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公开(公告)号：US5843144A
公开(公告)日：1998-12-01
申请号：US494320
申请日：1995-06-26
申请人： Eric N. Rudie , Mitchell Dann , John M. Reid , Bruce H. Neilson , James V. Kauphusman , James E. Burgett , Stanley E. Kluge , Steven W. Norsted
发明人： Eric N. Rudie , Mitchell Dann , John M. Reid , Bruce H. Neilson , James V. Kauphusman , James E. Burgett , Stanley E. Kluge , Steven W. Norsted
CPC分类号： A61B18/1815 , A61B18/18
摘要： A method for treating an individual with diseased prostatic tissue, such as benign prostatic hyperplasia, includes inserting a catheter into a urethra to position a microwave antenna located within the catheter adjacent a prostatic region of the urethra. A microwave antenna is then driven within a power range for applying microwave energy substantially continuously to prostatic tissue to heat the prostatic tissue surrounding the microwave antenna at a temperature and for a time period sufficient to cause necrosis of the prostatic tissue.
摘要翻译： 用于治疗具有患病前列腺组织（例如良性前列腺增生）的个体的方法包括将导管插入尿道以将位于尿道前列腺区域附近的微波天线定位。 然后在功率范围内驱动微波天线，以将微波能量基本连续地施加到前列腺组织，以在足以引起前列腺组织坏死的温度和时间段加热微波天线周围的前列腺组织。
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公开(公告)号：US5413588A
公开(公告)日：1995-05-09
申请号：US847718
申请日：1992-03-06
CPC分类号： A61B18/18 , A61B18/1815 , A61N5/02 , A61N5/04 , A61N5/045 , A61B2017/00274 , A61B2018/00547 , A61M25/10
摘要： An intraurethral, Foley-type catheter shaft contains a microwave antenna capable of generating a cylindrically symmetrical thermal pattern, within which temperatures are capable of exceeding 45.degree. C. The antenna, which is positioned within the shaft, is surrounded by means within the shaft for absorbing thermal energy conducted by the tissue and asymmetrically absorbing electromagnetic energy emitted by the antenna--a greater amount of electromagnetic energy being absorbed on one side of the shaft. This asymmetrical absorption alters the thermal pattern generated by the microwave antenna, making it cylindrically asymmetrical, which effectively focuses microwave thermal therapy toward undesirous benign tumorous tissue growth of a prostate anterior and lateral to the urethra, and away from healthy tissue posterior to the urethra.
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公开(公告)号：US5755754A
公开(公告)日：1998-05-26
申请号：US684471
申请日：1996-07-19
CPC分类号： A61B18/18 , A61B18/1815 , A61N5/02 , A61N5/04 , A61N5/045 , A61B2017/00274 , A61B2018/00547 , A61M25/10
摘要： An intraurethral, Foley-type catheter shaft contains a microwave antenna capable of generating a cylindrically symmetrical thermal pattern, within which temperatures are capable of exceeding 45.degree. C. The antenna, which is positioned within the shaft, is surrounded by means within the shaft for absorbing thermal energy conducted by the tissue and asymmetrically absorbing electromagnetic energy emitted by the antenna--a greater amount of electromagnetic energy being absorbed on one side of the shaft. This asymmetrical absorption alters the thermal pattern generated by the microwave antenna, making it cylindrically asymmetrical, which effectively focuses microwave thermal therapy toward undesirous benign tumorous tissue growth of a prostate anterior and lateral to the urethra, and away from healthy tissue posterior to the urethra.
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4.发明授权Device and method for asymmetrical thermal therapy with helical dipole microwave antenna 失效用螺旋偶极微波天线进行非对称热疗的装置和方法
公开(公告)号：US5916241A
公开(公告)日：1999-06-29
申请号：US903051
申请日：1997-07-30
CPC分类号： A61B18/18 , A61B18/1815 , A61N5/02 , A61N5/04 , A61N5/045 , A61B2017/00274 , A61B2018/00547 , A61M25/10
摘要： An intraurethral, Foley-type catheter shaft contains a microwave antenna capable of generating a cylindrically symmetrical thermal pattern, within which temperatures are capable of exceeding 45.degree. C. The antenna, which is positioned within the shaft, is surrounded by means within the shaft for absorbing thermal energy conducted by the tissue and asymmetrically absorbing electromagnetic energy emitted by the antenna--a greater amount of electromagnetic energy being absorbed on one side of the shafts. This asymmetrical absorption alters the thermal pattern generated by the microwave antenna, making it cylindrically asymmetrical, which effectively focuses microwave thermal therapy toward undesirous benign tumorous tissue growth of a prostate anterior and lateral to the urethra, and away from healthy tissue posterior to the urethra.
