公开(公告)号：US20090192599A1

公开(公告)日：2009-07-30

申请号：US12419059

申请日：2009-04-06

申请人： Ernest Lane ,  Shouyan Lee ,  Charles Huang

发明人： Ernest Lane ,  Shouyan Lee ,  Charles Huang

IPC分类号： A61F2/24

CPC分类号： A61F2/2412 ,  A61F2/2409

摘要： A prosthetic heart valve assembly includes a gasket member and a valve member including a plurality of fasteners and a plurality of engagement members corresponding to the fasteners. The fasteners and/or engagement members may be configured to guide the engagement members into engagement with the fasteners. For example, the fasteners may include U-shaped spring-biased clips, e.g., attached to a core or other portion of a sewing cuff of the gasket member, and the engagement members may include latches or barbed protrusions that engage one or more holes in the fasteners. During use, the gasket member is introduced into a tissue annulus, and secured to the annulus, e.g., using a plurality of clips directed through the sewing cuff. The valve member is then introduced into the annulus and the engagement members are snapped or otherwise guided into engagement with the fasteners to secure the valve member relative to the gasket member.

摘要翻译： 假体心脏瓣膜组件包括垫圈构件和包括多个紧固件和对应于紧固件的多个接合构件的阀构件。 紧固件和/或接合构件可构造成引导接合构件与紧固件接合。 例如，紧固件可以包括U形弹簧偏置的夹子，例如，附接到垫圈构件的缝合箍的芯部或其他部分，并且接合构件可包括接合一个或多个孔的闩锁或有倒钩的突起 紧固件。 在使用期间，垫圈构件被引入到组织环中，并且例如通过使用穿过缝合袖带的多个夹子固定到环形空间。 然后将阀构件引入到环形空间中，并且接合构件被卡扣或以其它方式被引导成与紧固件接合以将阀构件相对于垫圈构件固定。

公开(公告)号：US20060235508A1

公开(公告)日：2006-10-19

申请号：US11279246

申请日：2006-04-10

申请人： Ernest Lane ,  Shouyan Lee ,  Charles Huang

发明人： Ernest Lane ,  Shouyan Lee ,  Charles Huang

IPC分类号： A61F2/24

CPC分类号： A61F2/2412 ,  A61F2/2409

摘要： A prosthetic heart valve assembly includes a gasket member and a valve member including a plurality of fasteners and a plurality of engagement members corresponding to the fasteners. The fasteners and/or engagement members may be configured to guide the engagement members into engagement with the fasteners. For example, the fasteners may include U-shaped spring-biased clips, e.g., attached to a core or other portion of a sewing cuff of the gasket member, and the engagement members may include latches or barbed protrusions that engage one or more holes in the fasteners. During use, the gasket member is introduced into a tissue annulus, and secured to the annulus, e.g., using a plurality of clips directed through the sewing cuff. The valve member is then introduced into the annulus and the engagement members are snapped or otherwise guided into engagement with the fasteners to secure the valve member relative to the gasket member.

摘要翻译： 假体心脏瓣膜组件包括垫圈构件和包括多个紧固件和对应于紧固件的多个接合构件的阀构件。 紧固件和/或接合构件可构造成引导接合构件与紧固件接合。 例如，紧固件可以包括U形弹簧偏置的夹子，例如，附接到垫圈构件的缝合箍的芯部或其他部分，并且接合构件可包括接合一个或多个孔的闩锁或有倒钩的突起 紧固件。 在使用期间，垫圈构件被引入到组织环中，并且例如通过使用穿过缝合袖带的多个夹子固定到环形空间。 然后将阀构件引入到环形空间中，并且接合构件被卡扣或以其它方式被引导成与紧固件接合以将阀构件相对于垫圈构件固定。

