公开(公告)号：US20160331771A1

公开(公告)日：2016-11-17

申请号：US15041813

申请日：2016-02-11

Applicant: EpicentRx, Inc.

Inventor： Bryan T. Oronsky ,  Peter Langecker

IPC: A61K31/7048 ,  A61K31/593 ,  A61K47/42 ,  A61K45/06 ,  A61K9/00

CPC classification number: A61K31/7048 ,  A61K9/0014 ,  A61K31/593 ,  A61K45/06 ,  A61K47/42 ,  A61K47/60 ,  A61K47/643 ,  A61K2300/00

Abstract: Provided are methods and compositions for treating and preventing hyperproliferative disorders such as psoriasis by administration of a cardiac glycoside alone or in combination locally or systemically with a calciotropic agents and/or a diffusion-limiting component, such a vasoconstrictor or collagen barrier.

Abstract translation: 本发明提供了通过单独施用强心苷或局部或全身组合使用光致剂和/或扩散限制成分如血管收缩剂或胶原屏障来治疗和预防过度增殖性疾病如牛皮癣的方法和组合物。