摘要翻译： 尿道内的Foley型导管轴包含能够产生圆柱形对称热图案的微波天线，其中温度可以超过45℃。定位在轴内的天线由轴内的装置包围， 吸收由组织传导的热能并且不对称地吸收由天线发射的电磁能量 - 在轴的一侧上吸收更多量的电磁能。 这种不对称吸收改变了由微波天线产生的热图，使其成圆柱形不对称，这有效地将微波热治疗聚焦到尿道前列腺前列腺前列腺前列腺良性肿瘤组织生长，远离尿道后方的健康组织。
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5.发明授权Device and method for asymmetrical thermal therapy with helical dipole microwave antenna 失效用螺旋偶极微波天线进行非对称热疗的装置和方法
公开(公告)号：US5464445A
公开(公告)日：1995-11-07
申请号：US208642
申请日：1994-03-09
CPC分类号： A61B18/18 , A61B18/1815 , A61N5/02 , A61N5/04 , A61N5/045 , A61B2017/00274 , A61B2018/00547 , A61M25/10
摘要： An intraurethral, Foley-type catheter shaft contains a microwave antenna capable of generating a cylindrically symmetrical thermal pattern, within which temperatures are capable of exceeding 45.degree. C. The antenna, which is positioned within the shaft, is surrounded by means within the shaft for absorbing thermal energy conducted by the tissue and asymmetrically absorbing electromagnetic energy emitted by the antenna--a greater amount of electromagnetic energy being absorbed on one side of the shaft. This asymmetrical absorption alters the thermal pattern generated by the microwave antenna, making it cylindrically asymmetrical, which effectively focuses microwave thermal therapy toward undesirous benign tumorous tissue growth of a prostate anterior and lateral to the urethra, and away from healthy tissue posterior to the urethra.
摘要翻译： 尿道内的Foley型导管轴包含能够产生圆柱形对称热图案的微波天线，其中温度可以超过45℃。定位在轴内的天线由轴内的装置包围， 吸收由组织传导的热能并且不对称地吸收天线发射的电磁能量 - 在轴的一侧上吸收更大量的电磁能。 这种不对称吸收改变了由微波天线产生的热图，使其成圆柱形不对称，这有效地将微波热治疗聚焦到尿道前列腺前列腺前列腺前列腺良性肿瘤组织生长，远离尿道后方的健康组织。
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公开(公告)号：US5916240A
公开(公告)日：1999-06-29
申请号：US892758
申请日：1997-07-15
CPC分类号： A61B18/18 , A61B18/1815 , A61N5/02 , A61N5/04 , A61N5/045 , A61B2017/00274 , A61B2018/00547 , A61M25/10
摘要： An intraurethral, Foley-type catheter shaft contains a microwave antenna capable of generating a cylindrically symmetrical thermal pattern, within which temperatures are capable of exceeding 45.degree. C. The antenna, which is positioned within the shaft, is surrounded by means within the shaft for absorbing thermal energy conducted by the tissue and asymmetrically absorbing electromagnetic energy emitted by the antenna--a greater amount of electromagnetic energy being absorbed on one side of the shaft. This asymmetrical absorption alters the thermal pattern generated by the microwave antenna, making it cylindrically asymmetrical, which effectively focuses microwave thermal therapy toward undesirous benign tumorous tissue growth of a prostate anterior and lateral to the urethra, and away from healthy tissue posterior to the urethra.
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公开(公告)号：US5326343A
公开(公告)日：1994-07-05
申请号：US847718
申请日：1992-03-06
摘要： An intraurethral, Foley-type catheter shaft contains a microwave antenna capable of generating a cylindrically symmetrical thermal pattern, within which temperatures are capable of exceeding 45.degree. C. The antenna, which is positioned within the shaft, is surrounded by means within the shaft for absorbing thermal energy conducted by the tissue and asymmetrically absorbing electromagnetic energy emitted by the antenna--a greater amount of electromagnetic energy being absorbed on one side of the shaft. This asymmetrical absorption alters the thermal pattern generated by the microwave antenna, making it cylindrically asymmetrical, which effectively focuses microwave thermal therapy toward undesirous benign tumorous tissue growth of a prostate anterior and lateral to the urethra, and away from healthy tissue posterior to the urethra.
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8.发明授权Device for asymmetrical thermal therapy with helical dipole microwave antenna 失效用螺旋偶极微波天线进行不对称热疗的装置
公开(公告)号：US5545137A
公开(公告)日：1996-08-13
申请号：US413392
申请日：1995-03-30
CPC分类号： A61B18/18 , A61B18/1815 , A61N5/02 , A61N5/04 , A61N5/045 , A61B2017/00274 , A61B2018/00547 , A61M25/10
摘要： An intraurethral, Foley-type catheter shaft contains a microwave antenna capable of generating a cylindrically symmetrical thermal pattern, within which temperatures are capable of exceeding 45.degree. C. The antenna, which is positioned within the shaft, is surrounded by means within the shaft for absorbing thermal energy conducted by the tissue and asymmetrically absorbing electromagnetic energy emitted by the antenna--a greater amount of electromagnetic energy being absorbed on one side of the shaft. This asymmetrical absorption alters the thermal pattern generated by the microwave antenna, making it cylindrically asymmetrical, which effectively focuses microwave thermal therapy toward undesirous benign tumorous tissue growth of a prostate anterior and lateral to the urethra, and away from healthy tissue posterior to the urethra.