公开(公告)号：US07951197B2

公开(公告)日：2011-05-31

申请号：US12419059

申请日：2009-04-06

申请人： Ernest Lane ,  Shouyan Lee ,  Charles Huang

发明人： Ernest Lane ,  Shouyan Lee ,  Charles Huang

IPC分类号： A61F2/24

CPC分类号： A61F2/2412 ,  A61F2/2409

摘要： A prosthetic heart valve assembly includes a gasket member and a valve member including a plurality of fasteners and a plurality of engagement members corresponding to the fasteners. The fasteners and/or engagement members may be configured to guide the engagement members into engagement with the fasteners. For example, the fasteners may include U-shaped spring-biased clips, e.g., attached to a core or other portion of a sewing cuff of the gasket member, and the engagement members may include latches or barbed protrusions that engage one or more holes in the fasteners. During use, the gasket member is introduced into a tissue annulus, and secured to the annulus, e.g., using a plurality of clips directed through the sewing cuff. The valve member is then introduced into the annulus and the engagement members are snapped or otherwise guided into engagement with the fasteners to secure the valve member relative to the gasket member.

摘要翻译： 假体心脏瓣膜组件包括垫圈构件和包括多个紧固件和对应于紧固件的多个接合构件的阀构件。 紧固件和/或接合构件可构造成引导接合构件与紧固件接合。 例如，紧固件可以包括U形弹簧偏置的夹子，例如，附接到垫圈构件的缝合箍的芯部或其他部分，并且接合构件可包括接合一个或多个孔的闩锁或有倒钩的突起 紧固件。 在使用期间，垫圈构件被引入到组织环中，并且例如通过使用穿过缝合袖带的多个夹子固定到环形空间。 然后将阀构件引入到环形空间中，并且接合构件被卡扣或以其它方式被引导成与紧固件接合以将阀构件相对于垫圈构件固定。

公开(公告)号：US07513909B2

公开(公告)日：2009-04-07

申请号：US11279246

申请日：2006-04-10

申请人： Ernest Lane ,  Shouyan Lee ,  Charles Huang

发明人： Ernest Lane ,  Shouyan Lee ,  Charles Huang

IPC分类号： A61F2/24

CPC分类号： A61F2/2412 ,  A61F2/2409

摘要： A prosthetic heart valve assembly includes a gasket member and a valve member including a plurality of fasteners and a plurality of engagement members corresponding to the fasteners. The fasteners and/or engagement members may be configured to guide the engagement members into engagement with the fasteners. For example, the fasteners may include U-shaped spring-biased clips, e.g., attached to a core or other portion of a sewing cuff of the gasket member, and the engagement members may include latches or barbed protrusions that engage one or more holes in the fasteners. During use, the gasket member is introduced into a tissue annulus, and secured to the annulus, e.g., using a plurality of clips directed through the sewing cuff. The valve member is then introduced into the annulus and the engagement members are snapped or otherwise guided into engagement with the fasteners to secure the valve member relative to the gasket member.

摘要翻译： 假体心脏瓣膜组件包括垫圈构件和包括多个紧固件和对应于紧固件的多个接合构件的阀构件。 紧固件和/或接合构件可构造成引导接合构件与紧固件接合。 例如，紧固件可以包括U形弹簧偏置的夹子，例如，附接到垫圈构件的缝合箍的芯部或其他部分，并且接合构件可包括接合一个或多个孔的闩锁或有倒钩的突起 紧固件。 在使用期间，垫圈构件被引入到组织环中，并且例如通过使用穿过缝合袖带的多个夹子固定到环形空间。 然后将阀构件引入到环形空间中，并且接合构件被卡扣或以其它方式被引导成与紧固件接合以将阀构件相对于垫圈构件固定。

公开(公告)号：US08500802B2

公开(公告)日：2013-08-06

申请号：US13043211

申请日：2011-03-08

申请人： Ernest Lane ,  Shouyan Lee ,  Charles Huang

发明人： Ernest Lane ,  Shouyan Lee ,  Charles Huang

IPC分类号： A61F2/24

CPC分类号： A61F2/2412 ,  A61F2/2409

摘要： A prosthetic heart valve assembly includes a gasket member and a valve member including a plurality of fasteners and a plurality of engagement members corresponding to the fasteners. The fasteners and/or engagement members may be configured to guide the engagement members into engagement with the fasteners. For example, the fasteners may include U-shaped spring-biased clips, e.g., attached to a core or other portion of a sewing cuff of the gasket member, and the engagement members may include latches or barbed protrusions that engage one or more holes in the fasteners. During use, the gasket member is introduced into a tissue annulus, and secured to the annulus, e.g., using a plurality of clips directed through the sewing cuff. The valve member is then introduced into the annulus and the engagement members are snapped or otherwise guided into engagement with the fasteners to secure the valve member relative to the gasket member.

