205957

申请日：2002-07-26

申请人： Miguel Angel Fuenzalida Diaz ,  Alejandro Markovits Rojas ,  Endre Markovits Schersl ,  Irene Martinez Basterrechea

发明人： Miguel Angel Fuenzalida Diaz ,  Alejandro Markovits Rojas ,  Endre Markovits Schersl ,  Irene Martinez Basterrechea

IPC分类号： C12P33/00 ,  C12P7/64

CPC分类号： C12P7/6436 ,  C12P33/00

摘要： The present invention is related to a process for selectively transesterifying stanols in mixtures comprising sterols and stanols, and a process for separating sterols from said mixtures.The process of selective transesterification comprises the forming of a reacting mixture by contacting a selective lipase with a reactant mixture comprising sterols and stanols and an ester selected from the group consisting of esters of an organic acid with a short chain aliphatic alcohol. The transetrifying is carried out agitated reactors at pressures below atmospheric pressure and temperatures from 30 to 90° C.The process for separating a fraction comprising sterols from a mixture comprising sterols and stanols comprises the steps: a) forming a reactive mixture by contacting a selective lipase with a reactant mixture comprising sterols and stanols and an ester selected from the group consisting of esters of an organic acid with a short chain aliphatic alcohol; b) forming a reacted mixture by separating the selective lipase from the reacting; and c) separating from the reacted mixture a fraction comprising sterols The reaction is carried out in agitated reactors at pressures below atmospheric pressure and temperatures from 30 to 90° C.Recovering from the reacted mixture of a fraction comprising sterols comprise one or more distillation steps at reduced pressure or one or more distillation and crystallization steps.

公开(公告)号：US07078544B2

公开(公告)日：2006-07-18

申请号：US10205964

申请日：2002-07-26

申请人： Miguel Angel Fuenzalida Diaz ,  Alejandro Markovits Rojas ,  Endre Markovits Schersl ,  Irene Martinez Basterrechea

发明人： Miguel Angel Fuenzalida Diaz ,  Alejandro Markovits Rojas ,  Endre Markovits Schersl ,  Irene Martinez Basterrechea

IPC分类号： C07J9/00 ,  C12P33/00

CPC分类号： C12P7/6436 ,  C07J1/00 ,  C12N9/20 ,  C12P7/62 ,  C12P33/00

摘要： A process for producing steryl or stanyl esters, comprises the steps of: a) forming a reacting mixture by contacting a lipase with a reactant mixture wherein the reactant mixture comprise sterols or stanols and one or more esters selected from the group consisting of esters of a fatty acid with a short chain aliphatic alcohol; b) separating the lipase from the reacting mixture to form a reacted mixture; and c) separating steryl or stanyl esters from the reacted mixture. The reaction is carried out in stirred reactors at pressures below atmospheric pressure and temperatures from 30 to 90° C. The separation of esters from the reacted mixtures is carried out by distillation at low pressures.A process for esterifying sterols or stanols comprise forming a reacting mixture by contacting a lipase with a reactant mixture wherein the reactant mixture comprise sterols or stanols and one or more esters selected from the group consisting of esters of a fatty acid with a short chain aliphatic alcohol. The reaction of esterification is carried out in stirred reactors at pressures below atmospheric pressure and temperatures from 30 to 90° C.

公开(公告)号：US06465665B1

公开(公告)日：2002-10-15

申请号：US09654410

申请日：2000-09-01

申请人： Endre Markovits Schersl

发明人： Endre Markovits Schersl

IPC分类号： C07J900

CPC分类号： C07J9/00

摘要： A high efficiency continuous process for the recovering high purity sterol mixtures from mixtures of neutral compounds obtained form black liquor soap skimings of the cellulose pulping industry or from tall oil pitch comprising the steps of distillation, crystallization and recirculation of the mother liquor residue.

摘要翻译： 用于从纤维素制浆工业的黑液皂脱脂获得的中性化合物混合物中回收高纯度固醇混合物的高效连续方法，或由妥尔油沥青包括蒸馏，结晶和再循环母液残余物的步骤。

公开(公告)号：US06297353B1

公开(公告)日：2001-10-02

申请号：US09294303

申请日：1999-04-19

申请人： Miguel Angel Fuenzalida Diaz ,  Alejandro Markovits Rojas ,  Roberto Benito Leiva Hinojosa ,  Endre Markovits Schersl

发明人： Miguel Angel Fuenzalida Diaz ,  Alejandro Markovits Rojas ,  Roberto Benito Leiva Hinojosa ,  Endre Markovits Schersl

IPC分类号： C08F100

CPC分类号： C11B13/005 ,  B01D1/22 ,  B01D3/12 ,  B01D3/146 ,  Y02W30/74

摘要： A method for obtaining neutral compounds from black-liquor soaps, tall oil and tall oil by-products is disclosed. The method includes the steps of: (1) dehydrating black liquor soaps, neutralized tall oil, or neutralized tall oil by-products to form a dehydrated current; (2) distilling the dehydrated current in a distillation column; (3) collecting an essentially soap free distillate; and (4) collecting an essentially neutral compound free residue. Also disclosed is a method for obtaining a sterol concentrate from black-liquor soap solutions, neutralized tall oil, or neutralized tall oil by-products. In this method, a distillation operation is repeated until a current of sterols with the desired purity is obtained. The method yields a sterol concentrate with a level of purity over 96%. In another version of the method, a high purity sterol cocentrate is achieved by vacuum fractionation

摘要翻译： 公开了从黑液皂，妥尔油和妥尔油副产物中获得中性化合物的方法。 该方法包括以下步骤：（1）将黑液皂，中和的妥尔油或中和的妥尔油副产物脱水形成脱水电流; （2）蒸馏塔中的脱水电流; （3）收集基本上无皂的馏出物; 和（4）收集基本上中性的化合物残留物。 还公开了从黑液皂溶液，中和的妥尔油或中和的妥尔油副产物中获得固醇浓缩物的方法。 在该方法中，重复蒸馏操作，直到获得具有所需纯度的甾醇的电流。 该方法产生纯度超过96％的固醇浓缩物。 在该方法的另一个版本中，通过真空分级来获得高纯度的甾醇浓缩物