摘要翻译： 尿道内的Foley型导管轴包含能够产生圆柱形对称热图案的微波天线，其中温度可以超过45℃。定位在轴内的天线由轴内的装置包围， 吸收由组织传导的热能并且不对称地吸收天线发射的电磁能量 - 在轴的一侧上吸收更大量的电磁能。 这种不对称吸收改变了由微波天线产生的热图，使其成圆柱形不对称，这有效地将微波热治疗聚焦到尿道前列腺前列腺前列腺前列腺良性肿瘤组织生长，远离尿道后方的健康组织。
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9.发明授权Method for treating interstitial tissue associated with microwave thermal therapy 失效治疗与微波热疗相关的间质组织的方法
公开(公告)号：US5330518A
公开(公告)日：1994-07-19
申请号：US847894
申请日：1992-03-06
申请人： Bruce H. Neilson , Eric N. Rudie , Mitchell Dann
发明人： Bruce H. Neilson , Eric N. Rudie , Mitchell Dann
CPC分类号： A61B18/18 , A61B18/1815 , A61B2017/00057 , A61B2017/00084 , A61B2017/00274 , A61B2017/00292 , A61B2017/22069 , A61B2018/00011 , A61B2018/00547
摘要： A method of selectively treating interstitial tissue following microwave thermal therapy includes an intraurethral Foley-type catheter shaft. The catheter shaft contains a microwave antenna which is capable of generating a cylindrically symmetrical thermal pattern in tissue, within which temperatures are capable of exceeding 45.degree. C. The antenna is surrounded by means within the shaft for asymmetrically absorbing electromagnetic energy emitted by the antenna so as to concentrate thermal energy on a first side of the shaft. This asymmetrical absorption alters the thermal pattern generated by the microwave antenna, making it possible to focus microwave thermal therapy toward undesirous tissue and away from healthy tissue. The absorption means is also capable of absorbing heat from adjacent tissue by thermal conduction. Operation of the absorption means upon the conclusion of microwave thermal therapy aids in reducing edema of the treated tissues caused by the elevated temperatures of those tissues.
摘要翻译： 微波治疗后选择性治疗间质组织的方法包括尿道内Foley型导管轴。 导管轴包含能够在组织中产生圆柱对称热图案的微波天线，其中温度可以超过45℃。天线被轴内的装置包围，用于不对称地吸收由天线发射的电磁能量 以将热能集中在轴的第一侧上。 这种不对称吸收改变了由微波天线产生的热图，使得可以将微波热治疗聚焦到不想要的组织并远离健康组织。 吸收装置还能够通过热传导从相邻组织吸收热量。 在微波热疗结束时，吸收手段的操作有助于减少由这些组织升高的温度引起的治疗组织的水肿。
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10.发明授权
公开(公告)号：US5370677A
公开(公告)日：1994-12-06
申请号：US123321
申请日：1993-09-17
申请人： Eric N. Rudie , Stanley E. Kluge
发明人： Eric N. Rudie , Stanley E. Kluge
CPC分类号： A61B18/1815 , A61B18/18 , A61N5/02 , A61N5/045 , A61B2018/00523
摘要： A catheter shaft carries a coaxial cable, the terminal end of which contains a dipole antenna with opposing first and second helical elements. The first and second helical elements originate from a common connection to an outer conductor of the coaxial cable. The first and second helical elements are formed by winding flat wire around an outer insulator of the coaxial cable near a terminal end of the coaxial cable. A tubular-shaped capacitor is connected between an inner conductor of the coaxial cable and a point on the second helical element where the resistive component of the antenna's impedance matches the characteristic impedance of the coaxial cable. This match minimizes reflective losses of the antenna, thereby maximizing power transfer to the antenna. The antenna has an effective electrical length which is equal to one half the wavelength of the radiation emitted, independent of the physical length of the antenna. The antenna also has a radiation length which can be adjusted by varying the number and pitch of turns of the flat wire and the location of the impedance matching point.
摘要翻译： 导管轴携带同轴电缆，其同轴电缆的末端包含具有相对的第一和第二螺旋元件的偶极天线。 第一和第二螺旋元件源自与同轴电缆的外部导体的公共连接。 第一和第二螺旋元件通过在同轴电缆的末端附近绕着同轴电缆的外绝缘体缠绕扁线而形成。 管状电容器连接在同轴电缆的内部导体和第二螺旋元件上的点之间，其中天线阻抗的电阻分量与同轴电缆的特性阻抗匹配。 该匹配使天线的反射损耗最小化，从而最大化对天线的功率传输。 天线具有等于辐射发射波长的一半的有效电长度，与天线的物理长度无关。 该天线还具有可以通过改变扁平线的匝数和间距以及阻抗匹配点的位置来调整的辐射长度。
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