公开(公告)号：US20110190877A1

公开(公告)日：2011-08-04

申请号：US13043211

申请日：2011-03-08

申请人： Ernest Lane ,  Shouyan Lee ,  Charles Huang

发明人： Ernest Lane ,  Shouyan Lee ,  Charles Huang

IPC分类号： A61F2/24

CPC分类号： A61F2/2412 ,  A61F2/2409

摘要： A prosthetic heart valve assembly includes a gasket member and a valve member including a plurality of fasteners and a plurality of engagement members corresponding to the fasteners. The fasteners and/or engagement members may be configured to guide the engagement members into engagement with the fasteners. For example, the fasteners may include U-shaped spring-biased clips, e.g., attached to a core or other portion of a sewing cuff of the gasket member, and the engagement members may include latches or barbed protrusions that engage one or more holes in the fasteners. During use, the gasket member is introduced into a tissue annulus, and secured to the annulus, e.g., using a plurality of clips directed through the sewing cuff. The valve member is then introduced into the annulus and the engagement members are snapped or otherwise guided into engagement with the fasteners to secure the valve member relative to the gasket member.

摘要翻译： 假体心脏瓣膜组件包括垫圈构件和包括多个紧固件和对应于紧固件的多个接合构件的阀构件。 紧固件和/或接合构件可构造成引导接合构件与紧固件接合。 例如，紧固件可以包括U形弹簧偏置的夹子，例如，附接到垫圈构件的缝合箍的芯部或其他部分，并且接合构件可包括接合一个或多个孔的闩锁或有倒钩的突起 紧固件。 在使用期间，垫圈构件被引入到组织环中，并且例如通过使用穿过缝合袖带的多个夹子固定到环形空间。 然后将阀构件引入到环形空间中，并且接合构件被卡扣或以其它方式被引导成与紧固件接合以将阀构件相对于垫圈构件固定。

公开(公告)号：US20060276888A1

公开(公告)日：2006-12-07

申请号：US11144254

申请日：2005-06-03

申请人： Shouyan Lee ,  Ernest Lane

发明人： Shouyan Lee ,  Ernest Lane

IPC分类号： A61F2/24

CPC分类号： A61F2/2412 ,  A61F2/2415 ,  A61F2220/0075 ,  Y10S623/901

摘要： A method for making a bioprosthetic heart valve includes providing a non-contact cutting apparatus and a layer of tissue. The non-contact cutting apparatus may include a laser cutting system or high pressure water jet system. A leaflet is cut from the layer of tissue using a predefined template, and a plurality of alignment holes in the leaflet are created in the leaflet, e.g., along a peripheral edge. A support structure is provided having a plurality of alignment holes corresponding to alignment holes in the leaflet. The leaflet is secured to the support structure by securing one or more sutures through corresponding alignment holes in the leaflet and the support structure to provide a leaflet subassembly. A bioprosthetic heart valve is made by securing a set of leaflet subassemblies to a frame.

摘要翻译： 用于制造生物假体心脏瓣膜的方法包括提供非接触切割装置和组织层。 非接触切割设备可以包括激光切割系统或高压水喷射系统。 使用预定义的模板从组织层切割小叶，并且在小叶中产生小叶中的多个对准孔，例如沿着周边边缘。 提供了一种支撑结构，其具有对应于传单中的对准孔的多个对准孔。 通过将一个或多个缝线固定通过小叶和支撑结构中的对应的对准孔来将小叶固定到支撑结构，以提供小叶子组件。 生物假体心脏瓣膜通过将一组小叶组件固定到框架上而制成。

