专利检索 ap:("Etablissement Français du Sang" OR "Centre national de la recherche scientifique" OR "UNIVERSITE PAUL SABATIER TOULOUSE III" OR "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)") AND inv:"Nicolas ESPAGNOLLE" 第 1 页

1.

发明申请
SPECIFIC TLR4 ANTAGONIST IN THE TREATMENT OF MULTIPLE MYELOMA 有权

公开(公告)号：US20220023325A1

公开(公告)日：2022-01-27

申请号：US16472754

申请日：2017-12-22

申请人： Etablissement Français du Sang , Centre national de la recherche scientifique , UNIVERSITE PAUL SABATIER TOULOUSE III , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)

发明人： Nicolas ESPAGNOLLE , Frédéric DESCHASEAUX , Luc SENSEBE , Philippe BOURIN

IPC分类号： A61K31/7008 , A61P35/00

摘要： The present invention relates to a TLR4 (toll-like receptor 4) specific antagonist for use in the treatment of multiple myeloma in a subject suffering from multiple myeloma, and also to an antitumor pharmaceutical combination comprising (i) a TLR4-specific antagonist and (ii) a chemotherapy agent for simultaneous, separate or sequential use in the treatment of multiple myeloma.