专利检索 ap:("Eric J. Kunkel" OR "Elen S. Rosler" OR "Sylvie Private" OR "Jennifer E. Melrose") AND inv:"Sylvie Private" 第 1 页

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发明申请
METHODS FOR IDENTIFYING AGENTS AND THEIR USE FOR THE PREVENTION OR STABILIZATION OF FIBROSIS 审中-公开
标题翻译：鉴别药物的方法及其用于预防或稳定纤维化的用途

公开(公告)号：US20100093613A1

公开(公告)日：2010-04-15

申请号：US12530582

申请日：2008-03-10

申请人： Eric J. Kunkel , Elen S. Rosler , Sylvie Private , Jennifer E. Melrose

发明人： Eric J. Kunkel , Elen S. Rosler , Sylvie Private , Jennifer E. Melrose

IPC分类号： C12Q1/68 , C12Q1/02 , A61K31/4184 , A61K31/44 , A61K31/335 , A61K38/12 , A61K31/343 , A61K31/352 , A61K31/196 , A61K31/50 , A61P21/00

CPC分类号： G01N33/6893 , G01N33/5055 , G01N33/5064 , G01N33/5067 , G01N2800/085 , G01N2800/10 , G01N2800/382

摘要： Agents that stabilize and/or prevent fibrosis are identified by assaying test agents in a battery of assays to measure the effect of the test agent on matrix deposition and remodeling, epithelial health, and inflammation. Treatment for fibrosis is provided using compositions of the invention.

摘要翻译： 稳定和/或预防纤维化的药物通过在测定电池中测定试剂来测定测试剂对基质沉积和重塑，上皮健康和炎症的影响来鉴定。使用本发明的组合物提供纤维化的治疗。