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Patent Agency Ranking
公开(公告)号：US20180221021A1
公开(公告)日：2018-08-09
申请号：US15427963
申请日：2017-02-08
Applicant: Ethicon, Inc.
Inventor： Howard Scalzo , Leo B. Kriksunov , Robert J. Tannhauser , Emil Richard Skula
IPC: A61B17/06 , A61L17/10 , A61L17/00 , A61K31/085 , A61K31/155 , A61K38/44 , A61L17/04
Abstract: An implantable medical device and method of making it, including a collection of filaments, including a plurality of first variety filaments made of a first polymeric material and at least one second variety filament, and optionally at least one third variety of filament, wherein the second variety filament is coated or impregnated with a first biomedically useful agent and, if present, the third variety of filament is coated or impregnated with a second biomedically useful agent different from the first biomedically useful agent.
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公开(公告)号：US11504268B2
公开(公告)日：2022-11-22
申请号：US16019814
申请日：2018-06-27
Applicant: Ethicon, Inc.
Inventor： Howard Scalzo , Xintian Ming , Leo B. Kriksunov
Abstract: A disposable dressing forms a compartment around and above a wound site and a volatile antimicrobial compound is allowed to sublimate/evaporate into the compartment. A heating element is included in the dressing, with heat stimulating wound healing and simultaneously accelerating sublimation/evaporation of the antimicrobial compound.
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公开(公告)号：US20220323636A1
公开(公告)日：2022-10-13
申请号：US17708570
申请日：2022-03-30
Applicant: Ethicon, Inc.
Inventor： Howard Scalzo , Leo Kriksunov , Robert J. Tannhauser
Abstract: The present invention is directed to suturing systems having a needle, an elongated flexible suture having a connecting end attached to a said needle and an opposing free end and at least one elongated external beneficial filament that is attached to said needle or attached to said suture at the connecting end. The beneficial filament has a smaller cross-sectional area and lower mechanical strength than the suture and contains a medicant.
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公开(公告)号：US09149273B2
公开(公告)日：2015-10-06
申请号：US13802007
申请日：2013-03-13
Applicant: Ethicon, Inc.
Inventor： Howard Scalzo , Jerome A. Fischer , Stephen Rothenburger , Robert Cerwin , James R. McDivitt
CPC classification number: A61B17/06114 , A61B17/06166 , A61B50/00 , A61B2017/00889 , A61L17/005 , A61L2300/202 , A61L2300/404 , A61L2300/606
Abstract: A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.
Abstract translation: 一种制备包装的抗微生物缝合线的方法，包括以下步骤：提供基本上不含抗微生物剂的容纳隔室; 将缝合线定位在容纳隔室内，所述缝合线包括一个或多个表面，其上设置有抗微生物剂，所述抗微生物剂选自卤代羟基醚，酰氧基二苯醚及其组合; 将具有缝合线的容纳隔室放置在外包装中; 以及使外包装，容纳隔室和缝合线经受足以将有效量的抗微生物剂从缝线转移到容纳隔室的时间，温度和压力条件，同时将有效量的所述抗微生物剂保留在缝合线上， 从而基本上抑制缝合线和容纳隔室上的细菌定植。
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公开(公告)号：US20130193009A1
公开(公告)日：2013-08-01
申请号：US13802007
申请日：2013-03-13
Applicant: Ethicon, Inc.
Inventor： Howard Scalzo , Jerome A. Fischer , Stephen Rothenburger , Robert Cerwin , James R. McDivitt
IPC: A61B17/06
CPC classification number: A61B17/06114 , A61B17/06166 , A61B50/00 , A61B2017/00889 , A61L17/005 , A61L2300/202 , A61L2300/404 , A61L2300/606
Abstract: A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.
Abstract translation: 一种制备包装的抗微生物缝合线的方法，包括以下步骤：提供基本上不含抗微生物剂的容纳隔室; 将缝合线定位在容纳隔室内，所述缝合线包括一个或多个表面，其上设置有抗微生物剂，所述抗微生物剂选自卤代羟基醚，酰氧基二苯醚及其组合; 将具有缝合线的容纳隔室放置在外包装中; 以及使外包装，容纳隔室和缝合线经受足以将有效量的抗微生物剂从缝线转移到容纳隔室的时间，温度和压力条件，同时将有效量的所述抗微生物剂保留在缝合线上， 从而基本上抑制缝合线和容纳隔室上的细菌定植。
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