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公开(公告)号：US09855275B2
公开(公告)日：2018-01-02
申请号：US15598078
申请日：2017-05-17
Applicant: Epizyme, Inc.
Inventor： Kevin W. Kuntz , Richard Chesworth , Kenneth W. Duncan , Heike Keilhack , Natalie Warholic , Christine Klaus , Sarah K. Knutson , Timothy J. N. Wigle , Masashi Seki , Syuji Shirotori , Satoshi Kawano
IPC: A61K31/5377 , A61K31/444 , A61K31/506 , A61K31/4412 , A61K31/553 , A61K31/551 , C07D213/64 , C07D409/12 , C07D405/12 , C07D413/12 , C07D417/12 , C07D491/08 , C07D491/107 , C07D405/14 , C07D498/08 , A61K31/496 , A61K31/4709 , A61K31/4545 , A61K31/4439 , A61K31/4436 , A61K31/4433 , A61K31/443 , C07D401/12
CPC classification number: A61K31/5377 , A61K31/4412 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/4709 , A61K31/496 , A61K31/506 , A61K31/551 , A61K31/553 , C07D213/64 , C07D401/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D491/08 , C07D491/107 , C07D498/08
Abstract: The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
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公开(公告)号：US10420775B2
公开(公告)日：2019-09-24
申请号：US15816907
申请日：2017-11-17
Applicant: Epizyme, Inc.
Inventor： Kevin W. Kuntz , Richard Chesworth , Kenneth W. Duncan , Heike Keilhack , Natalie Warholic , Christine Klaus , Sarah K. Knutson , Timothy J. N. Wigle , Masashi Seki , Syuji Shirotori , Satoshi Kawano
IPC: A61K31/5377 , A61K31/444 , A61K31/506 , A61K31/4412 , A61K31/553 , A61K31/551 , C07D213/64 , C07D409/12 , C07D498/08 , C07D401/12 , C07D405/12 , C07D413/12 , C07D417/12 , C07D491/08 , C07D491/107 , C07D405/14 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/4545 , A61K31/4709 , A61K31/496
Abstract: The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
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Patent Agency Ranking
公开(公告)号：US11052093B2
公开(公告)日：2021-07-06
申请号：US16660339
申请日：2019-10-22
Applicant: Epizyme, Inc.
Inventor： Kevin W. Kuntz , Richard Chesworth , Kenneth W. Duncan , Heike Keilhack , Natalie Warholic , Christine Klaus , Sarah K. Knutson , Timothy J. N. Wigle , Masashi Seki , Syuji Shirotori , Satoshi Kawano
IPC: A61K31/5377 , A61K31/444 , A61K31/506 , A61K31/4412 , A61K31/553 , A61K31/551 , C07D213/64 , C07D409/12 , C07D498/08 , C07D401/12 , C07D405/12 , C07D413/12 , C07D417/12 , C07D491/08 , C07D491/107 , C07D405/14 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/4545 , A61K31/4709 , A61K31/496
Abstract: The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
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公开(公告)号：US12168015B2
公开(公告)日：2024-12-17
申请号：US18606925
申请日：2024-03-15
Applicant: Epizyme, Inc.
Inventor： Kevin W. Kuntz , Richard Chesworth , Kenneth W. Duncan , Heike Keilhack , Natalie Warholic , Christine Klaus , Sarah K. Knutson , Timothy J. N. Wigle , Masashi Seki , Syuji Shirotori , Satoshi Kawano
IPC: A61K31/5377 , A61K31/4412 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/4709 , A61K31/496 , A61K31/506 , A61K31/551 , A61K31/553 , C07D213/64 , C07D401/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D491/08 , C07D491/107 , C07D498/08
Abstract: The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
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公开(公告)号：US20160332969A1
公开(公告)日：2016-11-17
申请号：US15162453
申请日：2016-05-23
Applicant: Epizyme, Inc.
Inventor： Kevin W. Kuntz , Richard Chesworth , Kenneth W. Duncan , Heike Keilhack , Natalie Warholic , Christine Klaus , Sarah K. Knutson , Timothy J. N. Wigle , Masashi Seki
IPC: C07D213/64 , C07D405/12 , C07D491/113 , C07D491/048 , C07D405/14 , C07D409/12 , C07D491/08 , C07D401/12 , C07D401/14
Abstract: The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
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公开(公告)号：US12168016B2
公开(公告)日：2024-12-17
申请号：US18606946
申请日：2024-03-15
Applicant: Epizyme, Inc.
Inventor： Kevin W. Kuntz , Richard Chesworth , Kenneth W. Duncan , Heike Keilhack , Natalie Warholic , Christine Klaus , Sarah K. Knutson , Timothy J. N. Wigle , Masashi Seki , Syuji Shirotori , Satoshi Kawano
IPC: A61K31/5377 , A61K31/4412 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/4709 , A61K31/496 , A61K31/506 , A61K31/551 , A61K31/553 , C07D213/64 , C07D401/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D491/08 , C07D491/107 , C07D498/08
Abstract: The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
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公开(公告)号：US12161645B2
公开(公告)日：2024-12-10
申请号：US18606903
申请日：2024-03-15
Applicant: Epizyme, Inc.
Inventor： Kevin W. Kuntz , Richard Chesworth , Kenneth W. Duncan , Heike Keilhack , Natalie Warholic , Christine Klaus , Sarah K. Knutson , Timothy J. N. Wigle , Masashi Seki , Syuji Shirotori , Satoshi Kawano
IPC: A61K31/5377 , A61K31/4412 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/4709 , A61K31/496 , A61K31/506 , A61K31/551 , A61K31/553 , C07D213/64 , C07D401/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D491/08 , C07D491/107 , C07D498/08
Abstract: The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
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