公开(公告)号：US20070203576A1

公开(公告)日：2007-08-30

申请号：US11743957

申请日：2007-05-03

申请人： Shouyan Lee ,  Ernest Lane

发明人： Shouyan Lee ,  Ernest Lane

IPC分类号： A61F2/24

CPC分类号： A61F2/2412 ,  A61F2/2415 ,  A61F2220/0075 ,  Y10S623/901

摘要： A method for making a bioprosthetic heart valve includes providing a non-contact cutting apparatus and a layer of tissue. The non-contact cutting apparatus may include a laser cutting system or high pressure water jet system. A leaflet is cut from the layer of tissue using a predefined template, and a plurality of alignment holes in the leaflet are created in the leaflet, e.g., along a peripheral edge. A support structure is provided having a plurality of alignment holes corresponding to alignment holes in the leaflet. The leaflet is secured to the support structure by securing one or more sutures through corresponding alignment holes in the leaflet and the support structure to provide a leaflet subassembly. A bioprosthetic heart valve is made by securing a set of leaflet subassemblies to a frame.

摘要翻译： 用于制造生物假体心脏瓣膜的方法包括提供非接触切割装置和组织层。 非接触切割设备可以包括激光切割系统或高压水喷射系统。 使用预定义的模板从组织层切割小叶，并且在小叶中产生小叶中的多个对准孔，例如沿着周边边缘。 提供了一种支撑结构，其具有对应于传单中的对准孔的多个对准孔。 通过将一个或多个缝线固定通过小叶和支撑结构中的对应的对准孔来将小叶固定到支撑结构，以提供小叶子组件。 生物假体心脏瓣膜通过将一组小叶组件固定到框架上而制成。

公开(公告)号：US07238200B2

公开(公告)日：2007-07-03

申请号：US11144254

申请日：2005-06-03

申请人： Shouyan Lee ,  Ernest Lane

发明人： Shouyan Lee ,  Ernest Lane

IPC分类号： A61F2/24

CPC分类号： A61F2/2412 ,  A61F2/2415 ,  A61F2220/0075 ,  Y10S623/901

摘要： A method for making a bioprosthetic heart valve includes providing a non-contact cutting apparatus and a layer of tissue. The non-contact cutting apparatus may include a laser cutting system or high pressure water jet system. A leaflet is cut from the layer of tissue using a predefined template, and a plurality of alignment holes in the leaflet are created in the leaflet, e.g., along a peripheral edge. A support structure is provided having a plurality of alignment holes corresponding to alignment holes in the leaflet. The leaflet is secured to the support structure by securing one or more sutures through corresponding alignment holes in the leaflet and the support structure to provide a leaflet subassembly. A bioprosthetic heart valve is made by securing a set of leaflet subassemblies to a frame.

摘要翻译： 用于制造生物假体心脏瓣膜的方法包括提供非接触切割装置和组织层。 非接触切割设备可以包括激光切割系统或高压水喷射系统。 使用预定义的模板从组织层切割小叶，并且在小叶中产生小叶中的多个对准孔，例如沿着周边边缘。 提供了一种支撑结构，其具有对应于传单中的对准孔的多个对准孔。 通过将一个或多个缝线固定通过小叶和支撑结构中的对应的对准孔来将小叶固定到支撑结构，以提供小叶子组件。 生物假体心脏瓣膜通过将一组小叶组件固定到框架上而制成。

公开(公告)号：US11259928B2

公开(公告)日：2022-03-01

申请号：US16534958

申请日：2019-08-07

申请人： Shouyan Lee

发明人： Shouyan Lee

IPC分类号： A61F2/24 ,  G01M13/003

摘要： A multifunctional prosthetic heart valve tester having a circuit of fluid channels, wherein the circuit has a main loop of fluid channel capable of providing a first flow path for a testing fluid. There can be a first branch-off point on the main loop having a first branch channel branching off and fluidly connecting the main loop to a three-way connection. There is a second branch-off point on the main loop having a second branch channel branching off and fluidly connecting the main loop to the three-way connection. A third branch-off point is provided on the main loop having a third branch channel branching off and fluidly connecting the main loop to the three-way connection. There is linear motor and a steady-flow pump disposed on the circuit. Wherein selective shut off of certain channels and selective on/off of the linear motor/steady flow pump allows the device to test the prosthetic valve in the following modes: the steady forward flow mode, steady backward flow mode, pulsatile mode, and hybrid mode.